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All Outputs (21)

What is the impact of long-term COVID-19 on workers in healthcare settings? A rapid systematic review of current evidence. (2024)
Journal Article
CRUICKSHANK, M., BRAZZELLI, M., MANSON, P., TORRANCE, N. and GRANT, A. 2024. What is the impact of long-term COVID-19 on workers in healthcare settings? A rapid systematic review of current evidence. PLoS one [online], 19(3), article number e0299743. Available from: https://doi.org/10.1371/journal.pone.0299743

Long COVID is a devastating, long-term, debilitating illness which disproportionately affects healthcare workers, due to the nature of their work. There is currently limited evidence specific to healthcare workers about the experience of living with... Read More about What is the impact of long-term COVID-19 on workers in healthcare settings? A rapid systematic review of current evidence..

Unforeseen emotional labour: a collaborative autoethnography exploring researcher experiences of studying long COVID in health workers during the COVID-19 pandemic. (2023)
Journal Article
MACIVER, E., ADAMS, N.N., TORRANCE, N., DOUGLAS, F., KENNEDY, C., SKATUN, D., SANTIAGO, V.H. and GRANT, A. 2024. Unforeseen emotional labour: a collaborative autoethnography exploring researcher experiences of studying long COVID in health workers during the COVID-19 pandemic. SSM - qualitative research in health [online], 5, article 100390. Available from: https://doi.org/10.1016/j.ssmqr.2023.100390

The concept of "emotional labour" describes the regulation of feelings and expressions to fulfil a specific job role, discussed extensively in relation to commercial and caring professions, with more recent scholarship recognising the emotional role... Read More about Unforeseen emotional labour: a collaborative autoethnography exploring researcher experiences of studying long COVID in health workers during the COVID-19 pandemic..

Lived experience of work and long COVID in healthcare staff. (2023)
Journal Article
TORRANCE, N., MACIVER, E., ADAMS, N.N., SKÅTUN, D., SCOTT, N., KENNEDY, C., DOUGLAS, F., HERNANDEZ-SANTIAGO, V. and GRANT, A. 2024. Lived experience of work and long COVID in healthcare staff. Occupational medicine [online], 74(1), pages 78-85. Available from: https://doi.org/10.1093/occmed/kqad117

Healthcare workers (HCWs) had a greater occupational risk of exposure to coronavirus disease 2019 (COVID-19) and reported higher rates of long COVID (LC). This has implications for the provision of health care in already stretched health services. Th... Read More about Lived experience of work and long COVID in healthcare staff..

Is age discrimination a risk factor for frailty progression and frailty development among older adults? A prospective cohort analysis of the English Longitudinal Study of Ageing. (2023)
Journal Article
AMINU, A.Q., TORRANCE, N., GRANT, A. and KYDD, A. 2024. Is age discrimination a risk factor for frailty progression and frailty development among older adults? A prospective cohort analysis of the English Longitudinal Study of Ageing. Archives of gerontology and geriatrics [online], 118, article number 105282. Available from: https://doi.org/10.1016/j.archger.2023.105282

With the increasing global burden of frailty on healthcare resources, it is important to understand the modifiable risk factors of frailty. This study examined perceived age discrimination as a potential risk factor for frailty progression and frailt... Read More about Is age discrimination a risk factor for frailty progression and frailty development among older adults? A prospective cohort analysis of the English Longitudinal Study of Ageing..

Assessing the impact of a national clinical guideline for the management of chronic pain on opioid prescribing rates: a controlled interrupted time series analysis. (2022)
Journal Article
HÉBERT, H.L., MORALES, D.R., TORRANCE, N.A., SMITH, B.H. and COLVIN, L.A. 2022. Assessing the impact of a national clinical guideline for the management of chronic pain on opioid prescribing rates: a controlled interrupted time series analysis. Implementation science [online], 17(1), article number 77. Available from: https://doi.org/10.1186/s13012-022-01251-2

Background: Opioids can be effective analgesics, but long-term use may be associated with harms. In 2013, the first national, comprehensive, evidence-based pain management guideline was published, from the Scottish Intercollegiate Guideline Network (... Read More about Assessing the impact of a national clinical guideline for the management of chronic pain on opioid prescribing rates: a controlled interrupted time series analysis..

