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All Outputs (37)

Support for current and aspiring women leaders: an exploration of UK higher education institutions' responses. (2019)
Report
DIACK, L., PEDERSEN, S., MACLENNAN, S., FALCONER, M., GILLIBRAND, E., MCFADYEN, M. and WATSON, A. 2019. Support for current and aspiring women leaders: an exploration of UK higher education institutions' responses. London: Advance-HE [online]. Available from: https://www.lfhe.ac.uk/filemanager/root/site_assets/research_resources/small_development_projects/sdp_19/support/046_AdvHE_Support_aspiring_women_final.pdf

This research was funded by Advance HE’s Small Development Fund to explore higher education institutions' (HEIs') mechanisms for the support and advancement of current and aspiring women leaders. Over recent years there has been an increase in the nu... Read More about Support for current and aspiring women leaders: an exploration of UK higher education institutions' responses..

A Scottish and Japanese experience of patient-centred diabetic care: descriptive study of interprofessional education on live webinar. (2018)
Journal Article
SUEMATSU, M., JOSEPH, S., ABE, K., YASUI, H., TAKAHASHI, N., OKAZAKI, K., HAXTON, J., MCFADYEN, M., WALKER, P. and DIACK, L. 2018. A Scottish and Japanese experience of patient-centred diabetic care: descriptive study of interprofessional education on live webinar. Nagoya journal of medical science [online], 80(4), pages 465-473. Available from: https://doi.org/10.18999/nagjms.80.4.465

To minimise the global burden of diabetes, the awareness of appropriate intervention methods for diabetes education and practice is essential. This project is the first international interprofessional education (IIPE) for the awareness of diabetes, w... Read More about A Scottish and Japanese experience of patient-centred diabetic care: descriptive study of interprofessional education on live webinar..

I can step outside my comfort zone. (2017)
Journal Article
MCFADYEN, M.C.E. and DIACK, L. 2017. I can step outside my comfort zone. Pharmacy [online], 5(4), article number 59. Available from: https://doi.org/10.3390/pharmacy5040059

On embarking upon such a multifactorial, professional degree as Pharmacy, students often find it difficult to meld the scientific- and practice-based components of the course. In final year of the undergraduate Masters of Pharmacy degree (MPharm) wit... Read More about I can step outside my comfort zone..

Access to forensic science. [Case study] (2015)
Report
GOUA, M., COWIE, E., DEEGAN, W., MACMANUS, S., MCFADYEN, M. and MCKENZIE, C. 2015. Access to forensic science. [Case study]. Snapshots@RGU, July 2015. Aberdeen: Robert Gordon University.

This case study discusses an after-school programme for secondary-school pupils from "low attainment/progression" schools, which aimed to facilitate wider access to university - particularly in STEM subjects. The course focused specifically on toxico... Read More about Access to forensic science. [Case study].

Now it's over to you: a workbook approach. (2015)
Book Chapter
MCFADYEN, M.C.E. 2015. Now it's over to you: a workbook approach. In Thomas, L. (ed.) Compendium of effective practice in directed independent learning. York: Higher Education Academy [online], pages 85-87. Available from: https://www.advance-he.ac.uk/knowledge-hub/compendium-effective-practice-directed-independent-learning

During the oncology topic within the third year 'Clinical Pharmacology and Therapeutics 2' module (CPT2) of the MPharm at Robert Gordon University (RGU), it quickly became apparent that students had difficulty in placing complex concepts into context... Read More about Now it's over to you: a workbook approach..

Playing games in IPE: a Japanese and Scottish experience. (2014)
Report
DIACK, L., JOSEPH, S., HAXTON, J.I. and MCFADYEN, M.C.E. 2014. Playing games in IPE: a Japanese and Scottish experience. Aberdeen: Robert Gordon University.

This report describes the outcomes of a project funded by the Great Britain Sasakawa Foundation in 2013, which aimed to develop an educational toolkit for health and social care students and professionals.

