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Development and single-laboratory validation of a UHPLC-MS/MS method for quantitation of microcystins and nodularin in natural water, cyanobacteria, shellfish and algal supplement tablet powders. (2017)
Journal Article
TURNER, A.D., WAACK, J., LEWIS, A., EDWARDS, C. and LAWTON, L. 2018. Development and single-laboratory validation of a UHPLC-MS/MS method for quantitation of microcystins and nodularin in natural water, cyanobacteria, shellfish and algal supplement tablet powders. Journal of chromatography B [online], 1074-1075, pages 111-123. Available from: https://doi.org/10.1016/j.jchromb.2017.12.032

A simple, rapid UHPLC-MS/MS method has been developed and optimised for the quantitation of microcystins and nodularin in wide variety of sample matrices. Microcystin analogues targeted were MC-LR, MC-RR, MC-LA, MC-LY, MC-LF, LC-LW, MC-YR, MC-WR, [As... Read More about Development and single-laboratory validation of a UHPLC-MS/MS method for quantitation of microcystins and nodularin in natural water, cyanobacteria, shellfish and algal supplement tablet powders..

Uptake and depuration of cyanotoxins in the common blue mussel Mytilus edulis. (2017)
Thesis
WAACK, J. 2017. Uptake and depuration of cyanotoxins in the common blue mussel Mytilus edulis. Robert Gordon University, PhD thesis.

Cyanobacteria produce a variety of secondary metabolites that possess - amongst other things - antifungal, antibacterial and antiviral properties. Being primary producers, they are also a vital component within the food web. However, certain strains... Read More about Uptake and depuration of cyanotoxins in the common blue mussel Mytilus edulis..

Effects of temperature and salinity on the production of cell biomass, chlorophyll-a and intra- and extracellular nodularins (NOD) and nodulopeptin 901 produced by Nodularia spumigena KAC 66. (2017)
Journal Article
HAMEED, S., LAWTON, L.A., EDWARDS, C., KHAN, A., FAROOQ, U. and KHAN, F.A. 2017. Effects of temperature and salinity on the production of cell biomass, chlorophyll-a and intra- and extracellular nodularins (NOD) and nodulopeptin 901 produced by Nodularia spumigena KAC 66. Journal of applied phycology [online], 29(4), pages 1801-1810. Available from: https://doi.org/10.1007/s10811-017-1115-5

Nodularia spumigena is one of the dominant toxic cyanobacteria which produce blooms in the Baltic Sea, a brackish water body, particularly in late summer. Nodularia spp. are known to produce hepatotoxic nodularins (NODs) and other bioactive peptides... Read More about Effects of temperature and salinity on the production of cell biomass, chlorophyll-a and intra- and extracellular nodularins (NOD) and nodulopeptin 901 produced by Nodularia spumigena KAC 66..

Hepatotoxic-microcystins in two drinking water reservoirs in the central region of Ghana. (2017)
Journal Article
ADDICO, G.N.D., LAWTON, L. and EDWARDS, C. 2017. Hepatotoxic-microcystins in two drinking water reservoirs in the central region of Ghana. Toxicology and forensic medicine [online], 2(1), pages 1-11. Available from: https://doi.org/10.17140/TFMOJ-2-111

Background: Microcystins are cyclic peptides containing seven amino acids with the condensation of two terminal amino acids of the linear peptide to form a cyclic compound. The cyclic nature of microcystins suggests that they are highly stable in wat... Read More about Hepatotoxic-microcystins in two drinking water reservoirs in the central region of Ghana..

Archaeological medicinal earths as antibacterial agents: the case of the Basel Lemnian sphragides. (2017)
Journal Article
PHOTOS-JONES, E., EDWARDS, C., HANER, F., LAWTON, L., KEAN, C., LEANORD, A. and PERDIKATSIS, V. 2017. Archaeological medicinal earths as antibacterial agents: the case of the Basel Lemnian sphragides. Geological society: special publications. Geology and medicine: historical connections [online], 452, pages 141-153. Available from: https://doi.org/10.1144/SP452.6

This paper presents the scientific investigation of three Lemnian sphragides (terra sigillata), a famed medicinal clay (earth) of antiquity, dated to the 16th-17th century, and presently in the collection of the Museum for the History of Pharmacy of... Read More about Archaeological medicinal earths as antibacterial agents: the case of the Basel Lemnian sphragides..