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All Outputs (4)

Genome-guided bioprospecting for novel antibiotic lead compounds. (2023)
Thesis
AWOLOPE, O.K. 2023. Genome-guided bioprospecting for novel antibiotic lead compounds. Robert Gordon University, PhD thesis. Hosted on OpenAIR [online]. Available from: https://doi.org/10.48526/rgu-wt-1987833

Antimicrobial resistance continues to pose a threat to health and wellbeing. Unmitigated, it is predicted to be the leading cause of death by 2050. Hence, the sustained development of novel antibiotics is crucial. As over 60% of licensed antibiotics... Read More about Genome-guided bioprospecting for novel antibiotic lead compounds..

De novo genome assembly and analysis unveil biosynthetic and metabolic potentials of Pseudomonas fragi A13BB. [Dataset] (2021)
Dataset
AWOLOPE, O.K., O'DRISCOLL, N.H., DI SALVO, A. and LAMB, A.J. 2021. De novo genome assembly and analysis unveil biosynthetic and metabolic potentials of Pseudomonas fragi A13BB. [Dataset]. BMC genomic data [online], 22, article number 15. Available from: https://doi.org/10.1186/s12863-021-00969-0

Objectives; The role of rhizosphere microbiome in supporting plant growth under biotic stress is well documented. Rhizobacteria ward off phytopathogens through various mechanisms including antibiosis. We sought to recover novel antibiotic-producing b... Read More about De novo genome assembly and analysis unveil biosynthetic and metabolic potentials of Pseudomonas fragi A13BB. [Dataset].

The complete genome sequence of Hafnia alvei A23BA: a potential antibiotic-producing rhizobacterium. [Dataset] (2021)
Dataset
AWOLOPE, O.K., O'DRISCOLL, N.H., DI SALVO, A. and LAMB, A.J. 2021. The complete genome sequence of Hafnia alvei A23BA: a potential antibiotic-producing rhizobacterium. [Dataset]. BMC research notes [online], 14, article number 8. Available from: https://doi.org/10.1186/s13104-020-05418-2

Objectives: The urgent need for novel antibiotics cannot be overemphasized. Hafnia alvei A23BA was isolated from plant rhizosphere as part of an effort to recover novel antibiotic-producing bacterial strains from soil samples. The genome of the isola... Read More about The complete genome sequence of Hafnia alvei A23BA: a potential antibiotic-producing rhizobacterium. [Dataset].

Genome-guided screening of bacterial isolates to identify potential antibiotic producers. (2019)
Presentation / Conference
AWOLOPE, O.K., O'DRISCOLL, N.H. and LAMB, A. 2019. Genome-guided screening of bacterial isolates to identify potential antibiotic producers. Presented at the 2019 Microbiology Society annual conference, 8-11 April 2019, Belfast, UK.

The urgent need for new antibiotics cannot be overemphasized. Bacterial secondary metabolites remain a relatively untapped source of new therapies. The ability to produce these bioactive compounds is however not universal to all bacterial species. Tw... Read More about Genome-guided screening of bacterial isolates to identify potential antibiotic producers..