Exploring just-in-time teaching 3D development as a tool for enhancing knowledge and understanding. (2013)
Journal Article
MCFADYEN, M.C.E. and WATSON, E.W. 2013. Exploring just-in-time teaching 3D development as a tool for enhancing knowledge and understanding. Pharmacy [online], 1(2), 269-281. Available from: https://doi.org/10.3390/pharmacy1020269

The integumentary system (skin) is the first line of defence in the body and part of the innate immune system. Within first-year modules on Pharmaceutical Biology and Integrative Physiology in the Masters of Pharmacy degree at Robert Gordon Universit... Read More about Exploring just-in-time teaching 3D development as a tool for enhancing knowledge and understanding..

Development and evaluation of a novel interprofessional learning activity addressing the management of phenylketonuria. (2013)
Journal Article
DONALD, H., MCFADYEN, M.C.E. and BOYLE, S.P. 2013. Development and evaluation of a novel interprofessional learning activity addressing the management of phenylketonuria. Creative education [online], 4(3), pages 189-193. Available from: https://doi.org/10.4236/ce.2013.43028

This new initiative across the School of Pharmacy and Life Sciences at Robert Gordon University focuses around students from the Overseas Pharmacist's Assessment Programme (OSPAP), and third-year Nutrition and Dietetics students working in an interpr... Read More about Development and evaluation of a novel interprofessional learning activity addressing the management of phenylketonuria..

Integrative physiology: the integumentary system. [Case study] (2013)
Report
MCFADYEN, M.C.E. and WATSON, E. 2013. Integrative physiology: the integumentary system. [Case study]. Snapshots@RGU, February 2013. Aberdeen: Robert Gordon University.

This case study discusses the development of a three-dimensional e-Learning software package, designed to help teach students on a first-year "Integrative Physiology" module about the skin and integumentary system.

Cytochrome P450 mRNA profile in human breast cancer cell lines. (2008)
Thesis
WARASIHA, B. 2008. Cytochrome P450 mRNA profile in human breast cancer cell lines. Robert Gordon University, PhD thesis.

Cytochrome P450 enzymes (P450s) are involved in cancer development and treatment due to their roles in the oxidative metabolism of various compounds, both endogenous (e.g. oestrogen) and exogenous (e.g. tamoxifen). Intermediate P450 metabolites deriv... Read More about Cytochrome P450 mRNA profile in human breast cancer cell lines..

Cytochrome P450 CYP1B1 activity in renal cell carcinoma. (2004)
Journal Article
MCFADYEN, M.C.E., MELVIN, W.T. and MURRAY, G.I. 2004. Cytochrome P450 CYP1B1 activity in renal cell carcinoma. British journal of cancer [online], 91, pages 966-971. Available from: https://doi.org/10.1038/sj.bjc.6602053

Renal cell carcinoma (RCC) is the most common malignancy of the kidney and has a poor prognosis due to its late presentation and resistance to current anticancer drugs. One mechanism of drug resistance, which is potentially amenable to therapeutic in... Read More about Cytochrome P450 CYP1B1 activity in renal cell carcinoma..

Use of CYP1B1 inhibitors for treating cancer. (2001)
Patent
MURRAY, G.I., MELVIN, W.T. and MCFADYEN, M. 2001. Use of CYP1B1 inhibitors for treating cancer. International patent application PCT/GB2001/000548. International publication number WO/2001/058444 (WO 01/58444 A1), published 16.08.2001. Available from: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2001058444

CYP1B1 proteins and their role in metabolising or inactivating anti-cancer drugs are disclosed, together with compositions for treating cancer comprising a substance capable of inhibiting CYP1B1 protein and an anti-cancer drug (e.g. docetaxel, paclit... Read More about Use of CYP1B1 inhibitors for treating cancer..

Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer. (2001)
Journal Article
MCFADYEN, M.C.E., CRUICKSHANK, M.E., MILLER, I.D., MCLEOD, H.L., MELVIN, W.T., HAITES, N.E., PARKIN, D. and MURRAY, G.I. 2001. Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer. British journal of cancer [online], 85(2), pages 242-246. Available from: https://doi.org/10.1054/bjoc.2001.1907

Ovarian cancer is the most frequent cause of death from gynaecological malignancies world wide. Little improvement has been made in the long-term outcome of this disease, with the 5-year survival of patients only 30%. This poor prognosis is due to th... Read More about Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer..

