All Outputs (27)

Modulation of angiogenesis by inflammatory markers and the role of matrix metalloproteinases in an endothelial cell/fibroblast co-culture system. (2014)
Journal Article
BARRON, G.A., BORDET, E., GOUA, M. and BERMANO. G. 2014. Modulation of angiogenesis by inflammatory markers and the role of matrix metalloproteinases in an endothelial cell/fibroblast co-culture system. Current angiogenesis [online], 3(3), pages 152-163. Available from: https://doi.org/10.2174/2211552803666141113211829

Increased levels of inflammatory markers such as tumour necrosis factor-α (TNFα) and interleukin- 6 (IL-6) have been associated with formation of new blood vessels, or angiogenesis, and linked to chronic inflammation in obesity. This study aimed to e... Read More about Modulation of angiogenesis by inflammatory markers and the role of matrix metalloproteinases in an endothelial cell/fibroblast co-culture system..

In-vitro evaluation of the effect of polymer structure on uptake of novel polymer-insulin polyelectrolyte complexes by human epithelial cells. (2014)
Journal Article
IBIE, C., KNOTT, R. and THOMPSON, C.J. 2015. In-vitro evaluation of the effect of polymer structure on uptake of novel polymer-insulin polyelectrolyte complexes by human epithelial cells. International journal of pharmaceutics [online], 479(1), pages 103-117. Available from: https://doi.org/10.1016/j.ijpharm.2014.12.058

The biocompatibility and cellular uptake of polymer, insulin polyelectrolyte complexes (PECs) prepared using polyallylamine-based polymers was evaluated in-vitro using Caco-2 cell monolayers as a predictive model for human small intestinal epithelial... Read More about In-vitro evaluation of the effect of polymer structure on uptake of novel polymer-insulin polyelectrolyte complexes by human epithelial cells..

A mixed methods investigation into the use of non-technical skills by community and hospital pharmacists. (2014)
Journal Article
IRWIN, A. and WEIDMANN, A. 2015. A mixed methods investigation into the use of non-technical skills by community and hospital pharmacists. Research in social and administrative pharmacy [online], 11(5), pages 675-685. Available from: https://doi.org/10.1016/j.sapharm.2014.11.006

Background: Non-technical skills refer to the social and cognitive factors that may influence efficient and safe job performance. Non-technical skills are an important element of patient safety in a variety of health care disciplines, including surge... Read More about A mixed methods investigation into the use of non-technical skills by community and hospital pharmacists..

The electrochemical and statistical evaluation of isolation of mellitin and apamin from honey bee (Apis Mellifera) venom. (2014)
Journal Article
NGUYEN, H. V., HEGER, Z., KOMINKOVA, M., MICHALEK, P., GUMULEC, J., GURAN, R., PRIDAL, A., FERNANDEZ, C., HYNEK, D., ADAM, V. and KIZEK, R. 2015. The electrochemical and statistical evaluation of isolation of mellitin and apamin from honey bee (Apis Mellifera) venom. International journal of electrochemical science [online] , 10(2), pages 1249-1260. Available from: https://doi.org/10.1016/S1452-3981(23)05069-1

We present in this manuscript for the first time the electrochemical and statistical evaluation of FPLC isolation of mellitin and apamin from honey bee (Apis mellifera) venom. Venoms are extremely complex blends of diverse substances that target a my... Read More about The electrochemical and statistical evaluation of isolation of mellitin and apamin from honey bee (Apis Mellifera) venom..

Nutritional B vitamin deficiency alters the expression of key proteins associated with vascular smooth muscle cell proliferation and migration in the aorta of atherosclerotic apolipoprotein E null mice. (2014)
Journal Article
DUTHIE, S.J., BEATTIE, J.H., GORDON, M.-J., PIRIE, L.P., NICOL, F., REID, M.D., DUNCAN, G.J., CANTLAY, L., HORGAN, G. and MCNEIL, C.J. 2015. Nutritional B vitamin deficiency alters the expression of key proteins associated with vascular smooth muscle cell proliferation and migration in the aorta of atherosclerotic apolipoprotein E null mice. Genes and nutrition [online], 10(1), article 446. Available from: https://doi.org/10.1007/s12263-014-0446-y

Low B vitamin status is linked with human vascular disease. We employed a proteomic and biochemical approach to determine whether nutritional folate deficiency and/or hyperhomocysteinemia altered metabolic processes linked with atherosclerosis in Apo... Read More about Nutritional B vitamin deficiency alters the expression of key proteins associated with vascular smooth muscle cell proliferation and migration in the aorta of atherosclerotic apolipoprotein E null mice..

