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Meta-analysis demonstrates Gly482Ser variant of PPARGC1A is associated with components of metabolic syndrome within Asian populations. (2019)
Journal Article
BHATTA, P., BERMANO, G., WILLIAMS, H.C. and KNOTT, R.M. 2020. Meta-analysis demonstrates Gly482Ser variant of PPARGC1A is associated with components of metabolic syndrome within Asian populations. Genomics [online], 112(2), pages 1795-1803. Available from: https://doi.org/10.1016/j.ygeno.2019.10.011

To determine the association of peroxisome proliferator activated receptor gamma coactivator 1 Gly482Ser variant with components of metabolic syndrome. Materials and methods:- A systematic search was carried out using Web of Science, PubMed, EMBASE a... Read More about Meta-analysis demonstrates Gly482Ser variant of PPARGC1A is associated with components of metabolic syndrome within Asian populations..

Circulating levels of angiogenesis-related growth factors in breast cancer: a study to profile proteins responsible for tubule formation. (2017)
Journal Article
BARRON, G.A., GOUA, M., WAHLE, K.W.J. and BERMANO, G. 2017. Circulating levels of angiogenesis-related growth factors in breast cancer: a study to profile proteins responsible for tubule formation. Oncology reports [online], 38(3), pages 1886-1894. Available from: https://doi.org/10.3892/or.2017.5803

The present study exploited a versatile in vitro endothelial cell/fibroblast co-culture cell system to investigate the association between angiogenesis and breast cancer by comparing the capacity of plasma from women with breast cancer and age-matche... Read More about Circulating levels of angiogenesis-related growth factors in breast cancer: a study to profile proteins responsible for tubule formation..

Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression. (2015)
Journal Article
BARRON, G.A., GOUA, M., KURAOKA, I., BERMANO, G., IWAI, S. and KONG THOO LIN, P. 2015. Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression. Chemico-biological interactions [online], 242, pages 307-315. Available from: https://doi.org/10.1016/j.cbi.2015.10.017

Bisnaphthalimidopropyl diaminodicyclohexylmethane (BNIPDaCHM) bisintercalates to DNA and is a potential anti-cancer therapeutic. In an attempt to elucidate the mechanism(s) underlying the potential of BNIPDaCHM; earlier work was extended to investiga... Read More about Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression..

Can selenium supplementation modify oxidative stress in-vitro? (2015)
Journal Article
LEIGHTON, D., GOUA, M., DOLAN, E., BURGESS, K. and BERMANO, G. 2015. Can selenium supplementation modify oxidative stress in-vitro? A role for selenium supplementation in the prevention of cardiovascular disease. Journal of inflammation [online], 12(Supplement 1): abstracts from the 1st Annual meeting of the Scottish Society of Cytomics (SCC), 25 September 2014, Aberdeen, UK, article P7. Available from: https://doi.org/10.1186/1476-9255-12-S1-P7

Two thirds of the UK population are either overweight or obese (body mass index (BMI) 25-29.9 and >30 kg/m2 respectively) and are typically characterised by systemic oxidative stress (OS); deemed to play a key role in cardiovascular disease (CVD) dev... Read More about Can selenium supplementation modify oxidative stress in-vitro?.

Leptin inhibits proliferation of breast cancer cells at supraphysiological concentrations by inhibiting mitogen-activated protein kinase signaling. (2014)
Journal Article
WEICHHAUS, M., BROOM, J., WAHLE, K. and BERMANO, G. 2014. Leptin inhibits proliferation of breast cancer cells at supraphysiological concentrations by inhibiting mitogen-activated protein kinase signaling. Oncology letters [online], 8(1), pages 374-378. Available from: https://doi.org/10.3892/ol.2014.2085

Leptin is a hormone secreted by white fat tissue and signals the amount of overall body fat to the hypothalamus. The circulating concentration of leptin correlates with the level of obesity. Breast cancer risk is higher in obese postmenopausal women... Read More about Leptin inhibits proliferation of breast cancer cells at supraphysiological concentrations by inhibiting mitogen-activated protein kinase signaling..

Impact of high intensity interval training (HIIT) and/or selenium (Se) supplementation on oxidative stress and antioxidant status in active females. (2014)
Thesis
KEANE, K. 2014. Impact of high intensity interval training (HIIT) and/or selenium (Se) supplementation on oxidative stress and antioxidant status in active females. Robert Gordon University, MRes thesis.

Background: Cells continuously produce free radicals (FR) and reactive oxygen species (ROS) as part of metabolic processes. These free radicals are neutralized by an elaborate antioxidant defence system consisting of enzymes. An imbalance between ROS... Read More about Impact of high intensity interval training (HIIT) and/or selenium (Se) supplementation on oxidative stress and antioxidant status in active females..

Obesity and its health impact in Africa: a systematic review. (2012)
Journal Article
ADEBOYE, B., BERMANO, G. and ROLLAND, C., 2012. Obesity and its health impact in Africa: a systematic review. Cardiovascular journal of Africa [online], 23(9), pp. 512-521. Available from: https://doi.org/10.5830/CVJA-2012-040

Obesity and its association with co-morbidities in Africa are on the rise. This systematic review examines evidence of obesity and its association with co-morbidities within the African continent. Comparative studies conducted in Africa on adults 17... Read More about Obesity and its health impact in Africa: a systematic review..

Molecular aspects of the link between obesity, insulin resistance and breast cancer. (2010)
Thesis
WEICHHAUS, M.G. 2010. Molecular aspects of the link between obesity, insulin resistance and breast cancer. Robert Gordon University, PhD thesis.

Obesity is a multi-factorial metabolic disease, resulting in increased adipose tissue acquisition by the host. This disease increases the risk for developing co-morbidities, including Metabolic Syndrome and other disorders such as breast cancer. Obes... Read More about Molecular aspects of the link between obesity, insulin resistance and breast cancer..

Selenoprotein gene expression in an intestinal cell line during selenium depletion: a macroarray approach indicates effects on SelW and glutathione peroxidise 1. (2003)
Journal Article
PAGMANTIDIS, V., VILLETTE, S., BERMANO, G., BROOM, J., ARTHUR, J.R. and HESKETH, J.E. 2003. Selenoprotein gene expression in an intestinal cell line during selenium depletion: a macroarray approach indicates effects on SelW and glutathione peroxidise 1. Proceedings of the Nutrition Society [online], 62(1A), page 72A. Available from: https://doi.org/10.1017/S0029665103000776

The micronutrient selenium (Se) is incoprprated into a renage of selenoproteins involved in numerous biochemical processes within the body.