Cytochrome P450 CYP3A in human renal cell cancer. (1999)
Journal Article
MURRAY, G.I., MCFADYEN, M.C.E., MITCHELL, R.T., CHEUNG, Y.-L., KERR, A.C. and MELVIN, W.T. 1999. Cytochrome P450 CYP3A in human renal cell cancer. British journal of cancer [online], 79(11-12), pages 1836-1842. Available from: https://doi.org/10.1038/sj.bjc.6690292

Renal cell cancer is the main malignant tumour of the kidney and has an increasing incidence. This type of tumour has a poor prognosis and shows intrinsic resistance to several anti-cancer drugs. The CYP3A P450 family, which consists of three closely... Read More about Cytochrome P450 CYP3A in human renal cell cancer..

Polyamide profiles of porcine milk and of intestinal tissue of pigs during suckling. (1991)
Journal Article
KELLY, D., KING, T.P., BROWN, D.S. and MCFADYEN, M. 1991. Polyamide profiles of porcine milk and of intestinal tissue of pigs during suckling. Reproduction nutrition development [online], 31(1), pages 73-80. Available from: https://doi.org/10.1051/rnd:19910107

Previous studies have suggested that luminal polyamines can directly influence intestinal differentiation of neonatal rats. The present investigation has demonstrated the presence of high levels of polyamines in porcine milk and in the intestinal tis... Read More about Polyamide profiles of porcine milk and of intestinal tissue of pigs during suckling..

Pattern of gastric emptying in the pig: relation to feeding. (1990)
Journal Article
GREGORY, P.C., MCFADYEN, M. and RAYNER, D.V. 1990. Pattern of gastric emptying in the pig: relation to feeding. British journal of nutrition [online], 64(1), pages 45-58. Available from: https://doi.org/10.1079/bjn19900008

The aims of the present study were to compare the gastric emptying of dry matter (DM) and liquids during the feeding period with that following meal consumption, to clarify the relationship between feeding and gastric emptying, and to investigate how... Read More about Pattern of gastric emptying in the pig: relation to feeding..

Cytochrome P450 CYP1B1 in breast cancer.
Presentation / Conference Contribution
MURRAY, G.I., BUCHAN, S., MCFADYEN, M.C.E., MILLER, I.D., PAYNE, S. and MELVIN, W.T. 1998. Cytochrome P450 CYP1B1 in breast cancer. Presented at the 1998 Joint special conference of the British Association for Cancer Research and the Royal Society of Medicine (Oncology Section), 7-8 December 1998, London, UK.

This poster gives an overview of recent research into cytochrome P450 CYP1B1, which has previously been shown to present increased expression in several types of human cancer. This study specifically used immunohistochemistry to investigate the expre... Read More about Cytochrome P450 CYP1B1 in breast cancer..

Cytochrome P450 in human brain tumours.
Presentation / Conference Contribution
MCFADYEN, M.C.E., MELVIN, W.T. and MURRAY, G.I. 1997. Cytochrome P450 in human brain tumours. Presented at the 1997 Joint winter meeting of the British Association for Cancer Research, the Association of Cancer Physicians and the Royal Society of Medicine (Oncology Section), 27-28 November 1997, London, UK.

This presentation reports on a study investigating the presence and cellular localization of individual families of cytochrome P450 enzymes, in both normal brain and primary brain tumours. The immunoreactivity of individual P450s was identified using... Read More about Cytochrome P450 in human brain tumours..

Cytochrome P450 in normal human brain and brain tumours.
Presentation / Conference Contribution
MCFADYEN, M.C.E., MELVIN, W.T. and MURRAY, G.I. 1997. Cytochrome P450 in normal human brain and brain tumours. Presented at the July 1997 Biochemical Society meeting, 29-31 July 1997, Dundee, UK.

Cytochromes P450 are a multi-gene family of constitutive and inducible haem-containing enzymes, with a critical role in the oxidative metabolism of a wide range of environmental chemicals - including carcinogens, toxins and therapeutic drugs. P450s m... Read More about Cytochrome P450 in normal human brain and brain tumours..