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Development and single-laboratory validation of a UHPLC-MS/MS method for quantitation of microcystins and nodularin in natural water, cyanobacteria, shellfish and algal supplement tablet powders. (2017)
Journal Article
TURNER, A.D., WAACK, J., LEWIS, A., EDWARDS, C. and LAWTON, L. 2018. Development and single-laboratory validation of a UHPLC-MS/MS method for quantitation of microcystins and nodularin in natural water, cyanobacteria, shellfish and algal supplement tablet powders. Journal of chromatography B [online], 1074-1075, pages 111-123. Available from: https://doi.org/10.1016/j.jchromb.2017.12.032

A simple, rapid UHPLC-MS/MS method has been developed and optimised for the quantitation of microcystins and nodularin in wide variety of sample matrices. Microcystin analogues targeted were MC-LR, MC-RR, MC-LA, MC-LY, MC-LF, LC-LW, MC-YR, MC-WR, [As... Read More about Development and single-laboratory validation of a UHPLC-MS/MS method for quantitation of microcystins and nodularin in natural water, cyanobacteria, shellfish and algal supplement tablet powders..

Pregnancy, prescription medicines and the potential risk of herb-drug interactions: a cross-sectional survey. (2017)
Journal Article
MCLAY, J.S., IZZATI, N., PALLIVALAPILA, A.R., SHETTY, A., PANDE, B., RORE, C., AL HAIL, M. and STEWART, D. 2017. Pregnancy, prescription medicines and the potential risk of herb-drug interactions: a cross-sectional survey. BMC complementary and alternative medicine [online], 17, article ID 543. Available from: https://doi.org/10.1186/s12906-017-2052-1

Background: - Pregnant women are routinely prescribed medicines while self-medicating with herbal natural products to treat predominantly pregnancy related conditions. The aim of this study was to assess the potential for herb-drug interactions (HDIs... Read More about Pregnancy, prescription medicines and the potential risk of herb-drug interactions: a cross-sectional survey..

Supporting shared decision-making and people's understanding of medicines: an exploration of the acceptability and comprehensibility of patient information. (2017)
Journal Article
GIBSON SMITH, K., BOOTH, J.L., STEWART, D., PFLEGER, S., MCIVER, L. and MACLURE, K. 2017. Supporting shared decision-making and people's understanding of medicines: an exploration of the acceptability and comprehensibility of patient information. Pharmacy practice [online], 15(4), article number 1082. Available from: https://doi.org/10.18549/PharmPract.2017.04.1082

Background: Patient information may assist in promoting shared decision-making, however it is imperative that the information presented is comprehensible and acceptable to the target audience. Objective: This study sought to explore the acceptability... Read More about Supporting shared decision-making and people's understanding of medicines: an exploration of the acceptability and comprehensibility of patient information..

Zinc-modified nanotransporter of doxorubicin for targeted prostate cancer delivery. (2017)
Journal Article
SKALICKOVA, S., LOFFELMANN, M., GARGULAK, M., KEPINSKA, M., DOCEKALOVA, M., UHLIROVA, D., STANKOVA, M., FERNANDEZ, C., MILNEROWICZ, H., RUTTKAY-NEDECKY, B. and KIZEK, R. 2017. Zinc-modified nanotransporter of doxorubicin for targeted prostate cancer delivery. Nanomaterials [online], 7(12), article ID 435. Available from: https://doi.org/10.3390/nano7120435

This work investigated the preparation of chitosan nanoparticles used as carriers for doxorubicin for targeted cancer delivery. Prepared nanocarriers were stabilized and functionalized via zinc ions incorporated into the chitosan nanoparticle backbon... Read More about Zinc-modified nanotransporter of doxorubicin for targeted prostate cancer delivery..

