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Weight loss and cholesterol lowering in the elderly. (2010)
Journal Article
ROLLAND, C. and BROOM, I. 2010. Weight loss and cholesterol lowering in the elderly. GM2: peer-reviewed medicine for the 50+ patient [online], 40(1), pages 27-36. Available from: https://www.gmjournal.co.uk/weight-loss-and-cholesterol-lowering-in-the-elderly

Weight loss and cholesterol lowering in the elderly remains a controversial issue. Obesity is considered to be problematic as a result of associated dyslipidemia, cardiovascular disease and mortality. Diet, exercise, medication and laparoscopic gastr... Read More about Weight loss and cholesterol lowering in the elderly..

Engaging patients, clinicians and health funders in weight management: the Counterweight Programme. (2008)
Journal Article
MCQUIGG, M., BROWN, J.E., BROOM, J.I., LAWS, R.A., RECKLESS, J.P.D., NOBLE, P.A., KUMAR, S., MCCOMBIE, E.L., LEAN, M.E.J., LYONS, G.F., MONGIA, S., FROST, G.S., QUINN, M.F., BARTH, J.H., HAYNES, S.M., FINER, N., HASLAM, D.W., ROSS, H.M., HOLE, D.J. and RADZIWONIK, S. 2008. Engaging patients, clinicians and health funders in weight management: the Counterweight Programme. Family practice [online], 25(Supplement 1), pages i79-i86. Available from: https://doi.org/10.1093/fampra/cmn081

Background. The Counterweight Programme provides an evidence based and effective approach for weight management in routine primary care. Uptake of the programme has been variable for practices and patients. Aim. To explore key barriers and facilitato... Read More about Engaging patients, clinicians and health funders in weight management: the Counterweight Programme..

Thinking around abdominal obesity and cardiovascular risk. (2006)
Journal Article
BROOM, I. 2006. Thinking around abdominal obesity and cardiovascular risk. British journal of diabetes and vascular disease, 6(2), pages 58-61.

Obesity, particularly abdominal (visceral) obesity, is a burden on healthcare systems worldwide and is a leading cause of cardiovascular disease (CVD), insulin resistance, Type 2 diabetes, dyslipidaemia, metabolic syndrome, inflammation and thrombosi... Read More about Thinking around abdominal obesity and cardiovascular risk..

Selenoprotein gene expression in an intestinal cell line during selenium depletion: a macroarray approach indicates effects on SelW and glutathione peroxidise 1. (2003)
Journal Article
PAGMANTIDIS, V., VILLETTE, S., BERMANO, G., BROOM, J., ARTHUR, J.R. and HESKETH, J.E. 2003. Selenoprotein gene expression in an intestinal cell line during selenium depletion: a macroarray approach indicates effects on SelW and glutathione peroxidise 1. Proceedings of the Nutrition Society [online], 62(1A), page 72A. Available from: https://doi.org/10.1017/S0029665103000776

The micronutrient selenium (Se) is incoprprated into a renage of selenoproteins involved in numerous biochemical processes within the body.

Systematic review of exercise and the long-term outcomes of the treatment for obesity. (2002)
Journal Article
BROWN, T.J., AVENELL, A., BROOM, J., SMITH, W.C.S., JUNG, R., CAMPBELL, M.K. and GRANT, A.M. 2002. Systematic review of exercise and the long-term outcomes of the treatment for obesity. Proceedings of the Nutrition Society [online], 61(3A), page 154A. Available from: https://doi.org/10.1017/S0029665102000289

We systematically reviewed randomised controlled trials (RCTs) of obesity treatments in adults and assessed long term effects on weight and risk factors for disease.

Stimulation of colorectal tumour protein synthesis, in vivo, by nutritional support. (1990)
Journal Article
HEYS, S.D., PARK, K.G.M., McNURLAN, M.A., MILNE, E., KEENAN, R.A., MILLER, J.D.B., BROOM, J., EREMIN, O. and GARLICK, P.J. 1990. Stimulation of colorectal tumour protein synthesis, in vivo, by nutritional support. Proceedings of the Nutrition Society [online], 49(2), page 165A. Available from: https://doi.org/10.1079/PNS19900038

Malignant disease is frequently accompanied by weight loss and malnutrition, which are associated with an increase in patient mortality and morbidity.

A study of the time course of fructose-2, 6-bisphosphate production in a septic mouse model. (1986)
Journal Article
HEPBURN, D., BROOM, J. and SMITH, D.J. 1986. A study of the time course of fructose-2, 6-bisphosphate production in a septic mouse model. Proceedings of the Nutrition Society [online], 45(1), page 33A. Available from: https://doi.org/10.1079/PNS19860044

Where sepsis occurs in the post-surgical period, mortality rates tend to be high. In sepsis, metabolism is grossly disrupted with glucose becoming the preferred fuel for energy provision even where ketogenesis has been promoted.

The effects of postoperative metabolic support on lipolytic rates in patients undergoing elective abdominal surgery. (1986)
Journal Article
BROOM, J., BRACKENRIDGE, I.E., SIMPSON, E., MILLER, J.D.B. and MORRISON, I. 1986. The effects of postoperative metabolic support on lipolytic rates in patients undergoing elective abdominal surgery. Proceedings of the Nutrition Society [online], 45(1), page 20A. Available from: https://doi.org/10.1079/PNS19860042

The metabolic response to trauma is associated with mobilization of energy substrates including fat or fat-derived substrates.

Changes in body composition after thermal injury in the rat. (1979)
Journal Article
AL SHAMMA, G.A., GOLL. C.C., BAIRD, T.B., BROOM, J., NICHOLAS, G.A. and RICHARDS, J.R. 1979. Changes in body composition after thermal injury in the rat. British journal of nutrition [online], 42(3), pages 367-375. Available at: https://doi.org/10.1079/BJN19790126

1. The effects on body composition, measured by direct techniques, of a controlled 25% body-surfacearea thermal injury have been studied in two groups of forty male Wistar rats. 2. The extent of weight loss in the animals was directly related to thei... Read More about Changes in body composition after thermal injury in the rat..

Biochemical adaptations in early starvation: observations on sex difference. (1978)
Journal Article
BROOM, J., FLECK, A., DAVIDSON, D.F., ROSENBURG, C. and DURNIN, J.V.G.A. 1978. Biochemical adaptations in early starvation: observations on sex difference. Proceedings of the Nutrition Society [online], 37(3), page 92A. Available from: https://doi.org/10.1079/PNS19780048

Twenty-two students, eleven male and eleven female, volunteered to fast for 3 d. Twenty-four hour urine collections were obtained over the period of study, and total nitrogen, urea, and 3-hydroxybutyrate (3-OH-butyrate) were determined in each.

Protein synthesis in the rat liver after fracture of the femur. (1974)
Journal Article
KHAN, S.N., TILSTONE, W.J., FLECK, A. and BROOM, I. 1974. Protein synthesis in the rat liver after fracture of the femur. Proceedings of the Nutrition Society [online], 33(3), pages 93A-94A. Available from: https://doi.org/10.1079/PNS19740058

Moderate to severe trauma is accompanied by two characteristic responses in plasma protein concentration, namely an increase in levels of acute phase reactants and a fall in albumin (Cuthbertson & Tompsett, 1935; Oweb, 1967).