10.1093/rheumatology/keaa132
Quantifying and predicting the effect of anti-TNF therapy on axSpA-related fatigue: results from the BSRBR-AS registry and meta-analysis. [Dataset]
Shim, Joanna
Joanna
Shim
Dean, Linda E.
Linda E.
Dean
Karabayas, Maira
Maira
Karabayas
Jones, Gareth T.
Gareth T.
Jones
Macfarlane, Gary J.
Gary J.
Macfarlane
Basu, Neil
Neil
Basu
Oxford University Press
2020
atigue; Anti-tumour necrosis factor; Axial spondylarthritis; Sleep; Registry; Meta-analysis
2020-02-24
2017-12-31
Dataset
Effective management of axial spondyloarthritis (axSpA)-related fatigue is a major unmet clinical need. Anti-TNF therapy may reduce fatigue levels, although any effect has yet to be definitively quantified and predictors of any such improvements are unknown. Anti-TNF therapy results in a significant but modest reduction in fatigue amongst axSpA patients, with those reporting poor sleep quality most likely to report improvement. Effective management will likely require additional approaches. The accompanying file contains supplementary tables and figure.