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Preconception knowledge, beliefs and behaviours among people of reproductive age: a systematic review of qualitative studies. (2023)
Journal Article
WELSHMAN, H., DOMBROWSKI, S., GRANT, A., SWANSON, V., GOUDREAU, A. and CURRIE, S. 2023. Preconception knowledge, beliefs and behaviours among people of reproductive age: a systematic review of qualitative studies. Preventive medicine [online], In Press, article number 107707. Available from: https://doi.org/10.1016/j.ypmed.2023.107707

The health of parents before pregnancy influences the short- and long-term health of their offspring. This systematic review explored the preconception knowledge, beliefs and behaviours held by women and men of childbearing age. Databases were search... Read More about Preconception knowledge, beliefs and behaviours among people of reproductive age: a systematic review of qualitative studies..

Implementation frameworks for polypharmacy management within healthcare organisations: a scoping review. (2023)
Journal Article
AL BULUSHI, S., MCINTOSH, T., GRANT, A., STEWART, D. and CUNNINGHAM, S. 2023. Implementation frameworks for polypharmacy management within healthcare organisations: a scoping review. International journal of clinical pharmacy [online], 15(2), pages 342-354. Available from: https://doi.org/10.1007/s11096-023-01534-8

Several guidelines support polypharmacy management in individual patients. More organisational-level focus is needed on the use of implementation frameworks. The aim of this scoping review was to characterise the peer-reviewed literature on implement... Read More about Implementation frameworks for polypharmacy management within healthcare organisations: a scoping review..

A journey of self-discovery and transformation: a theoretical and comprehensive evaluation of the Queen's Nursing Institute Scotland community development programme. (2023)
Journal Article
GRANT, A., MACIVER, E., ADAMS, N., TEODOROWSKI, P. and KENNEDY, C. 2023. A journey of self-discovery and transformation: a theoretical and comprehensive evaluation of the Queen's Nursing Institute Scotland community development programme. Journal of advanced nursing [online], 79(6), pages 2200-2210. Available from: https://doi.org/10.1111/jan.15552

The aim of this study was to evaluate adoption, implementation and maintenance of the Queen's Nursing Institute Scotland development programme. This was undertaken through a comprehensive, longitudinal, qualitative evaluation. Participants from the f... Read More about A journey of self-discovery and transformation: a theoretical and comprehensive evaluation of the Queen's Nursing Institute Scotland community development programme..

Basic versus biofeedback-mediated intensive pelvic floor muscle training for women with urinary incontinence: the OPAL RCT. (2020)
Journal Article
HAGEN, S., BUGGE, C., DEAN, S.G. et al. 2020. Basic versus biofeedback-mediated intensive pelvic floor muscle training for women with urinary incontinence: the OPAL RCT. Health technology assessment [online], 24(70), pages 1-144. Available from: https://doi.org/10.3310/hta24700

Background: Urinary incontinence affects one in three women worldwide. Pelvic floor muscle training is an effective treatment. Electromyography biofeedback (providing visual or auditory feedback of internal muscle movement) is an adjunct that may imp... Read More about Basic versus biofeedback-mediated intensive pelvic floor muscle training for women with urinary incontinence: the OPAL RCT..

Designing process evaluations using case study to explore the context of complex interventions evaluated in trials. (2020)
Journal Article
GRANT, A., BUGGE, C. and WELLS, M. 2020. Designing process evaluations using case study to explore the context of complex interventions evaluated in trials. Trials [online], 21, article number 982. Available from: https://doi.org/10.1186/s13063-020-04880-4

Process evaluations are an important component of an effectiveness evaluation as they focus on understanding the relationship between interventions and context to explain how and why interventions work or fail, and whether they can be transferred to... Read More about Designing process evaluations using case study to explore the context of complex interventions evaluated in trials..

Pharmacist and data-driven quality improvement in primary care (P-DQIP): a qualitative study of anticipated implementation factors informed by the theoretical domains framework. (2020)
Journal Article
TANG, J., TOMA, M., GRAY, N.M., DELVAUX, J., GUTHRIE, B., GRANT, A., DUNCAN, E.M. and DREISCHULTE, T. 2020. Pharmacist and data-driven quality improvement in primary care (P-DQIP): a qualitative study of anticipated implementation factors informed by the theoretical domains framework. BMJ open [online], 10(2), article ID e033574. Available from: https://doi.org/10.1136/bmjopen-2019-033574

Objectives: The quality and safety of drug therapy in primary care are global concerns. The Pharmacist and Data driven Quality Improvement in Primary care (P-DQIP) intervention aims to improve prescribing safety via an informatics tool which facilita... Read More about Pharmacist and data-driven quality improvement in primary care (P-DQIP): a qualitative study of anticipated implementation factors informed by the theoretical domains framework..

