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All Outputs (5)

Genome-guided bioprospecting for novel antibiotic lead compounds. (2023)
Thesis
AWOLOPE, O.K. 2023. Genome-guided bioprospecting for novel antibiotic lead compounds. Robert Gordon University, PhD thesis. Hosted on OpenAIR [online]. Available from: https://doi.org/10.48526/rgu-wt-1987833

Antimicrobial resistance continues to pose a threat to health and wellbeing. Unmitigated, it is predicted to be the leading cause of death by 2050. Hence, the sustained development of novel antibiotics is crucial. As over 60% of licensed antibiotics... Read More about Genome-guided bioprospecting for novel antibiotic lead compounds..

De novo genome assembly and analysis unveil biosynthetic and metabolic potentials of Pseudomonas fragi A13BB. [Dataset] (2021)
Data
AWOLOPE, O.K., O'DRISCOLL, N.H., DI SALVO, A. and LAMB, A.J. 2021. De novo genome assembly and analysis unveil biosynthetic and metabolic potentials of Pseudomonas fragi A13BB. [Dataset]. BMC genomic data [online], 22, article number 15. Available from: https://doi.org/10.1186/s12863-021-00969-0

Objectives; The role of rhizosphere microbiome in supporting plant growth under biotic stress is well documented. Rhizobacteria ward off phytopathogens through various mechanisms including antibiosis. We sought to recover novel antibiotic-producing b... Read More about De novo genome assembly and analysis unveil biosynthetic and metabolic potentials of Pseudomonas fragi A13BB. [Dataset].

The complete genome sequence of Hafnia alvei A23BA: a potential antibiotic-producing rhizobacterium. [Dataset] (2021)
Data
AWOLOPE, O.K., O'DRISCOLL, N.H., DI SALVO, A. and LAMB, A.J. 2021. The complete genome sequence of Hafnia alvei A23BA: a potential antibiotic-producing rhizobacterium. [Dataset]. BMC research notes [online], 14, article number 8. Available from: https://doi.org/10.1186/s13104-020-05418-2

Objectives: The urgent need for novel antibiotics cannot be overemphasized. Hafnia alvei A23BA was isolated from plant rhizosphere as part of an effort to recover novel antibiotic-producing bacterial strains from soil samples. The genome of the isola... Read More about The complete genome sequence of Hafnia alvei A23BA: a potential antibiotic-producing rhizobacterium. [Dataset].

The design, synthesis and evaluation of selective, non invasive imaging agents for atherosclerotic plaque. (2017)
Thesis
JESUDOSS, J.R. 2017. The design, synthesis and evaluation of selective, non invasive imaging agents for atherosclerotic plaque. Robert Gordon University, MPhil thesis.

The aim of this research study was the synthesis of an imaging agent, which could be used to non-invasively image atherosclerotic plaques via MRI. In order to achieve this, a library of peptide substrates designed to be substrate specific for either... Read More about The design, synthesis and evaluation of selective, non invasive imaging agents for atherosclerotic plaque..

Examination of the antibacterial activities of some semi-synthetic chalcone-derivatives alone and in combination with polymyxin B. (2013)
Thesis
MEDU, E.O. 2013. Examination of the antibacterial activities of some semi-synthetic chalcone-derivatives alone and in combination with polymyxin B. Robert Gordon University, PhD thesis.

Bacterial resistance is an increasing challenge across the world, which means that there is an urgent need for the rational development of antibacterial compounds that have either novel or multiple mechanisms of action. This study demonstrated that t... Read More about Examination of the antibacterial activities of some semi-synthetic chalcone-derivatives alone and in combination with polymyxin B..