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All Outputs (15)

Crafting stories from verbatim data in hermeneutic phenomenology is trustworthy and useful. (2016)
Journal Article
CROWTHER, S. 2016. Crafting stories from verbatim data in hermeneutic phenomenology is trustworthy and useful. International journal of qualitative methods [online], 15(1), abstracts, oral presentations from the Qualitative methods conference (QM), 1-3 May 2016, Glasgow, UK, page 10. Available from: https://doi.org/10.1177/1609406916672113

Abstract of the oral presentation given at the qualitative methods conferece (QM) 1 - 3 May 2016, Glasgow, UK.

Can selenium supplementation modify oxidative stress in-vitro? (2015)
Journal Article
LEIGHTON, D., GOUA, M., DOLAN, E., BURGESS, K. and BERMANO, G. 2015. Can selenium supplementation modify oxidative stress in-vitro? A role for selenium supplementation in the prevention of cardiovascular disease. Journal of inflammation [online], 12(Supplement 1): abstracts from the 1st Annual meeting of the Scottish Society of Cytomics (SCC), 25 September 2014, Aberdeen, UK, article P7. Available from: https://doi.org/10.1186/1476-9255-12-S1-P7

Two thirds of the UK population are either overweight or obese (body mass index (BMI) 25-29.9 and >30 kg/m2 respectively) and are typically characterised by systemic oxidative stress (OS); deemed to play a key role in cardiovascular disease (CVD) dev... Read More about Can selenium supplementation modify oxidative stress in-vitro?.

Pro's and con's of the stepped wedge design in cluster randomised trials of quality improvement interventions: two current examples. (2013)
Journal Article
DREISCHULTE, T., GRANT, A., DONNAN, P. and GUTHRIE, B. 2013. Pro's and con's of the stepped wedge design in cluster randomised trials of quality improvement interventions: two current examples. Trials [online], 14(Supplement 1): oral and poster presentations of the 2nd Clinical trials methodology conference 2013: methodology matters, 18-19 November 2013, Edinburgh, UK, abstract O87. Available from: https://doi.org/10.1186/1745-6215-14-S1-O87

The stepped wedge design, under which all trial participants receive the intervention but the order in which the intervention is received is randomised, is potentially useful to rigorously evaluate organisational interventions to improve quality and... Read More about Pro's and con's of the stepped wedge design in cluster randomised trials of quality improvement interventions: two current examples..

Parallel process evaluation using a proposed framework for the design and reporting of process evaluations for cluster-randomised trials of complex interventions. (2013)
Journal Article
GRANT, A., DREISCHULTE, T. and GUTHRIE, B. 2013. Parallel process evaluation using a proposed framework for the design and reporting of process evaluations for cluster-randomised trials of complex interventions. Trials [online], 14(Supplement 1): oral and poster presentations from the 2nd Clinical trials methodology conference 2013: methodology matters, 18-19 November 2013, Edinburgh, UK, Article O88. Available from: https://doi.org/10.1186/1745-6215-14-S1-O88

Process evaluations are recommended to open the 'black box' of complex interventions evaluated in trials, but there is limited guidance to help with design, with most guidance focused on the use of qualitative methods rather than processes to evaluat... Read More about Parallel process evaluation using a proposed framework for the design and reporting of process evaluations for cluster-randomised trials of complex interventions..

Assessing the significance of ethnicity on VLCD induced weight loss and outcomes at 1 year follow up. (2012)
Journal Article
ROLLAND, C., MULHOLLAND, Y., HALLAM, C., LULA, S., DYSON, L. and BROOM, I. 2012. Assessing the significance of ethnicity on VLCD induced weight loss and outcomes at 1 year follow up. Obesity facts [online], 5(Supplement 1), page 94. Available at: https://doi.org/10.1159/000178128

Introduction: Few studies have examined the relationship between ethnicity and longer-term outcomes following a very-low-calorie diet (VLCD).

A comparison of weight loss outcomes in Black and Caucasian women following a very-low calorie diet (VLCD). (2012)
Journal Article
ROLLAND, C., MULHOLLAND, Y., HALLAM, C., LULA, S., DYSON, L. and BROOM, I. 2012. A comparison of weight loss outcomes in Black and Caucasian women following a very-low calorie diet (VLCD). Obesity facts [online], 5(Supplement 1), page 94. Available from: https://doi.org/10.1159/000178128

Introduction: Few studies have examined the significance of ethnicity on weight loss responses and overall health benefits following a VLCD.

