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All Outputs (5)

Exploring the role of Wnt signalling in heart failure with preserved ejection fraction. (2022)
Thesis
PAUL, M.A. 2022. Exploring the role of Wnt signalling in heart failure with preserved ejection fraction. Robert Gordon University, PhD thesis. Hosted on OpenAIR [online]. Available from: https://doi.org/10.48526/rgu-wt-1987960

According to the European Society of Cardiology long-term out-patient registry, heart failure with preserved ejection fraction (HFpEF) accounts for approximately 16% of heart failure cases, with survival rates failing to improve due to the lack of ef... Read More about Exploring the role of Wnt signalling in heart failure with preserved ejection fraction..

Studies on the role of zinc in maintaining antioxidant status in the heart. (2020)
Thesis
OKAFOR, O.A.G. 2020. Studies on the role of zinc in maintaining antioxidant status in the heart. Robert Gordon University, MRes thesis. Hosted on OpenAIR [online]. Available from: https://openair.rgu.ac.uk

Zinc (Zn2+) is an essential micronutrient which plays a pivotal role as a signalling, catalytic and structural component in cells and functions in several physiological processes such as immune function, wound healing, cognition, reproduction and as... Read More about Studies on the role of zinc in maintaining antioxidant status in the heart..

Determining the role of the LPI/GPR55 system in the development of obesity and associated cardiovascular consequences. (2018)
Thesis
HAIR, S.C. 2018. Determining the role of the LPI/GPR55 system in the development of obesity and associated cardiovascular consequences. Robert Gordon University, PhD thesis.

Obesity has reached worldwide epidemic proportions and with this increased incidence of obesity, comes an increase in incidence of the comorbidities associated with obesity such as diabetes and cardiovascular disease (CVD). The underlying mechanisms... Read More about Determining the role of the LPI/GPR55 system in the development of obesity and associated cardiovascular consequences..

Studies on the role of GPR55 in cardiovascular physiology and pathophysiology. (2017)
Thesis
ROBERTSON-GRAY, O.J. 2017. Studies on the role of GPR55 in cardiovascular physiology and pathophysiology. Robert Gordon University, PhD thesis.

Atherosclerosis is a multifactorial, chronic inflammatory condition characterised by endothelial dysfunction, hyperlipidaemia and the accumulation of fatty deposits within the tunica intima of medium-to-large sized muscular arteries. This disease can... Read More about Studies on the role of GPR55 in cardiovascular physiology and pathophysiology..

Studies investigating the mechanisms of the cardioprotective effects of Cannabidiol. (2014)
Thesis
HEPBURN, C.Y. 2014. Studies investigating the mechanisms of the cardioprotective effects of Cannabidiol. Robert Gordon University, PhD thesis.

The phytocannabinoid cannabidiol (CBD) has a complex pharmacology which is thought to include, but is not limited to, an ability to act as an inverse agonist at the CB1 and CB2 receptors and an antagonist of GPR55. Moreover, is has been shown to redu... Read More about Studies investigating the mechanisms of the cardioprotective effects of Cannabidiol..