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All Outputs (2)

Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer. (2001)
Presentation / Conference
MCFADYEN, M.C.E., CRUICKSHANK, M.E., MILLER, I.D., MELVIN, W.T. and MURRAY, G.I. 2001. Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer. Presented at the 183rd Meeting of the Pathological Society of Great Britain and Ireland, 3-6 July 2001, Liverpool, UK.

Ovarian cancer is the leading cause of death from gynaecological malignances worldwide. This paper discusses a study in which the presence of CYP1B1 in primary and metastatic ovarian cancer was investigated through immunohistochemistry. The aim of th... Read More about Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer..

Cytochrome P450 CYP1B1: a novel mechanism of drug resistance. (2001)
Presentation / Conference
MCFADYEN, M.C.E., MELVIN, W.T. and MURRAY, G.I. 2001. Cytochrome P450 CYP1B1: a novel mechanism of drug resistance. Presented at the 2001 British cancer research meeting (BCRM 2001), 1-4 July 2001, Leeds, UK.

CYP1B1 is a member of the cytochrome P450 enzymes, which are central to the oxidative metabolism of a wide range of substrates, including endogenous compounds involved in cell signaling, environmental carcinogens and anti-cancer drugs. This presentat... Read More about Cytochrome P450 CYP1B1: a novel mechanism of drug resistance..