Qualitative exploration of the acceptability of a postnatal pelvic floor muscle training intervention to prevent urinary incontinence. (2020)
Journal Article
GRANT, A. and CURRIE, S. 2020. Qualitative exploration of the acceptability of a postnatal pelvic floor muscle training intervention to prevent urinary incontinence. BMC women's health [online], 20, article ID 9. Available from: https://doi.org/10.1186/s12905-019-0878-z

Background: Childbirth is a major risk factor for urinary incontinence (UI). As a result, pelvic floor muscle training (PFMT) is commonly recommended during and after pregnancy to prevent the onset of UI. PFMT is often classed as a physical activity... Read More about Qualitative exploration of the acceptability of a postnatal pelvic floor muscle training intervention to prevent urinary incontinence..

Using the theoretical domains framework to explore primary health care practitioner’s perspectives and experiences of preconception physical activity guidance and promotion. (2019)
Journal Article
SISSONS, A., GRANT, A., KIRKLAND, A. and CURRIE, S. 2020. Using the theoretical domains framework to explore primary health care practitioner’s perspectives and experiences of preconception physical activity guidance and promotion. Psychology, health and medicine [online], 24(7), pages 844-854. Available from: https://doi.org/10.1080/13548506.2019.1679846

Preconception physical activity is one of the main predictors of continued engagement in physical activity during and after pregnancy and subsequently, improves the health of women and their child. In the UK, guidance states that Primary Care health... Read More about Using the theoretical domains framework to explore primary health care practitioner’s perspectives and experiences of preconception physical activity guidance and promotion..

Effectiveness and cost-effectiveness of basic versus biofeedback-mediated intensive pelvic floor muscle training for female stress or mixed urinary incontinence: protocol for the OPAL randomised trial. (2019)
Journal Article
HAGEN, S., MCCLURG, D., BUGGE, C., HAY-SMITH, J., DEAN, S.G., ELDERS, A., GLAZENER, C., ABDEL-FATTAH, M., AGUR, W.I., BOOTH, J., GUERRERO, K., NORRIE, J., KILONZO, M., MCPHERSON, G., MCDONALD, A., STRATTON, S., SERGENSON, N., GRANT, A. and WILSON, L. 2019. Effectiveness and cost-effectiveness of basic versus biofeedback-mediated intensive pelvic floor muscle training for female stress or mixed urinary incontinence: protocol for the OPAL randomised trial. BMJ open [online], 9(2), article ID e024153. Available from: https://doi.org/10.1136/bmjopen-2018-024153

Introduction: Accidental urine leakage is a distressing problem that affects around one in three women. The main types of urinary incontinence (UI) are stress, urgency and mixed, with stress being most common. Current UK guidelines recommend that wom... Read More about Effectiveness and cost-effectiveness of basic versus biofeedback-mediated intensive pelvic floor muscle training for female stress or mixed urinary incontinence: protocol for the OPAL randomised trial..

Effectiveness and cost-effectiveness randomised controlled trial of basic versus biofeedback-mediated intensive pelvic floor muscle training for female stress or mixed urinary incontinence: protocol for the OPAL (optimising pelvic floor exercises to achieve long-term benefits) trial mixed methods longitudinal qualitative case study and process evaluation. (2019)
Journal Article
GRANT, A., DEAN, S., HAY-SMITH, J., HAGEN, S., MCCLURG, D., TAYLOR, A., KOVANDZIC, M. and BUGGE, C. 2019. Effectiveness and cost-effectiveness randomised controlled trial of basic versus biofeedback-mediated intensive pelvic floor muscle training for female stress or mixed urinary incontinence: protocol for the OPAL (optimising pelvic floor exercises to achieve long-term benefits) trial mixed methods longitudinal qualitative case study and process evaluation. BMJ open [online], 9(2), article ID e024152. Available from: https://doi.org/10.1136/bmjopen-2018-024152

Introduction: Female urinary incontinence (UI) is common affecting up to 45% of women. Pelvic floor muscle training (PFMT) is the first-line treatment but there is uncertainty whether intensive PFMT is better than basic PFMT for long-term symptomatic... Read More about Effectiveness and cost-effectiveness randomised controlled trial of basic versus biofeedback-mediated intensive pelvic floor muscle training for female stress or mixed urinary incontinence: protocol for the OPAL (optimising pelvic floor exercises to achieve long-term benefits) trial mixed methods longitudinal qualitative case study and process evaluation..