Abdominal cancer symptoms: evaluation of the impact of a regional public awareness campaign. (2021)
Journal Article
TORRANCE, N., BRIGHT, C.J., HILL, H.L., FERGUSSON, J., KENNEDY, C., MAK, V., GILDEA, C., NORDIN, A. and ELLISS-BROOKES, L. 2021. Abdominal cancer symptoms: evaluation of the impact of a regional public awareness campaign. European journal of cancer care [online], 30(6), e13500. Available from: https://doi.org/10.1111/ecc.13500

Objective: A regional ‘Be Clear on Cancer’ (BCoC) campaign developed by Public Health England aimed to promote public awareness of key abdominal cancer symptoms in people aged 50 years and over. Methods: Data were analysed for metrics at different st... Read More about Abdominal cancer symptoms: evaluation of the impact of a regional public awareness campaign..

Trends in gabapentinoid prescribing, co-prescribing of opioids and benzodiazepines, and associated deaths in Scotland. (2020)
Journal Article
TORRANCE, N., VELUCHAMY, A., ZHOU, Y., FLETCHER, E., MOIR, E., HEBERT, H., DONNAN, P., WATSON, J., COLVIN, L. and SMITH, B. 2020. Trends in gabapentinoid prescribing, co-prescribing of opioids and benzodiazepines, and associated deaths in Scotland. British journal of anaesthesia [online], 125(2), pages 159-167. Available from: https://doi.org/10.1016/j.bja.2020.05.017

Background: Gabapentinoid drugs (gabapentin and pregabalin) are effective in neuropathic pain, which has a prevalence of ~7%. Concerns about increased prescribing have implications for patient safety, misuse, and diversion. Drug-related deaths (DRDs)... Read More about Trends in gabapentinoid prescribing, co-prescribing of opioids and benzodiazepines, and associated deaths in Scotland..

Association of opioid prescribing practices with chronic pain and benzodiazepine co-prescription: a primary care data linkage study. (2018)
Journal Article
TORRANCE, N., MANSOOR, R., WANG, H., GILBERT, S., MACFARLANE, G.J., SERPELL, M., BALDACCHINO, A., HALES, T.G., DONNAN, P., WYPER, G., SMITH, B.H. and COLVIN, L. 2018. Association of opioid prescribing practices with chronic pain and benzodiazepine co-prescription: a primary care data linkage study. British journal of anaesthesia [online], 120(6), pages 1345-1355. Available from : https://doi.org/10.1016/j.bja.2018.02.022

Background: Opioid prescribing is increasing worldwide with associated increases in misuse and other harms. We studied variations in national opioid prescription rates, indicators of prescribing quality, co-prescribing of benzodiazepines and relation... Read More about Association of opioid prescribing practices with chronic pain and benzodiazepine co-prescription: a primary care data linkage study..

Chronic pain, depression and cardiovascular disease linked through a shared genetic predisposition: analysis of a family-based cohort and twin study. (2017)
Journal Article
VAN HECKE, O., HOCKING, L.J., TORRANCE, N., CAMPBELL, A., PADMANABHAN, S., PORTEOUS, D.J., MCINTOSH, A.M., BURRI, A.V., TANAKA, H., WILLIAMS, F.M.K. and SMITH, B.H. 2017. Chronic pain, depression and cardiovascular disease linked through a shared genetic predisposition: analysis of a family-based cohort and twin study. PLoS ONE [online], 12(2), article ID e0170653. Available from: https://doi.org/10.1371/journal.pone.0170653

Depression and chronic pain are the two most important causes of disability. They occur together more frequently than expected and both conditions have been shown to be co-morbid with cardiovascular disease. Although shared socio-demographic risk fac... Read More about Chronic pain, depression and cardiovascular disease linked through a shared genetic predisposition: analysis of a family-based cohort and twin study..

