Folate deficiency promotes differentiation of vascular smooth muscle cells without affecting the methylation status of regulated genes.
(2019)
Journal Article
KOLB, A.F., PETRIE, L., MAYER, C.D., PIRIE, L. and DUTHIE, S.J. 2019. Folate deficiency promotes differentiation of vascular smooth muscle cells without affecting the methylation status of regulated genes. Biochemical journal [online], 476(19), pages 2769-2795. Available from: https://doi.org/10.1042/BCJ20190275
Elevated serum homocysteine, an intermediate of cellular one-carbon metabolism, is an independent risk factor for cardiovascular disease (CVD). Folate deficiency increases serum homocysteine and may contribute to CVD progression. Vascular smooth musc... Read More about Folate deficiency promotes differentiation of vascular smooth muscle cells without affecting the methylation status of regulated genes..