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All Outputs (5)

The design and synthesis of novel pro-drugs for the treatment of nephropathic cystinosis. (2015)
Thesis
BAHMED, A. 2015. The design and synthesis of novel pro-drugs for the treatment of nephropathic cystinosis. Robert Gordon University, PhD thesis.

Cystinosis is a metabolic disorder characterised by the abnormal accumulation of the amino acid cystine in cells leading to a slow destruction of all major organs. If patients diagnosed with cystinosis are untreated, death due to kidney failure ensue... Read More about The design and synthesis of novel pro-drugs for the treatment of nephropathic cystinosis..

Development and characterization of biodegradable microspheres containing selected antimycobacterials. (1998)
Thesis
BAIN, D.F. 1998. Development and characterization of biodegradable microspheres containing selected antimycobacterials. Robert Gordon University, PhD thesis.

Prolonged therapy required to effectively treat mycobacterial infection frequently results in severe dose-limiting side-effects and drug resistance due to patient non-compliance with protracted dosage regimens. Biodegradable poly-a-hydroxy acid micro... Read More about Development and characterization of biodegradable microspheres containing selected antimycobacterials..

Preparation of novel modified-release dosage forms of diclofenac sodium and ibuprofen. (1997)
Thesis
SUJJA-AREEVATH, J. 1997. Preparation of novel modified-release dosage forms of diclofenac sodium and ibuprofen. Robert Gordon University, PhD thesis.

Mini-matrix multiple unit dosage forms (MUDFs) of diclofenac sodium and S(+) ibuprofen have been prepared. Normal tabletting techniques were used to form the mini-matrices prior to their enclosure in hard gelatin capsules. Four natural hydrophilic gu... Read More about Preparation of novel modified-release dosage forms of diclofenac sodium and ibuprofen..

Enhanced microcomputer operation of X-ray diffractometers and subsequent applications. (1992)
Thesis
SUTHERLAND, N.S. 1992. Enhanced microcomputer operation of X-ray diffractometers and subsequent applications. Robert Gordon University, PhD thesis.

The work described within this thesis is mainly concerned with the solution and refinement of the molecular structures of a variety of novel compounds. A number of X-ray and neutron diffractometers have been utilised for the analysis of specific comp... Read More about Enhanced microcomputer operation of X-ray diffractometers and subsequent applications..

The synthesis and structural examination of 3alpha, 5-cyclo-5alpha-androstane steroids. (1992)
Thesis
GIBB, B.C. 1992. The synthesis and structural examination of 3alpha, 5-cyclo-5alpha-androstane steroids. Robert Gordon University, PhD thesis.

The work described in this thesis is based on the synthesis and structural examination of several cyclosteroids. The a-aromatic steroid 3a, 5-cyclo-5c-androstan-6beta-ol- 17-one was used as a lead compound in an attempt to produce, in particular, the... Read More about The synthesis and structural examination of 3alpha, 5-cyclo-5alpha-androstane steroids..