Novel vanillin derivatives: synthesis, anti-oxidant, DNA and cellular protection properties. (2017)
Journal Article
SCIPIONI, M., KAY, G., MEGSON, I. and KONG THOO LIN, P. 2017. Novel vanillin derivatives: synthesis, anti-oxidant, DNA and cellular protection properties. European journal of medicinal chemistry [online], 143, pages 745-754. Available from: https://doi.org/10.1016/j.ejmech.2017.11.072

Antioxidants have been the subject of intense research interest mainly due to their beneficial properties associated with human health and wellbeing. Phenolic molecules, such as naturally occurring Resveratrol and Vanillin, are well known for their a... Read More about Novel vanillin derivatives: synthesis, anti-oxidant, DNA and cellular protection properties..

Application of camelid heavy-chain variable domains (VHHs) in prevention and treatment of bacterial and viral infections. (2017)
Journal Article
WILKEN, L. and MCPHERSON, A. 2018. Application of camelid heavy-chain variable domains (VHHs) in prevention and treatment of bacterial and viral infections. International reviews of immunology [online], 37(1), pages 69-76. Available from: https://doi.org/10.1080/08830185.2017.1397657

Camelid heavy-chain variable domains (VHHs) are the smallest, intact, antigen-binding units to occur in nature. VHHs possess high degrees of solubility and robustness enabling generation of multivalent constructs with increased avidity - characterist... Read More about Application of camelid heavy-chain variable domains (VHHs) in prevention and treatment of bacterial and viral infections..

Unprecedented homotopy perturbation method for solving nonlinear equations in the enzymatic reaction of glucose in a spherical matrix. (2017)
Journal Article
SARANYA, K., MOHAN, V., KIZEK, R., FERNANDEZ, C. and RAJENDRAN, L. 2018. Unprecedented homotopy perturbation method for solving nonlinear equations in the enzymatic reaction of glucose in a spherical matrix. Bioprocess and biosystems engineering [online], 41(2), pages 281-294. Available from: https://doi.org/10.1007/s00449-017-1865-0

The theory of glucose-responsive composite membranes for the planar diffusion and reaction process is extended to a microsphere membrane. The theoretical model of glucose oxidation and hydrogen peroxide production in the chitosan-aliginate microspher... Read More about Unprecedented homotopy perturbation method for solving nonlinear equations in the enzymatic reaction of glucose in a spherical matrix..

A modified Delphi study to determine the level of consensus across the European Union on the structures, processes and desired outcomes of the management of polypharmacy in older people. (2017)
Journal Article
STEWART, D., GIBSON-SMITH, K., MACLURE, K., MAIR, A., ALONSO, A., CODINA, C., CITTADINI, A., FERNANDEZ-LLIMOS, F., FLEMING, G., GENNIMATA, D., GILLESPIE, U., HARRISON, C., JUNIUS-WALKER, U., KARDAS, P., KEMPEN, T., KINNEAR, M., LEWEK, P., MALVA, J., MCINTOSH, J., SCULLIN, C. and WIESE, B. 2017. A modified Delphi study to determine the level of consensus across the European Union on the structures, processes and desired outcomes of the management of polypharmacy in older people. PLOS one [online], 12(11), e0188348. Available from: https://doi.org/10.1371/journal.pone.0188348

Background:- Inappropriate use of multiple medicines (inappropriate polypharmacy) is a major challenge in older people with consequences of increased prevalence and severity of adverse drug reactions and interactions, and reduced medicines adherence.... Read More about A modified Delphi study to determine the level of consensus across the European Union on the structures, processes and desired outcomes of the management of polypharmacy in older people..

Heterogeneous Ti3SiC2@C-containing Na2Ti7O15 architecture for high-performance sodium storage at elevated temperatures. (2017)
Journal Article
ZOU, G., ZHANG, Q., FERNANDEZ, C., HUANG, G., HUANG, J. and PENG, Q. 2017. Heterogeneous Ti3SiC2@C-containing Na2Ti7O15 architecture for high-performance sodium storage at elevated temperatures. ACS nano [online], 11(12), pages 12219-12229. Available from: https://doi.org/10.1021/acsnano.7b05559

Rational design of heterogeneous electrode materials with hierarchical architecture is a potential approach to significantly improve their energy densities. Herein, we report a tailored microwave-assisted synthetic strategy to create heterogeneous hi... Read More about Heterogeneous Ti3SiC2@C-containing Na2Ti7O15 architecture for high-performance sodium storage at elevated temperatures..

