Skip to main content

Research Repository

Advanced Search

DNA profiling of single sperm cells and single skin flakes in forensics using micromanipulation and whole genome amplification. (2020)
Thesis
THEUNISSEN, G.M.G. 2020. DNA profiling of single sperm cells and single skin flakes in forensics using micromanipulation and whole genome amplification. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

In forensic DNA profiling, the occurrence of complex mixed profiles is currently a common issue. Cases involving intimate swabs or skin flake tape liftings are prone to mixed profiles, because of more than one donor contributing to a DNA sample. By D... Read More about DNA profiling of single sperm cells and single skin flakes in forensics using micromanipulation and whole genome amplification..

Synthesis of novel vanillin derivatives: study of their antioxidant and potential neuroprotective properties. (2019)
Thesis
SCIPIONI, M. 2019. Synthesis of novel vanillin derivatives: study of their antioxidant and potential neuroprotective properties. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

Vanillin (4-hydroxy-3-methoxybenzaldehyde) is a naturally-occurring phenolic compound, forming the main component of the bean and pod of vanilla orchids. It is widely used as a flavouring agent in food and drinks, and as a preservative in the cosmeti... Read More about Synthesis of novel vanillin derivatives: study of their antioxidant and potential neuroprotective properties..

The potential application of rapeseed pomace extracts in the prevention and treatment of neurodegenerative diseases. (2019)
Thesis
POHL, F. 2019. The potential application of rapeseed pomace extracts in the prevention and treatment of neurodegenerative diseases. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

Rapeseed pomace (RSP) is the waste/by-product obtained after edible oil production from Brassica napus and is currently used as animal feed. In an attempt to revalorize this by-product as a potential nutraceutical for the treatment or prevention of n... Read More about The potential application of rapeseed pomace extracts in the prevention and treatment of neurodegenerative diseases..

Sustainable treatment of oil contaminated waste: oil-based mud (OBM) drill cuttings and soil. (2018)
Thesis
NWINEE, S.A. 2018. Sustainable treatment of oil contaminated waste: oil-based mud (OBM) drill cuttings and soil. Robert Gordon University, PhD thesis.

Environmental pollution from oilfield drilling waste poses potential hazards which can lead to ecological imbalance. The predominant pollutant from oilfield waste is petroleum hydrocarbons. Some effects of petroleum hydrocarbon contamination in soil... Read More about Sustainable treatment of oil contaminated waste: oil-based mud (OBM) drill cuttings and soil..

Targeting histone deacetylase (HDACs) enzymes with novel bisnaphthalimidopropyl derivatives (BNIPs) as alternative breast cancer therapies. (2018)
Thesis
KOPSIDA, M. 2018. Targeting histone deacetylase (HDACs) enzymes with novel bisnaphthalimidopropyl derivatives (BNIPs) as alternative breast cancer therapies. Robert Gordon University, PhD thesis.

Breast cancer is the most commonly occurring cancer in women, with incidence rates approaching 1.38 million cases per year worldwide. Over the last few decades, there have been numerous attempts to develop, synthesise and advance into the clinic nove... Read More about Targeting histone deacetylase (HDACs) enzymes with novel bisnaphthalimidopropyl derivatives (BNIPs) as alternative breast cancer therapies..

Novel bisnaphthalimidopropyl polyamine derivatives: their mode of action in a breast cancer cell system. (2010)
Thesis
BARRON, G. 2010. Novel bisnaphthalimidopropyl polyamine derivatives: their mode of action in a breast cancer cell system. Robert Gordon University, PhD thesis.

The synthesis and characterisation of novel bisnaphthalimidopropyl polyamine (BNIPP) derivatives has gained pace over the last couple of years, as they have enhanced aqueous solubility without loss of biological activity in contrast to parent bisnaph... Read More about Novel bisnaphthalimidopropyl polyamine derivatives: their mode of action in a breast cancer cell system..

The characterisation and identification of body fluid proteins for forensic purposes. (2010)
Thesis
VINCINI, L. 2010. The characterisation and identification of body fluid proteins for forensic purposes. Robert Gordon University, PhD thesis.

Advances in DNA technology have led to the extremely sensitive and rapid analysis methods used in forensic science. It can often be crucial to a criminal case to unequivocally identify the body fluid source of DNA. This is of particular importance in... Read More about The characterisation and identification of body fluid proteins for forensic purposes..

The use of novel poly(allylamine) based amphiphilic polymers for drug delivery. (2010)
Thesis
HOSKINS, C. 2010. The use of novel poly(allylamine) based amphiphilic polymers for drug delivery. Robert Gordon University, PhD thesis.

Fourteen novel comb shaped amphiphilic polymers were successfully synthesised to determine the effect of polymer architecture on the potential of these amphiphilic polymers for hydrophobic drug delivery. Polyallylamine (PAA) was grafted with four dif... Read More about The use of novel poly(allylamine) based amphiphilic polymers for drug delivery..

The effect of CLAs on the expression of PKC isoforms and cell viability in breast cancer cell lines. (2008)
Thesis
CRABB-WYKE, R. 2008. The effect of CLAs on the expression of PKC isoforms and cell viability in breast cancer cell lines. Robert Gordon University, MPhil thesis.

Breast tumours make up 15% of the total cancer burden in the UK and around 8% of the total number of cancer related deaths. Protein kinase C (PKC) isoforms have been shown to be strongly modulated in many androgen sensitive tumour cell lines. Increas... Read More about The effect of CLAs on the expression of PKC isoforms and cell viability in breast cancer cell lines..