Aggregation of Staphylococcus aureus following treatment with the antibacterial flavonol galangin.

Cushnie, T.P.T.; Hamilton, V.E.S.; Chapman, D.G.; Taylor, P.W.; Lamb, A. J.

doi:10.1111/j.1365-2672.2007.03393.x

Identification of bacterial isolates recovered from the surface of cleanroom operators' garments following wear. (2022)
Journal Article
SMITH, L.M., LOWES, C., O'DRISCOLL, N.H. and LAMB, A.J. 2022. Identification of bacterial isolates recovered from the surface of cleanroom operators' garments following wear. European journal of parenteral and pharmaceutical sciences [online], 27(3), article number 27301. Available from: https://doi.org/10.37521/ejpps.27301

Contamination of sterile pharmaceutical products can have serious consequences, in worst case scenario resulting in patient death. Cleanroom operators are the primary source of microbial contamination, where the surface of their specialist sterile cl... Read More about Identification of bacterial isolates recovered from the surface of cleanroom operators' garments following wear..

A comparison of the bacterial contamination of the surface of cleanroom operators’ garments following donning with and without gloves. (2021)
Journal Article
SMITH, L.M., O'DRISCOLL, N.H. and LAMB, A.J. 2021. A comparison of the bacterial contamination of the surface of cleanroom operators’ garments following donning with and without gloves. European journal of parenteral and pharmaceutical sciences [online], 26(3). Available from: https://doi.org/10.37521/ejpps.26302

Specialist cleanroom garments are a potential vector for transmission of microorganisms within these facilities. In order to maintain the low bioburden of such clothing it has been perceived best practice for operators to dress wearing sterile cleanr... Read More about A comparison of the bacterial contamination of the surface of cleanroom operators’ garments following donning with and without gloves..

Gender influences bacterial contamination of reusable cleanroom operators’ garments following wear. (2020)
Journal Article
SMITH, L.M., O'DRISCOLL, N.H. and LAMB, A.J. 2020. Gender influences bacterial contamination of reusable cleanroom operators’ garments following wear. European journal of parenteral and pharmaceutical sciences [online], 25(2), article 2. Available from: https://doi.org/10.37521/ejpps25202

Background: Operators are the primary source of cleanroom contamination, with the majority of their detritus identified as skin squames and their associated microorganisms. To reduce contamination, operatives are required to wear a specific arrangeme... Read More about Gender influences bacterial contamination of reusable cleanroom operators’ garments following wear..

Colistin causes profound morphological alteration but minimal cytoplasmic membrane perforation in populations of Escherichia coli and Pseudomonas aeruginosa. (2018)
Journal Article
O'DRISCOLL, N.H., CUSHNIE, T.P.T., MATTHEWS, K.H. and LAMB, A.J. 2018. Colistin causes profound morphological alteration but minimal cytoplasmic membrane perforation in populations of escherichia coli and pseudomonas aeruginosa. Archives of microbiology [online], 200(5), pages 793-802. Available from: https://doi.org/10.1007/s00203-018-1485-3

Whilst colistin (polymyxin E) represents the last mainstream treatment option for multi-drug resistant Gram-negative pathogens, details of its mechanism of action remain to be fully resolved. In this study, the effects of sub-inhibitory, inhibitory-b... Read More about Colistin causes profound morphological alteration but minimal cytoplasmic membrane perforation in populations of Escherichia coli and Pseudomonas aeruginosa..

Morphological and ultrastructural changes in bacterial cells as an indicator of antibacterial mechanism of action. (2016)
Journal Article
CUSHNIE, T.P.T., O'DRISCOLL, N.H. and LAMB, A.J. 2016. Morphological and ultrastructural changes in bacterial cells as an indicator of antibacterial mechanism of action. Cellular and molecular life sciences [online], 73(23), pages 4471-4492. Available from: https://doi.org/10.1007/s00018-016-2302-2

Efforts to reduce the global burden of bacterial disease and contend with escalating bacterial resistance are spurring innovation in antibacterial drug and biocide development and related technologies such as photodynamic therapy and photochemical di... Read More about Morphological and ultrastructural changes in bacterial cells as an indicator of antibacterial mechanism of action..

Evaluation of the practice of veterinary pharmacy. (2015)
Journal Article
O'DRISCOLL, N.H., LABOVITIADI, O. and LAMB, A.J. 2015. Evaluation of the practice of veterinary pharmacy. Currents in pharmacy teaching and learning [online], 7(5), pages 606-613. Available from: https://doi.org/10.1016/j.cptl.2015.06.017

Background: In the United Kingdom (UK), pharmacists' roles have expanded considerably in recent decades to encompass clinical practice through more direct patient care. However, dispensing and compounding remain core activities for pharmacists. A lac... Read More about Evaluation of the practice of veterinary pharmacy..

Alkaloids: an overview of their antibacterial, antibiotic-enhancing and antivirulence activities. (2014)
Journal Article
CUSHNIE, T.P.T., CUSHNIE, B. and LAMB, A.J. 2014. Alkaloids: an overview of their antibacterial, anibiotic-enhancing and antivirulence activities. International journal of antimicrobial agents [online], 44(5), pages 377-386. Available from: https://doi.org/10.1016/j.ijantimicag.2014.06.001

With reports of pandrug-resistant bacteria causing untreatable infections, the need for new antibacterial therapies is more pressing than ever. Alkaloids are a large and structurally diverse group of compounds that have served as scaffolds for import... Read More about Alkaloids: an overview of their antibacterial, antibiotic-enhancing and antivirulence activities..

Veterinary pharmacy within the United Kingdom: review of current practice and education. (2014)
Journal Article
O'DRISCOLL, N.H., JUWAH, C., LABOVITIADI, O. and LAMB, A.J. 2014. Veterinary pharmacy within the United Kingdom: review of current practice and education. Pharmacy education [online], 14, pages 26-30. Available from: https://pharmacyeducation.fip.org/pharmacyeducation/article/view/188

Background: Pharmacists have acknowledged roles as medicines experts facilitating human healthcare. Such expertise is also applicable in pharmaceutical treatments for non-human animals. Aims: The aims were to review the perceptions and extent to whic... Read More about Veterinary pharmacy within the United Kingdom: review of current practice and education..

Aggregation of Staphylococcus aureus following treatment with the antibacterial flavonol galangin. (2007)
Journal Article
CUSHNIE, T.P.T., HAMILTON, V.E.S., CHAPMAN, D.G., TAYLOR, P.W. and LAMB, A.J. 2007. Aggregation of Staphylococcus aureus following treatment with the antibacterial flavonol galangin. Journal of applied microbiology [online], 103(5), pages 1562-1567. Available from: https://doi.org/10.1111/j.1365-2672.2007.03393.x

Aim: The flavonol galangin, an antimicrobial constituent of the traditional medicines propolis and Helichrysum aureonitens, is being assessed as part of an ongoing investigation into the antibacterial activity of flavonoids. The present study sought... Read More about Aggregation of Staphylococcus aureus following treatment with the antibacterial flavonol galangin..

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