Users' perceptions of interprofessional collaborative care during their cancer journeys'. (2017)
Journal Article
JOSEPH, S., BARNARD, S., MACDUFF, C., MOFFAT, M., WALKER, P. and DIACK, L. 2017. Users' perceptions of interprofessional collaborative care during their cancer journeys'. Journal of health science and education [online], 1(3), pages 1-11. Available from: http://escires.com/articles/Health-1-122.pdf

Purpose: The study aimed to construct narratives of journeys that cancer patients and their families experience and to investigate participants' perceptions of related interagency collaboration spanning any engagements with the National Health Servic... Read More about Users' perceptions of interprofessional collaborative care during their cancer journeys'..

Twelve tips for embedding human factors and ergonomics principles in healthcare education. (2017)
Journal Article
VOSPER, H., HIGNETT, S. and BOWIE, P. 2018. Twelve tips for embedding human factors and ergonomics principles in healthcare education. Medical teacher [online], 40(4), pages 357-363. Available from: https://doi.org/10.1080/0142159X.2017.1387240

Safety and improvement efforts in healthcare education and practice are often limited by inadequate attention to human factors/ergonomics (HFE) principles and methods. Integration of HFE theory and approaches within undergraduate curricula, postgradu... Read More about Twelve tips for embedding human factors and ergonomics principles in healthcare education..

A comprehensive systematic review of pharmacy perspectives on interprofessional education and collaborative practice. (2017)
Journal Article
EL-AWAISI, A., JOSEPH, S., EL HAJJ, M.S. and DIACK, L. 2018. A comprehensive systematic review of pharmacy perspectives on interprofessional education and collaborative practice. Research in social and administrative pharmacy [online], 14(10), pages 863-882. Available from: https://doi.org/10.1016/j.sapharm.2017.11.001

Introduction:- Pharmacists are key professionals in the collaborative working process and are integral members of the healthcare team. However, there is paucity of information regarding their perspectives towards interprofessional education (IPE) and... Read More about A comprehensive systematic review of pharmacy perspectives on interprofessional education and collaborative practice..

Hospital staff views of prescribing and discharge communication before and after electronic prescribing system implementation. (2017)
Journal Article
MILLS, P.R., WEIDMANN, A.E. and STEWART, D. 2017. Hospital staff views of prescribing and discharge communication before and after electronic prescribing system implementation. International journal of clinical pharmacy [online], 39(6), pages 1320-1330. Available from: https://doi.org/10.1007/s11096-017-0543-2

Background Electronic prescribing system implementation is recommended to improve patient safety and general practitioner's discharge information communication. There is a paucity of information about hospital staff perspectives before and after syst... Read More about Hospital staff views of prescribing and discharge communication before and after electronic prescribing system implementation..

Nasopharyngeal metagenomic deep sequencing data, Lancaster, UK, 2014-2015. (2017)
Journal Article
ATKINSON, K.V., BISHOP, L.A., RHODES, G., SALEZ, N., MCEWAN, N.R., HEGARTY, M.J., ROBEY, J., HARDING, N., WETHERELL, S., LAUDER, R.M., PICKUP, R.W., WILKINSON, M. and GATHERER, D. 2017. Nasopharyngeal metagenomic deep sequencing data, Lancaster, UK, 2014-2015. Scientific data [online], 4, article No. 170161. Available from: https://doi.org/10.1038/sdata.2017.161

Nasopharyngeal swabs were taken from volunteers attending a general medical practice and a general hospital in Lancaster, UK, and at Lancaster University, in the winter of 2014-2015. 51 swabs were selected based on high RNA yield and allocated to dee... Read More about Nasopharyngeal metagenomic deep sequencing data, Lancaster, UK, 2014-2015..

