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Weights, resistance bands, and rest days are best for tendinopathy. [NIHR Alert] (2024)
Journal Article
SAUL, H., CASSIDY, S., SWAITHES, L. and PAVLOVA, A. 2024. Weights, resistance bands and rest days are best for tendinopathy. [NIHR Alert]. BMJ [online], 384, article q513. Available from: https://doi.org/10.1136/bmj.q513

This NIHR alert is a plain English summary of an original research article, PAVLOVA, A.V., SHIM, J.S.C., MOSS, R., MACLEAN, C., BRANDIE, D., MITCHELL, L., GREIG, L., PARKINSON, E., ALEXANDER, L., BROWN, V.T., MORRISSEY, D., COOPER, K. and SWINTON, P.... Read More about Weights, resistance bands, and rest days are best for tendinopathy. [NIHR Alert].

Exercise therapy for tendinopathy: a mixed-methods evidence synthesis exploring feasibility, acceptability and effectiveness. (2023)
Journal Article
COOPER, K., ALEXANDER, L., BRANDIEC, D., TZORTZIOU BROWN, V., GREIG, L., HARRISON, I., MACLEAN, C., MITCHELL, L., MORRISSEY, D., MOSS, R.A., PARKINSON, E., PAVLOVA, A.V., SHIM, J. and SWINTON, P.A. 2023. Exercise therapy for tendinopathy: a mixed-methods evidence synthesis exploring feasibility, acceptability and effectiveness. Health technology assessment [online], 27(24). Available from: https://doi.org/10.3310/TFWS2748

Tendons are cords of strong, flexible tissue that attach muscles to bones, allowing joints to move. Tendinopathy is a common condition that can affect any tendon in the body, causing pain and limiting function. Exercise is often used to treat tendino... Read More about Exercise therapy for tendinopathy: a mixed-methods evidence synthesis exploring feasibility, acceptability and effectiveness..

Manual patient handling in the healthcare setting: a scoping review. (2023)
Journal Article
JOHNSON, K., SWINTON, P., PAVLOVA, A. and COOPER, K. 2023. Manual patient handling in the healthcare setting: a scoping review. Physiotherapy [online], 120, pages 60-77. Available from: https://doi.org/10.1016/j.physio.2023.06.003

Manual patient handling is the most frequently reported risk factor for work-related musculoskeletal disorders in healthcare. Patient handling tasks are routinely performed manually without assistive devices, and can create awkward postures and high... Read More about Manual patient handling in the healthcare setting: a scoping review..

Patient ratings in exercise therapy for the management of tendinopathy: a systematic review with meta-analysis. (2023)
Journal Article
SHIM, J., PAVLOVA, A.V., MOSS, R.A., MACLEAN, C., BRANDIE, D., MITCHELL, L., GREIG, L., PARKINSON, E., TZORTZIOU BROWN, V., MORRISSEY, D., ALEXANDER, L., COOPER, K. and SWINTON, P.A. 2023. Patient ratings in exercise therapy for the management of tendinopathy: a systematic review with meta-analysis. Physiotherapy [online], 120, pages 78-94. Available from: https://doi.org/10.1016/j.physio.2023.05.002

The objective of this study was to synthesise exercise therapy intervention data investigating patient rating outcomes for the management of tendinopathy. A systematic review and meta-analysis of randomised controlled trials investigating exercise th... Read More about Patient ratings in exercise therapy for the management of tendinopathy: a systematic review with meta-analysis..

Effect of resistance exercise dose components for tendinopathy management: a systematic review with meta-analysis. (2023)
Journal Article
PAVLOVA, A.V., SHIM, J.S.C., MOSS, R., MACLEAN, C., BRANDIE, D., MITCHELL, L., GREIG, L., PARKINSON, E., ALEXANDER, L., BROWN, V.T., MORRISSEY, D., COOPER, K. and SWINTON, P.A. 2023. Effect of resistance exercise dose components for tendinopathy management: a systematic review with meta-analysis. British journal of sports medicine [online], 57(20), pages 1327-1334. Available from: https://doi.org/10.1136/bjsports-2022-105754

The objective of this study was to investigate potential moderating effects of resistance exercise dose components - including intensity, volume and frequency - for the management of common tendinopathies. The study was conducted through a systematic... Read More about Effect of resistance exercise dose components for tendinopathy management: a systematic review with meta-analysis..

What are small, medium and large effect sizes for exercise treatments of tendinopathy? A systematic review and meta-analysis. (2023)
Journal Article
SWINTON, P.A., SHIM, J.S.C., PAVLOVA, A.V., MOSS, R., MACLEAN, C., BRANDIE, D., MITCHELL, L., GREIG, L., PARKINSON, E., BROWN, V.T., MORRISSEY, D., ALEXANDER, L. and COOPER, K. 2023. What are small, medium and large effect sizes for exercise treatments of tendinopathy? A systematic review and meta-analysis. BMJ open sport and exercise medicine [online], 9(1), article number e001389. Available from: https://doi.org/10.1136/bmjsem-2022-001389

The objective of this study was to quantify and describe effect size distributions from exercise therapies across a range of tendinopathies and outcome domains, to inform future research and clinical practice through conducting a systematic review wi... Read More about What are small, medium and large effect sizes for exercise treatments of tendinopathy? A systematic review and meta-analysis..