Process evaluation of the Data-driven Quality Improvement in Primary Care (DQIP) trial: quantitative examination of variation between practices in recruitment, implementation and effectiveness. (2018)
Journal Article
DREISCHULTE, T., GRANT, A., HAPCA, A. and GUTHRIE, B. 2018. Process evaluation of the Data-driven Quality Improvement in Primary Care (DQIP) trial: quantitative examination of variation between practices in recruitment, implementation and effectiveness. BMJ open [online], 8(1), article ID e017133. Available from: https://doi.org/10.1136/bmjopen-2017-017133

The cluster randomised trial of the Data-driven Quality Improvement in Primary Care (DQIP) intervention showed that education, informatics and financial incentives for general medical practices to review patients with ongoing high-risk prescribing of... Read More about Process evaluation of the Data-driven Quality Improvement in Primary Care (DQIP) trial: quantitative examination of variation between practices in recruitment, implementation and effectiveness..

Process evaluation of the data-driven quality improvement in primary care (DQIP) trial: case study evaluation of adoption and maintenance of a complex intervention to reduce high-risk primary care prescribing. (2017)
Journal Article
GRANT, A., DREISCHULTE, T. and GUTHRIE, B. 2017. Process evaluation of the data-driven quality improvement in primary care (DQIP) trial: case study evaluation of adoption and maintenance of a complex intervention to reduce high-risk primary care prescribing. BMJ open [online], 7(3), article number e015281. Available from: https://doi.org/10.1136/bmjopen-2016-015281

Objective: - To explore how different practices responded to the Data-driven Quality Improvement in Primary Care (DQIP) intervention in terms of their adoption of the work, reorganisation to deliver the intended change in care to patients, and whethe... Read More about Process evaluation of the data-driven quality improvement in primary care (DQIP) trial: case study evaluation of adoption and maintenance of a complex intervention to reduce high-risk primary care prescribing..

Process evaluation of the data-driven quality improvement in primary care (DQIP) trial: active and less active ingredients of a multi-component complex intervention to reduce high-risk primary care prescribing. (2017)
Journal Article
GRANT, A., DREISCHULTE, T. and GUTHRIE, B. 2017. Process evaluation of the data-driven quality improvement in primary care (DQIP) trial: active and less active ingredients of a multi-component complex intervention to reduce high-risk primary care prescribing. Implementation science [online], 12, article number 4. Available from https://doi.org/10.1186/s13012-016-0531-2

Background: - Two to 4% of emergency hospital admissions are caused by preventable adverse drug events. The estimated costs of such avoidable admissions in England were {pound}530 million in 2015. The data-driven quality improvement in primary care (... Read More about Process evaluation of the data-driven quality improvement in primary care (DQIP) trial: active and less active ingredients of a multi-component complex intervention to reduce high-risk primary care prescribing..

Why is so much clinical research ignored and what can we do about it? (2016)
Journal Article
GRANT, A., TREWEEK, S. and WELLS, M. 2016. Why is so much clinical research ignored and what can we do about it? British journal of hospital medicine [online], 77(Supp. 10), pages 554-555. Available from: https://doi.org/10.12968/hmed.2016.77.10.554

The key points of this article are 1) Research evidence from clinical trials is not being translated into clinical practice in a timely manner and this represents an enormous waste of resources and missed opportunities. 2) Trials do not publish infor... Read More about Why is so much clinical research ignored and what can we do about it?.

Safer prescribing: a trial of education, informatics, and financial incentives. (2016)
Journal Article
DREISCHULTE, T., DONNAN, P., GRANT, A., HAPCA, A., MCCOWAN, C. and GUTHRIE, B. 2016. Safer prescribing: a trial of education, informatics, and financial incentives. New England journal of medicine [online], 374(11), pages 1053-1064. Available from: https://doi.org/10.1056/NEJMsa1508955

High-risk prescribing and preventable, drug-related complications are common in primary care. We evaluated whether the rates of high-risk prescribing by primary care clinicians and the related clinical outcomes would be reduced through a complex inte... Read More about Safer prescribing: a trial of education, informatics, and financial incentives..

