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All Outputs (3)

An investigation into the molecular mechanisms of hyperbaric oxygen using a human dermal microvascular endothelial cell line and a porcine retinal explant model. (2019)
Thesis
IWUAGWU, B.U. 2019. An investigation into the molecular mechanisms of hyperbaric oxygen using a human dermal microvascular endothelial cell line and a porcine retinal explant model. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

Diabetes is a debilitating metabolic condition with associated vascular complications that are a major cause of morbidity and mortality. Endothelial dysfunction is central to microvascular complications such as diabetic retinopathy (DR) and impaired... Read More about An investigation into the molecular mechanisms of hyperbaric oxygen using a human dermal microvascular endothelial cell line and a porcine retinal explant model..

The effect of single nucleotide polymorphisms and metabolic substrates on the cellular distribution of mammalian BK channels. (2017)
Thesis
ADEYILEKA-TRACZ, B.A. 2017. The effect of single nucleotide polymorphisms and metabolic substrates on the cellular distribution of mammalian BK channels. Robert Gordon University, PhD thesis.

Humans are approximately 99% similar with inter-individual differences caused in part by single-nucleotide polymorphisms (SNPs), which poses a challenge for the effective treatment of disease. Bioinformatics resources can help to store and analyse ge... Read More about The effect of single nucleotide polymorphisms and metabolic substrates on the cellular distribution of mammalian BK channels..

Hypoxia-induced responses of porcine pulmonary veins. (2017)
Thesis
ARNOLD, A. 2017. Hypoxia-induced responses of porcine pulmonary veins. Robert Gordon University, PhD thesis.

The pulmonary vein (PV) constricts to hypoxia however little is known about the underlying mechanisms. Hypoxic PV constriction is proposed to recruit upstream capillary beds and optimise gas exchange in healthy humans and may play a role in high alti... Read More about Hypoxia-induced responses of porcine pulmonary veins..