Risk factors for neuropathic pain in diabetes mellitus. (2016)
Journal Article
HÉBERT, H.L., VELUCHAMY, A., TORRANCE, N. and SMITH, B.L. 2017. Risk factors for neuropathic pain in diabetes mellitus. Pain [online], 158(4), pages 560-568. Available from: http://dx.doi.org/10.1097/j.pain.0000000000000785

According to the International Diabetes Federation, diabetes mellitus (DM) is estimated to affect around 415 million adults worldwide, roughly 8.8% of the adult population, with the figure projected to rise to over 600 million by 2040. Regional preva... Read More about Risk factors for neuropathic pain in diabetes mellitus..

Identification and management of chronic pain in primary care: a review. (2016)
Journal Article
MILLS, S., TORRANCE, N. and SMITH, B.H. 2016. Identification and management of chronic pain in primary care: a review. Current psychiatry reports [online], 18(2), article ID 22. Available from: https://doi.org/10.1007/s11920-015-0659-9

Chronic pain is a common, complex, and challenging condition, where understanding the biological, social, physical and psychological contexts is vital to successful outcomes in primary care. In managing chronic pain the focus is often on promoting re... Read More about Identification and management of chronic pain in primary care: a review..

An epidemiological study of neuropathic pain symptoms in Canadian adults. (2015)
Journal Article
VANDENKERKHOF, E.G., MANN, E.G., TORRANCE, N., SMITH, B.H., JOHNSON, A. and GILRON, I. 2016. An epidemiological study of neuropathic pain symptoms in Canadian adults. Pain research and management [online], 2016, article ID 9815750. Available from: https://doi.org/10.1155/2016/9815750

The reported prevalence of neuropathic pain ranges from 6.9% to 10%; however the only Canadian study reported 17.9%. The objective of this study was to describe the epidemiology of neuropathic pain in Canada. A cross-sectional survey was conducted in... Read More about An epidemiological study of neuropathic pain symptoms in Canadian adults..

A genome-wide association study provides evidence of sex-specific involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) with diabetic neuropathic pain. (2015)
Journal Article
MENG, W., DESHMUKH, H.A., DONNELLY, L.A., WELLCOME TRUST CASE CONTROL CONSORTIUM 2 (WTCCC2), SURROGATE MARKERS FOR MICRO- AND MACRO-VASCULAR HARD ENDPOINTS FOR INNOVATIVE DIABETES TOOLS (SUMMIT) STUDY GROUP, TORRANCE, N., COLHOUN, H.M., PALMER, C.N.A. and SMITH, B.H. 2015. A genome-wide association study provides evidence of sex-specific involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) with diabetic neuropathic pain. EBioMedicine [online], 2(10), pages 1386-1393. Available from: https://doi.org/10.1016/j.ebiom.2015.08.001

Neuropathic pain is defined as pain arising as a direct consequence of a lesion or a disease affecting the somatosensory system and it affects around 1 in 4 diabetic patients in the UK. The purpose of this genome-wide association study (GWAS) was to... Read More about A genome-wide association study provides evidence of sex-specific involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) with diabetic neuropathic pain..

Estimating the burden of disease in chronic pain with and without neuropathic characteristics: does the choice between the EQ-5D and SF-6D matter? (2014)
Journal Article
TORRANCE, N., LAWSON, K.D., AFOLABI, E., BENNETT, M.I., SERPELL, M.G., DUNN, K.M. and SMITH, B.H. 2014. Estimating the burden of disease in chronic pain with and without neuropathic characteristics: does the choice between the EQ-5D and SF-6D matter? Pain [online], 155(10), pages 1996-2004. Available from: https://doi.org/10.1016/j.pain.2014.07.001

Chronic pain with neuropathic characteristics is associated with significantly lower EQ-5D and Short Form 6D health utilities scores, with 17% reporting health states 'worse than death'. The EQ-5D and Short Form (SF)12 are widely used generic health-... Read More about Estimating the burden of disease in chronic pain with and without neuropathic characteristics: does the choice between the EQ-5D and SF-6D matter?.