Developing a complex intervention to improve prescribing safety in primary care: mixed methods feasibility and optimisation pilot study. (2014)
Journal Article
GRANT, A.M., GUTHRIE, B. and DREISCHULTE, T. 2014. Developing a complex intervention to improve prescribing safety in primary care: mixed methods feasibility and optimisation pilot study. BMJ open [online], 4(1), article number 004153. Available from: https://doi.org/10.1136/bmjopen-2013-004153

Objectives: (A) To measure the extent to which different candidate outcome measures identified highrisk prescribing that is potentially changeable by the data-driven quality improvement in primary care (DQIP) intervention.(B) To explore the value of... Read More about Developing a complex intervention to improve prescribing safety in primary care: mixed methods feasibility and optimisation pilot study..

Pro's and con's of the stepped wedge design in cluster randomised trials of quality improvement interventions: two current examples. (2013)
Journal Article
DREISCHULTE, T., GRANT, A., DONNAN, P. and GUTHRIE, B. 2013. Pro's and con's of the stepped wedge design in cluster randomised trials of quality improvement interventions: two current examples. Trials [online], 14(Supplement 1): oral and poster presentations of the 2nd Clinical trials methodology conference 2013: methodology matters, 18-19 November 2013, Edinburgh, UK, abstract O87. Available from: https://doi.org/10.1186/1745-6215-14-S1-O87

The stepped wedge design, under which all trial participants receive the intervention but the order in which the intervention is received is randomised, is potentially useful to rigorously evaluate organisational interventions to improve quality and... Read More about Pro's and con's of the stepped wedge design in cluster randomised trials of quality improvement interventions: two current examples..

Parallel process evaluation using a proposed framework for the design and reporting of process evaluations for cluster-randomised trials of complex interventions. (2013)
Journal Article
GRANT, A., DREISCHULTE, T. and GUTHRIE, B. 2013. Parallel process evaluation using a proposed framework for the design and reporting of process evaluations for cluster-randomised trials of complex interventions. Trials [online], 14(Supplement 1): oral and poster presentations from the 2nd Clinical trials methodology conference 2013: methodology matters, 18-19 November 2013, Edinburgh, UK, Article O88. Available from: https://doi.org/10.1186/1745-6215-14-S1-O88

Process evaluations are recommended to open the 'black box' of complex interventions evaluated in trials, but there is limited guidance to help with design, with most guidance focused on the use of qualitative methods rather than processes to evaluat... Read More about Parallel process evaluation using a proposed framework for the design and reporting of process evaluations for cluster-randomised trials of complex interventions..

Acceptability and perceived barriers and facilitators to creating a national research register to enable 'direct to patient' enrolment into research: the Scottish Health Research Register (SHARE). (2013)
Journal Article
GRANT, A., URE, J., NICOLSON, D.J., HANLEY, J., SHEIKH, A., MCKINSTRY, B. and SULLIVAN, F. 2013. Acceptability and perceived barriers and facilitators to creating a national research register to enable 'direct to patient' enrolment into research: the Scottish Health Research Register (SHARE). BMC health services research [online], 13, article number 422. Available from: https://doi.org/10.1186/1472-6963-13-422

Background: Difficulties with recruitment pose a major, increasingly recognised challenge to the viability of research. We sought to explore whether a register of volunteers interested in research participation, with data linkage to electronic health... Read More about Acceptability and perceived barriers and facilitators to creating a national research register to enable 'direct to patient' enrolment into research: the Scottish Health Research Register (SHARE)..

An ethnographic exploration of influences on prescribing in general practice: why is there variation in prescribing practices? (2013)
Journal Article
GRANT, A., SULLIVAN, F. and DOWELL, J. 2013. An ethnographic exploration of influences on prescribing in general practice: why is there variation in prescribing practices? Implementation science [online], 8, article 72. Available from: https://doi.org/10.1186/1748-5908-8-72

Prescribing is a core activity for general practitioners, yet significant variation in the quality of prescribing has been reported. This suggests there may be room for improvement in the application of the current best research evidence. There has b... Read More about An ethnographic exploration of influences on prescribing in general practice: why is there variation in prescribing practices?.