Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 h fast provides evidence of effects on genes regulating inflammation, apoptosis and energy metabolism.

Elliott, R. M.; de Roos, B.; Duthie, S. J.; Bouwman, F. G.; Rubio-Aliaga, I.; Crosley, L. K.; Mayer, C.; Polley, A. C.; Heim, C.; Coort, S. L.; Evelo, C. T.; Mulholland, F.; Daniel, H.; Mariman, E. C.; Johnson, I. T.

doi:10.1007/s12263-014-0432-4

All Outputs (2)

Nutritional B vitamin deficiency alters the expression of key proteins associated with vascular smooth muscle cell proliferation and migration in the aorta of atherosclerotic apolipoprotein E null mice. (2014)
Journal Article
DUTHIE, S.J., BEATTIE, J.H., GORDON, M.-J., PIRIE, L.P., NICOL, F., REID, M.D., DUNCAN, G.J., CANTLAY, L., HORGAN, G. and MCNEIL, C.J. 2015. Nutritional B vitamin deficiency alters the expression of key proteins associated with vascular smooth muscle cell proliferation and migration in the aorta of atherosclerotic apolipoprotein E null mice. Genes and nutrition [online], 10(1), article 446. Available from: https://doi.org/10.1007/s12263-014-0446-y

Low B vitamin status is linked with human vascular disease. We employed a proteomic and biochemical approach to determine whether nutritional folate deficiency and/or hyperhomocysteinemia altered metabolic processes linked with atherosclerosis in Apo... Read More about Nutritional B vitamin deficiency alters the expression of key proteins associated with vascular smooth muscle cell proliferation and migration in the aorta of atherosclerotic apolipoprotein E null mice..

Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 h fast provides evidence of effects on genes regulating inflammation, apoptosis and energy metabolism. (2014)
Journal Article
ELLIOTT, R.M., DE ROOS, B., DUTHIE, S.J., BOUWMAN, F.G., RUBIO-ALIAGA, I., CROSLEY, L.K., MAYER, C., POLLEY, A.C., HEIM, C., COORT, S.L., EVELO, C.T., MULHOLLAND, F., DANIEL, H., MARIMAN, E.C. and JOHNSON, I.T. 2014. Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 h fast provides evidence of effects on genes regulating inflammation, apoptosis and energy metabolism. Genes and nutrition [online], 9(6), article 432. Available from: https://doi.org/10.1007/s12263-014-0432-4

There is growing interest in the potential health benefits of diets that involve regular periods of fasting. While animal studies have provided compelling evidence that feeding patterns such as alternate-day fasting can increase longevity and reduce... Read More about Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 h fast provides evidence of effects on genes regulating inflammation, apoptosis and energy metabolism..