Kinetic and kinematic changes during a 30-repetition bout of the barbell clean. (2014)
Journal Article
SWINTON, P.A., SHITANSHI, D., DOLAN, E., BURGESS, K., SINGH, B. and ASPE, R. 2016. Kinetic and kinematic changes during a 30-repetition bout of the barbell clean. Journal of athletic enhancement [online], 5(1). Available from: https://doi.org/10.4172/2324-9080.1000220

The purpose of this stduy was to investigate the biomechanical effects of performing a large number of repetitions with a technically demanding exercise, as is recommended in many extreme conditioning programs. Sixteen trained male participants (age:... Read More about Kinetic and kinematic changes during a 30-repetition bout of the barbell clean..

General practitioner views of an electronic high-risk medicine proforma to facilitate information transfer. (2014)
Journal Article
RUSHWORTH, G.F., DIACK, L., RUDD, I.G. and STEWART, D. 2015. General practitioner views of an electronic high-risk medicine proforma to facilitate information transfer. International journal of clinical pharmacy [online], 37(1), pages 4-7. Available from: https://doi.org/10.1007/s11096-014-0033-8

Background The potential of warfarin related harm is increased if clinicians lack the full patient specific information to make informed decisions—an e-proforma has been developed to communicate this information on hospital discharge. Objective To de... Read More about General practitioner views of an electronic high-risk medicine proforma to facilitate information transfer..

Biodesalination: an emerging technology for targeted removal of Na+ and Cl− from seawater by cyanobacteria. (2014)
Journal Article
MINAS, K., KARUNAKARAN, E., BOND, T., GANDY, C., HONSBEIN, A., MADSEN, M., AMEZAGA, J., AMTMANN, A., TEMPLETON, M.R., BIGGS, C.A. and LAWTON, L. 2015. Biodesalination: an emerging technology for targeted removal of Na+ and Cl− from seawater by cyanobacteria. Desalination and water treatment [online], 55(10): selected papers presented at 2015 Desalination for the environment conference: clean water and energy, 11-15 May 2014, Limassol, Cyprus, pages 2647-2668. Available from: https://doi.org/10.1080/19443994.2014.940647

Although desalination by membrane processes is a possible solution to the problem of freshwater supply, related cost and energy demands prohibit its use on a global scale. Hence, there is an emerging necessity for alternative, energy and cost-efficie... Read More about Biodesalination: an emerging technology for targeted removal of Na+ and Cl− from seawater by cyanobacteria..

GPR55 deletion in mice leads to age-related ventricular dysfunction and impaired adrenoceptor-mediated inotropic responses. (2014)
Journal Article
WALSH, S.K., HECTOR, E.E., ANDREASSON, A.-C., JONSSON-RYLANDER, A.-C. and WAINWRIGHT, C. L. 2014. GPR55 deletion in mice leads to age-related ventricular dysfunction and impaired adrenoceptor-mediated inotropic responses. PLoS ONE [online], 9(10), article number e108999. Available from: https://doi.org/10.1371/journal.pone.0108999

G protein coupled receptor 55 (GPR55) is expressed throughout the body and, although its exact physiological function is unknown, studies have suggested that it has a role in the cardiovascular system. In particular, GPR55 has been proposed as mediat... Read More about GPR55 deletion in mice leads to age-related ventricular dysfunction and impaired adrenoceptor-mediated inotropic responses..