Health technologies for the prevention and detection of falls in adult hospital inpatients: a scoping review. (2021)
Journal Article
COOPER, K., PAVLOVA, A., GREIG, L., SWINTON, P., KIRKPATRICK, P., MITCHELHILL, F., SIMPSON, S., STEPHEN, A. and ALEXANDER, L. 2021. Health technologies for the prevention and detection of falls in adult hospital inpatients: a scoping review. JBI evidence synthesis [online], 19(10), pages 2478-2658. Available from: https://doi.org/10.11124/JBIES-20-00114

Objective:The objective of this scoping review was to examine and map the evidence relating to the reporting and evaluation of technologies for the prevention and detection of falls in adult hospital inpatients.Introduction:Falls are a common cause o... Read More about Health technologies for the prevention and detection of falls in adult hospital inpatients: a scoping review..

Is intrinsic lumbar spine shape associated with lumbar disc degeneration? An exploratory study. (2020)
Journal Article
DEANE, J.A., PAVLOVA, A.V., LIM, A.K.P., GREGORY, J.S., ASPDEN, R.M. and MCGREGOR, A.H. 2020. Is intrinsic lumbar spine shape associated with lumbar disc degeneration? An exploratory study. BMC musculoskeletal disorders [online], 21, article number 433. Available from: https://doi.org/10.1186/s12891-020-03346-7

Background: Lumbar disc degeneration (LDD) is a condition associated with recurrent low back pain (LBP). Knowledge regarding effective management is limited. As a step towards the identification of risk, prognostic or potentially modifiable factors i... Read More about Is intrinsic lumbar spine shape associated with lumbar disc degeneration? An exploratory study..

Motor development in infancy and spine shape in early old age: findings from a British birth cohort study. (2020)
Journal Article
SAUNDERS, F.R., GREGORY, J.S., PAVLOVA, A.V., MUTHURI, S.G., HARDY, R.J., MARTIN, K.R., BARR, R.J., ADAMS, J.E., KUH, D., ASPDEN, R.M., COOPER, R. and IRELAND, A. 2020. Motor development in infancy and spine shape in early old age: findings from a British birth cohort study. Journal of orthopaedic research [online], 38(12), pages 2740-2748. Available from: https://doi.org/10.1002/jor.24656

Spine shape changes dramatically in early life, influenced by attainment of developmental milestones such as independent walking. Whether these associations persist across life is unknown. Therefore, we investigated associations between developmental... Read More about Motor development in infancy and spine shape in early old age: findings from a British birth cohort study..

Perinatal factors associate with vertebral size and shape but not lumbar lordosis in 10-year-old children. (2019)
Journal Article
PAVLOVA, A.V., JEFFREY, J.E., BARR, R.J. and ASPDEN, R.M. 2019. Perinatal factors associate with vertebral size and shape but not lumbar lordosis in 10-year-old children. Journal of anatomy [online], 235(4), pages 749-756. Available from: https://doi.org/10.1111/joa.13024

The intrauterine environment is known to influence foetal development and future health. Low birthweight has been linked to smaller vertebral canals in children and decreased adulthood spine bone mineral content. Perinatal factors affecting lumbar sp... Read More about Perinatal factors associate with vertebral size and shape but not lumbar lordosis in 10-year-old children..

Age at onset of walking in infancy is associated with hip shape in early old age. (2019)
Journal Article
IRELAND, A., SAUNDERS, F.R., MUTHURI, S.G., PAVLOVA, A.V., HARDY, R.J., MARTIN, K.R., BARR, R.J., ADAMS, J.E., KUH, D., ASPDEN, R.M. GREGORY, J.S. and COOPER, R. 2019. Age at onset of walking in infancy is associated with hip shape in early old age. Journal of bone and mineral research [online], 34(3), pages 455-463. Available from: https://doi.org/10.1002/jbmr.3627

Bones' shapes and structures adapt to the muscle and reaction forces they experience during everyday movements. Onset of independent walking, at approximately 12 months, represents the first postnatal exposure of the lower limbs to the large forces a... Read More about Age at onset of walking in infancy is associated with hip shape in early old age..

Associations between back pain across adulthood and spine shape in early old age in a British birth cohort. (2018)
Journal Article
MUTHURI, S.G., PAVLOVA, A.V., SAUNDERS, F.R., HARDY, R.J., GREGORY, J.S., BARR, R.J., MARTIN, K.R., ADAMS, J.E., KUH, D., ASPDEN, R.M. and COOPER, R. 2018. Associations between back pain across adulthood and spine shape in early old age in a British birth cohort. Scientific reports [online], 8, article ID 16309. Available from: https://doi.org/10.1038/s41598-018-34628-9

We aimed to examine whether back pain across adulthood was associated with spine shape at age 60–64 years. Data were from 1405 participants in the MRC National Survey of Health and Development, a nationally representative British birth cohort. Back p... Read More about Associations between back pain across adulthood and spine shape in early old age in a British birth cohort..