Improving recruitment to clinical trials with a register of a million patients who agree to the use of their clinical records for research in the Scottish Health Research Register (SHARE). (2011)
Journal Article
SULLIVAN, F.M., TREWEEK, S., GRANT, A., DALY, F., NICOLSON, D., MCKINSTRY, B., HANLEY, J., URE, J. and SHEIKH, A. 2011. Improving recruitment to clinical trials with a register of a million patients who agree to the use of their clinical records for research in the Scottish Health Research Register (SHARE). Trials [online], 12(Supplement 1): oral and poster presentations from the 2011 Clinical trials methodology conference, 4-5 October 2011, Bristol, UK, abstract A115. Available from: https://doi.org/10.1186/1745-6215-12-S1-A115

The UK's technical ability to identify people eligible for medical research is not yet matched by a practical capability to approach them directly to ask them to consider participation in those studies. The consequence is that recruitment to research... Read More about Improving recruitment to clinical trials with a register of a million patients who agree to the use of their clinical records for research in the Scottish Health Research Register (SHARE)..

Selenoprotein gene expression in an intestinal cell line during selenium depletion: a macroarray approach indicates effects on SelW and glutathione peroxidise 1. (2003)
Journal Article
PAGMANTIDIS, V., VILLETTE, S., BERMANO, G., BROOM, J., ARTHUR, J.R. and HESKETH, J.E. 2003. Selenoprotein gene expression in an intestinal cell line during selenium depletion: a macroarray approach indicates effects on SelW and glutathione peroxidise 1. Proceedings of the Nutrition Society [online], 62(1A), page 72A. Available from: https://doi.org/10.1017/S0029665103000776

The micronutrient selenium (Se) is incoprprated into a renage of selenoproteins involved in numerous biochemical processes within the body.

Systematic review of exercise and the long-term outcomes of the treatment for obesity. (2002)
Journal Article
BROWN, T.J., AVENELL, A., BROOM, J., SMITH, W.C.S., JUNG, R., CAMPBELL, M.K. and GRANT, A.M. 2002. Systematic review of exercise and the long-term outcomes of the treatment for obesity. Proceedings of the Nutrition Society [online], 61(3A), page 154A. Available from: https://doi.org/10.1017/S0029665102000289

We systematically reviewed randomised controlled trials (RCTs) of obesity treatments in adults and assessed long term effects on weight and risk factors for disease.

Stimulation of colorectal tumour protein synthesis, in vivo, by nutritional support. (1990)
Journal Article
HEYS, S.D., PARK, K.G.M., McNURLAN, M.A., MILNE, E., KEENAN, R.A., MILLER, J.D.B., BROOM, J., EREMIN, O. and GARLICK, P.J. 1990. Stimulation of colorectal tumour protein synthesis, in vivo, by nutritional support. Proceedings of the Nutrition Society [online], 49(2), page 165A. Available from: https://doi.org/10.1079/PNS19900038

Malignant disease is frequently accompanied by weight loss and malnutrition, which are associated with an increase in patient mortality and morbidity.

A study of the time course of fructose-2, 6-bisphosphate production in a septic mouse model. (1986)
Journal Article
HEPBURN, D., BROOM, J. and SMITH, D.J. 1986. A study of the time course of fructose-2, 6-bisphosphate production in a septic mouse model. Proceedings of the Nutrition Society [online], 45(1), page 33A. Available from: https://doi.org/10.1079/PNS19860044

Where sepsis occurs in the post-surgical period, mortality rates tend to be high. In sepsis, metabolism is grossly disrupted with glucose becoming the preferred fuel for energy provision even where ketogenesis has been promoted.

The effects of postoperative metabolic support on lipolytic rates in patients undergoing elective abdominal surgery. (1986)
Journal Article
BROOM, J., BRACKENRIDGE, I.E., SIMPSON, E., MILLER, J.D.B. and MORRISON, I. 1986. The effects of postoperative metabolic support on lipolytic rates in patients undergoing elective abdominal surgery. Proceedings of the Nutrition Society [online], 45(1), page 20A. Available from: https://doi.org/10.1079/PNS19860042

The metabolic response to trauma is associated with mobilization of energy substrates including fat or fat-derived substrates.

Biochemical adaptations in early starvation: observations on sex difference. (1978)
Journal Article
BROOM, J., FLECK, A., DAVIDSON, D.F., ROSENBURG, C. and DURNIN, J.V.G.A. 1978. Biochemical adaptations in early starvation: observations on sex difference. Proceedings of the Nutrition Society [online], 37(3), page 92A. Available from: https://doi.org/10.1079/PNS19780048

Twenty-two students, eleven male and eleven female, volunteered to fast for 3 d. Twenty-four hour urine collections were obtained over the period of study, and total nitrogen, urea, and 3-hydroxybutyrate (3-OH-butyrate) were determined in each.

Protein synthesis in the rat liver after fracture of the femur. (1974)
Journal Article
KHAN, S.N., TILSTONE, W.J., FLECK, A. and BROOM, I. 1974. Protein synthesis in the rat liver after fracture of the femur. Proceedings of the Nutrition Society [online], 33(3), pages 93A-94A. Available from: https://doi.org/10.1079/PNS19740058

Moderate to severe trauma is accompanied by two characteristic responses in plasma protein concentration, namely an increase in levels of acute phase reactants and a fall in albumin (Cuthbertson & Tompsett, 1935; Oweb, 1967).