Oats and CVD risk markers: a systematic literature review. (2014)
Journal Article
THIES, F., MASSON, L.F., BOFFETTA, P. and KRIS-ETHERTON, P. 2014. Oats and CVD risk markers: a systematic literature review. British journal of nutrition [online], 112(S2), pages S19-S30. Available from: https://doi.org/10.1017/S0007114514002281

High consumption of whole-grain food such as oats is associated with a reduced risk of CVD and type 2 diabetes. The present study aimed to systematically review the literature describing long-term intervention studies that investigated the effects of... Read More about Oats and CVD risk markers: a systematic literature review..

Oats and bowel disease: a systematic literature review. (2014)
Journal Article
THIES, F., MASSON, L.F., BOFFETTA, P. and KRIS-ETHERTON, P. 2014. Oats and bowel disease: a systematic literature review. British journal of nutrition [online], 112 (S2), pages s31-S43. Available from: https://doi.org/10.1017/S0007114514002293

Whole-grain foods such as oats may protect against colorectal cancer and have benefits on inflammatory bowel disease and coeliac disease. The present study aimed to systematically review the literature describing intervention studies that investigate... Read More about Oats and bowel disease: a systematic literature review..

Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 h fast provides evidence of effects on genes regulating inflammation, apoptosis and energy metabolism. (2014)
Journal Article
ELLIOTT, R.M., DE ROOS, B., DUTHIE, S.J., BOUWMAN, F.G., RUBIO-ALIAGA, I., CROSLEY, L.K., MAYER, C., POLLEY, A.C., HEIM, C., COORT, S.L., EVELO, C.T., MULHOLLAND, F., DANIEL, H., MARIMAN, E.C. and JOHNSON, I.T. 2014. Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 h fast provides evidence of effects on genes regulating inflammation, apoptosis and energy metabolism. Genes and nutrition [online], 9(6), article 432. Available from: https://doi.org/10.1007/s12263-014-0432-4

There is growing interest in the potential health benefits of diets that involve regular periods of fasting. While animal studies have provided compelling evidence that feeding patterns such as alternate-day fasting can increase longevity and reduce... Read More about Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 h fast provides evidence of effects on genes regulating inflammation, apoptosis and energy metabolism..

A review on emerging contaminants in wastewaters and the environment: current knowledge, understudied areas and recommendations for future monitoring. (2014)
Journal Article
PETRIE, B., BARDEN, R., and KASPRZYK-HORDERN, B. 2015. A review on emerging contaminants in wastewaters and the environment: current knowledge, understudied areas and recommendations for future monitoring. Water research [online], 72, pages 3-27. Available from: https://doi.org/10.1016/j.watres.2014.08.053

This review identifies understudied areas of emerging contaminant (EC) research in wastewaters and the environment, and recommends direction for future monitoring. Non-regulated trace organic ECs including pharmaceuticals, illicit drugs and personal... Read More about A review on emerging contaminants in wastewaters and the environment: current knowledge, understudied areas and recommendations for future monitoring..

Experiences of supervision at practice placement sites. (2014)
Journal Article
DIACK, L., GIBSON, K., MUNRO, K. and STRATH, A. 2014. Experiences of supervision at practice placement sites. Education research international [online], 2014, Article ID 764519. Available from: https://doi.org/10.1155/2014/764519

Whilst placement supervision and clinical education programmes are of significant value in shaping the behaviours of undergraduate healthcare students, appropriate provisions which are efficacious to the learner are somewhat lacking, particularly for... Read More about Experiences of supervision at practice placement sites..

Waste to want: polymer nanocomposites using nanoclays extracted from oil based drilling mud waste. (2014)
Journal Article
ADEGBOTOLU, U.V., NJUGUNA, J., POLLARD, P. and YATES, K. 2014. Waste to want: polymer nanocomposites using nanoclays extracted from oil based drilling mud waste. IOP conference series: materials science and engineering [online], 64, Article 012023. Available from: https://doi.org/10.1088/1757-899X/64/1/012023

Due to the European Union (EU) waste frame work directive (WFD), legislations have been endorsed in EU member states such as UK for the Recycling of wastes with a vision to prevent and reduce landfilling of waste. Spent oil based drilling mud (drilli... Read More about Waste to want: polymer nanocomposites using nanoclays extracted from oil based drilling mud waste..