I can step outside my comfort zone. (2017)
Journal Article
MCFADYEN, M.C.E. and DIACK, L. 2017. I can step outside my comfort zone. Pharmacy [online], 5(4), article number 59. Available from: https://doi.org/10.3390/pharmacy5040059

On embarking upon such a multifactorial, professional degree as Pharmacy, students often find it difficult to meld the scientific- and practice-based components of the course. In final year of the undergraduate Masters of Pharmacy degree (MPharm) wit... Read More about I can step outside my comfort zone..

A summary of new findings on the biological effects of selenium in selected animal species: a critical review. (2017)
Journal Article
HOSNEDLOVA, B., KEPINSKA, M., SKALICKOVA, S., FERNANDEZ, C., RUTTKAY-NEDECKY, B., MALEVU, T.D., SOCHOR, J., BARON, M., MELCOVA, M., ZIDKOVA, J. and KIZEK, R. 2017. A summary of new findings on the biological effects of selenium in selected animal species: a critical review. International journal of molecular sciences [online], 18(10), paper ID 2209. Available from: https://doi.org/10.3390/ijms18102209

Selenium is an essential trace element important for many physiological processes, especially for the functions of immune and reproductive systems, metabolism of thyroid hormones, as well as antioxidant defense. Selenium deficiency is usually manifes... Read More about A summary of new findings on the biological effects of selenium in selected animal species: a critical review..

Seasonal variations of the digestive tract of the Eurasian beaver castor fiber. (2017)
Journal Article
BELZECKI, G., MILTKO, R., KOWALIK, B., DEMIASZKIEWICZ, A.W., LACHOWICZ, J., GIZEJEWSKI, Z., OBIDZINSKI, A., and MCEWAN, N.R. 2018. Seasonal variations of the digestive tract of the Eurasian beaver castor fiber. Mammal research [online], 63(1), pages 21-31. Available from: https://doi.org/10.1007/s13364-017-0337-x

Forage availability for wild rodents varies with season. In turn, the composition of food can affect morphometric parameters of the digestive tract. This study was performed in Eurasian beavers (Castor fiber) whose population was close to extinction... Read More about Seasonal variations of the digestive tract of the Eurasian beaver castor fiber..

DNA profiling of sperm cells by using micromanipulation and whole genome amplification. (2017)
Journal Article
THEUNISSEN, G.M.G., ROLF, B., GIBB, A. and JAGER, R. 2017. DNA profiling of sperm cells by using micromanipulation and whole genome amplification. Forensic science international: genetics supplement series [online], 6, pages e497-e499. Available from: https://doi.org/10.1016/j.fsigss.2017.09.183

The differential extraction method is based on separate lysis of vaginal cells and spermatozoa and was designed to prevent mixed DNA profiles from intimate swabs. However, DNA from the victim can still be present in the sperm fraction, and the suspec... Read More about DNA profiling of sperm cells by using micromanipulation and whole genome amplification..

Detection of in utero cannabis exposure by umbilical cord analysis. (2017)
Journal Article
KIM, J., DE CASTRO, A., LENDOIRO, E., CRUZ-LANDEIRA, A., LOPEZ-RIVADULLA, M. and CONCHEIRO, M. 2018. Detection of in utero cannabis exposure by umbilical cord analysis. Drug testing and analysis [online], 10(4), pages 636-643. Available from: https://doi.org/10.1002/dta.2307

According to the 2014 National Survey on Drug Use and Health, 5.3% of pregnant women smoked marijuana in the past month. This prevalence is expected to increase as a growing number of states and countries are now considering legalization. Although th... Read More about Detection of in utero cannabis exposure by umbilical cord analysis..

Exploring a problem-based learning approach in pharmaceutics. (2017)
Journal Article
MCKENZIE, B. and BROWN, A. 2017. Exploring a problem-based learning approach in pharmaceutics. Pharmacy [online], 5(3), article number 53. Available from: https://doi.org/10.3390/pharmacy5030053

Objective. The basis of this study was to explore the impact of the initiation of a Problem-Base Learning (PBL) approach within a second-year pharmaceutics degree on a Master of Pharmacy programme, introduced as a way of improving deep learning and t... Read More about Exploring a problem-based learning approach in pharmaceutics..