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All Outputs (6)

An investigation into the molecular mechanisms of hyperbaric oxygen using a human dermal microvascular endothelial cell line and a porcine retinal explant model. (2019)
Thesis
IWUAGWU, B.U. 2019. An investigation into the molecular mechanisms of hyperbaric oxygen using a human dermal microvascular endothelial cell line and a porcine retinal explant model. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

Diabetes is a debilitating metabolic condition with associated vascular complications that are a major cause of morbidity and mortality. Endothelial dysfunction is central to microvascular complications such as diabetic retinopathy (DR) and impaired... Read More about An investigation into the molecular mechanisms of hyperbaric oxygen using a human dermal microvascular endothelial cell line and a porcine retinal explant model..

Interprofessional, student-led intervention to improve insulin prescribing to patients in an Acute Surgical Receiving Unit. (2018)
Journal Article
TULLY, V., AL-SALTI, S., ARNOLD, A., BOTROS, S., CAMPBELL, I., FANE, R., ROWE, I., STRATH, A. and DAVEY, P. 2018. Interprofessional, student-led intervention to improve insulin prescribing to patients in an Acute Surgical Receiving Unit. BMJ open quality [online], 7(2), article number 000305. Available from: https://doi.org/10.1136/bmjoq-2017-000305

Our aim was to test the feasibility of interprofessional, workplace-based learning about improvement through a 4-week placement for one medical and two pharmacy final year students in an Acute Surgical Receiving Unit (ASRU). The target was insulin be... Read More about Interprofessional, student-led intervention to improve insulin prescribing to patients in an Acute Surgical Receiving Unit..

The effect of single nucleotide polymorphisms and metabolic substrates on the cellular distribution of mammalian BK channels. (2017)
Thesis
ADEYILEKA-TRACZ, B.A. 2017. The effect of single nucleotide polymorphisms and metabolic substrates on the cellular distribution of mammalian BK channels. Robert Gordon University, PhD thesis.

Humans are approximately 99% similar with inter-individual differences caused in part by single-nucleotide polymorphisms (SNPs), which poses a challenge for the effective treatment of disease. Bioinformatics resources can help to store and analyse ge... Read More about The effect of single nucleotide polymorphisms and metabolic substrates on the cellular distribution of mammalian BK channels..

Toward interprofessional learning and education: mapping common outcomes for prequalifying healthcare professional programs in the United Kingdom. (2017)
Journal Article
STEVEN, K., HOWDEN, S., MIRES, G., ROWE, I., LAFFERTY, N., ARNOLD, A. and STRATH, A. 2017. Toward interprofessional learning and education: mapping common outcomes for prequalifying healthcare professional programs in the United Kingdom. Medical teacher [online], 39(7), pages 720-744. Available from: https://doi.org/10.1080/0142159X.2017.1309372

Introduction: Interprofessional education (IPE) continues to be a key component in prequalifying health professional education, with calls for regulators to publish a joint statement regarding IPE outcomes. To date, the regulatory documents for healt... Read More about Toward interprofessional learning and education: mapping common outcomes for prequalifying healthcare professional programs in the United Kingdom..

Use of a three dimensional porcine retinal explant model to detect HIF1 alpha and targets for understanding diabetic retinopathy. (2017)
Presentation / Conference
IWUAGWU, B.U., CRUICKSHANK, S.F., ROWE, I. and KNOTT, R.M. 2017. Use of a three dimensional porcine retinal explant model to detect HIF1 alpha and targets for understanding diabetic retinopathy. Presented at the American Society for Biochemistry and Molecular Biology annual meeting 2017 (ASBMB'17), 22-26 April 2017, Chicago, USA.

Diabeticretinopathy (DR) is a major microvascular complication associated with diabetes mellitus and is a leading cause of blindness. Hypoxia and hyperglycemia are suggested to play crucial pathophysiological roles, but the exact mechanisms are compl... Read More about Use of a three dimensional porcine retinal explant model to detect HIF1 alpha and targets for understanding diabetic retinopathy..

Hypoxia-induced responses of porcine pulmonary veins. (2017)
Thesis
ARNOLD, A. 2017. Hypoxia-induced responses of porcine pulmonary veins. Robert Gordon University, PhD thesis.

The pulmonary vein (PV) constricts to hypoxia however little is known about the underlying mechanisms. Hypoxic PV constriction is proposed to recruit upstream capillary beds and optimise gas exchange in healthy humans and may play a role in high alti... Read More about Hypoxia-induced responses of porcine pulmonary veins..