Variation in lifting kinematics related to individual intrinsic lumbar curvature: an investigation in healthy adults. (2018)
Journal Article
PAVLOVA, A.V., MEAKIN, J.R., COOPER, K., BARR, R.J. and ASPDEN, R.M. 2018. Variation in lifting kinematics related to individual intrinsic lumbar curvature: an investigation in healthy adults. BMJ open sport and exercise medicine [online], 4(1), article number 000374. Available from: https://doi.org/10.1136/bmjsem-2018-000374

Objective: Lifting postures are frequently implicated in back pain. We previously related responses to a static load with intrinsic spine shape, and here we investigate the role of lumbar spine shape in lifting kinematics. Methods: Thirty healthy adu... Read More about Variation in lifting kinematics related to individual intrinsic lumbar curvature: an investigation in healthy adults..

Body mass index and waist circumference in early adulthood are associated with thoracolumbar spine shape at age 60-64: The Medical Research Council National Survey of Health and Development. (2018)
Journal Article
PAVLOVA, A.V., MUTHURI, S.G., COOPER, R., SAUNDERS, F.R., GREGORY, J.S., BARR, R.J., MARTIN, K.R., ADAMS, J.E., KUH, D., HARDY, R.J. and ASPDEN, R.M. 2018. Body mass index and waist circumference in early adulthood are associated with thoracolumbar spine shape at age 60-64: The Medical Research Council National Survey of Health and Development. PLoS ONE [online], 13(6), article ID e0197570. Available from: https://doi.org/10.1371/journal.pone.0197570

This study investigated associations between measures of adiposity from age 36 and spine shape at 60-64 years. Thoracolumbar spine shape was characterised using statistical shape modelling on lateral dual-energy x-ray absorptiometry images of the spi... Read More about Body mass index and waist circumference in early adulthood are associated with thoracolumbar spine shape at age 60-64: The Medical Research Council National Survey of Health and Development..

Associations between body mass index across adult life and hip shapes at age 60 to 64: evidence from the 1946 British birth cohort. (2017)
Journal Article
MUTHURI, S., SAUNDERS, F.R., HARDY, R.J., PAVLOVA, A.V., MARTIN, K.R., GREGORY, J.S., BARR, R.J, ADAMS, J.E., KUH, D., ASPDEN, R.M. and COOPER, R. 2017. Associations between body mass index across adult life and hip shapes at age 60 to 64: evidence from the 1946 British birth cohort. Bone [online], 105, pages 115-121. Available from: https://doi.org/10.1016/j.bone.2017.08.017

Objective: To examine the associations of body mass index (BMI) across adulthood with hip shapes at age 60-64years. Methods: Up to 1633 men and women from the MRC National Survey of Health and Development with repeat measures of BMI across adulthood... Read More about Associations between body mass index across adult life and hip shapes at age 60 to 64: evidence from the 1946 British birth cohort..

Statistical shape modelling of hip and lumbar spine morphology and their relationship in the MRC National Survey of Health and Development. (2017)
Journal Article
PAVLOVA, A.V., SAUNDERS, F.R., MUTHURI, S.G., GREGORY, J.S., BARR, R.J., MARTIN, K.R., HARDY, R.J., COOPER, R., ADAMS, J.E., KUH, D. and ASPDEN, R.M. 2017. Statistical shape modelling of hip and lumbar spine morphology and their relationship in the MRC National Survey of Health and Development. Journal of anatomy [online], 231(2), pages 248-259. Available from: https://doi.org/10.1111/joa.12631

The anatomical shape of bones and joints is important for their proper function, but quantifying this and detecting pathological variations is difficult to do. Numerical descriptions would also enable correlations between joint shapes to be explored.... Read More about Statistical shape modelling of hip and lumbar spine morphology and their relationship in the MRC National Survey of Health and Development..

The lumbar spine has an intrinsic shape specific to each individual that remains a characteristic throughout flexion and extension. (2014)
Journal Article
PAVLOVA, A.V., MEAKIN, J.R., COOPER, K., BARR, R.J. and ASPDEN, R.M. 2014. The lumbar spine has an intrinsic shape specific to each individual that remains a characteristic throughout flexion and extension. European spine journal [online], 23(Suppl 1), pages S26-S32. Available from: https://doi.org/10.1007/s00586-013-3162-1


We have previously shown that the lumbar spine has an intrinsic shape specific to the individual and characteristic of sitting, standing and supine postures. The purpose of this study was to test the hypothesis that this intrinsic shape is detectab... Read More about The lumbar spine has an intrinsic shape specific to each individual that remains a characteristic throughout flexion and extension..