Development of consensus guidance to facilitate service redesign around pharmacist prescribing in UK hospital practice. (2014)
Journal Article
TONNA, A., MCCAIG, D., DIACK, L., WEST, B. and STEWART, D. 2014. Development of consensus guidance to facilitate service redesign around pharmacist prescribing in UK hospital practice. International journal of clinical pharmacy [online], 36(5), pages 1069-1076. Available from: https://doi.org/10.1007/s11096-014-9996-8

Background The last decade has seen a drive towards non-medical prescribing in the United Kingdom (UK). However, there is a dearth of any published literature on applying the principles of service redesign to support pharmacist prescribing in any sph... Read More about Development of consensus guidance to facilitate service redesign around pharmacist prescribing in UK hospital practice..

Electrochemical oxidation of acetyl salicylic acid and its voltammetric sensing in real samples at a sensitive edge plane pyrolytic graphite electrode modified with graphene. (2014)
Journal Article
KRUANETR, S., POLLARD, P., FERNANDEZ, C. and PRABHU, R. 2014. Electrochemical oxidation of acetyl salicylic acid and its voltammetric sensing in real samples at a sensitive edge plane pyrolytic graphite electrode modified with graphene. International journal of electrochemical science [online], 9(10), pages 5699-5711. Available from: https://doi.org/10.1016/S1452-3981(23)08199-3

We present in this manuscript for the first time the electrochemical oxidation of acetyl salicylic acid and its voltammetric sensing in real samples at a sensitive edge plane pyrolitic graphite electrode (EPPGE) modified with graphene. The electroche... Read More about Electrochemical oxidation of acetyl salicylic acid and its voltammetric sensing in real samples at a sensitive edge plane pyrolytic graphite electrode modified with graphene..

Alkaloids: an overview of their antibacterial, antibiotic-enhancing and antivirulence activities. (2014)
Journal Article
CUSHNIE, T.P.T., CUSHNIE, B. and LAMB, A.J. 2014. Alkaloids: an overview of their antibacterial, anibiotic-enhancing and antivirulence activities. International journal of antimicrobial agents [online], 44(5), pages 377-386. Available from: https://doi.org/10.1016/j.ijantimicag.2014.06.001

With reports of pandrug-resistant bacteria causing untreatable infections, the need for new antibacterial therapies is more pressing than ever. Alkaloids are a large and structurally diverse group of compounds that have served as scaffolds for import... Read More about Alkaloids: an overview of their antibacterial, antibiotic-enhancing and antivirulence activities..

UTP is not a biased agonist at human P2Y11 receptors. (2014)
Journal Article
MORROW, G.B., NICHOLAS, R.A. and KENNEDY, C. 2014. UTP is not a biased agonist at human P2Y11 receptors. Purinergic signalling [online], 10(4), pages 581-585. Available from: https://doi.org/10.1007/s11302-014-9418-3

Biased agonism describes a multistate model of G protein-coupled receptor activation in which each ligand induces a unique structural conformation of the receptor, such that the receptor couples differentially to G proteins and other intracellular pr... Read More about UTP is not a biased agonist at human P2Y11 receptors..

Assessing potential modifications to the activated sludge process to improve simultaneous removal of a diverse range of micropollutants. (2014)
Journal Article
PETRIE, B., MCADAM, E.J., LESTER, J.N. and CARTMELL, E. 2014. Assessing potential modifications to the activated sludge process to improve simultaneous removal of a diverse range of micropollutants. Water research [online], 62, pages 180-192. Available from: https://doi.org/10.1016/j.watres.2014.05.036

It is proposed that wastewater treatment facilities meet legislated discharge limits for a range of micropollutants. However, the heterogeneity of these micropollutants in wastewaters make removal difficult to predict since their chemistry is so dive... Read More about Assessing potential modifications to the activated sludge process to improve simultaneous removal of a diverse range of micropollutants..