Corrigendum to 'Neuropathic pain in the general population: a systematic review of epidemiological studies' (2014)
Journal Article
VAN HECKE, O., AUSTIN, S.K., KHAN, R.A., SMITH, B.H. and TORRANCE, N. 2014. Corrigendum to 'Neuropathic pain in the general population: a systematic review of epidemiological studies'. Pain [online], 155(9), page 1907. Available from: https://doi.org/10.1016/j.pain.2014.06.006

In the original article the data in Table 2 was unclear. This corrigendum is a revised version of this data.

Does a history of depression actually mediate smoking-related pain? Findings from a cross-sectional general population-based study. (2014)
Journal Article
VAN HECKE, O., TORRANCE, N., COCHRANE, L., CAVANAGH, J., DONNAN, P.T., PADMANABHAN, S., PORTEOUS, D.J., HOCKING, L. and SMITH, B.H. 2014. Does a history of depression actually mediate smoking-related pain? Findings from a cross-sectional general population-based study. European journal of pain [online], 18(9), pages 1223-1230. Available from: https://doi.org/10.1002/j.1532-2149.2014.00470.x

Background: Smokers report more pain and worse functioning. The evidence from pain clinics suggests that depression affects this relationship: The association between smoking and chronic pain is weakened when controlling for depression. This study ex... Read More about Does a history of depression actually mediate smoking-related pain? Findings from a cross-sectional general population-based study..

What do we mean by 'older adults' persistent pain self-management'? A concept analysis. (2014)
Journal Article
STEWART, C., SCHOFIELD, P., ELLIOTT, A.M., TORRANCE, N. and LEVEILLE, S. 2014. What do we mean by 'older adults' persistent pain self-management'? A concept analysis. Pain medicine [online], 15(2), pages 214-224. Available from: https://doi.org/10.1111/pme.12251

Background: No standard definition exists for the concept “persistent pain self-management” or how it should be defined in relation to older adults. Poorly defined concepts can result in misunderstandings in the clinical setting and can hinder resear... Read More about What do we mean by 'older adults' persistent pain self-management'? A concept analysis..

Neuropathic pain in the general population: a systematic review of epidemiological studies. (2013)
Journal Article
VAN HECKE, O., AUSTIN, S.K., KHAN, R.A., SMITH, B.H. and TORRANCE, N. 2014. Neuropathic pain in the general population: a systematic review of epidemiological studies. Pain [online], 155(4), pages 654-662. Available from: https://doi.org/10.1016/j.pain.2013.11.013

Most patients with neuropathic pain symptoms present and are managed in primary care, with only a minority being referred for specialist clinical assessment and diagnoses. Previous reviews have focused mainly on specific neuropathic pain conditions b... Read More about Neuropathic pain in the general population: a systematic review of epidemiological studies..

Is there evidence for aetiologically distinct subgroups of idiopathic congenital talipes equinovarus? A case-only study and pedigree analysis. (2011)
Journal Article
CARDY, A.H., SHARP, L., TORRANCE, N., HENNEKAM, R.C. and MIEDZYBRODZKA, Z. 2011. Is there evidence for aetiologically distinct subgroups of idiopathic congenital talipes equinovarus? A case-only study and pedigree analysis. PLOS one [online], 6(4), article number e17895. Available from: https://doi.org/10.1371/journal.pone.0017895

Idiopathic congenital talipes equinovarus (CTEV) is a common developmental foot disorder, the aetiology of which remains largely unknown. Some aspects of the epidemiology suggest the possibility of aetiologically distinct subgroups. Previous studies... Read More about Is there evidence for aetiologically distinct subgroups of idiopathic congenital talipes equinovarus? A case-only study and pedigree analysis..

Clinical governance and research ethics as barriers to UK low-risk population-based health research? (2008)
Journal Article
VAN TEIJLINGEN, E.R., DOUGLAS, F. and TORRANCE, N. 2008. Clinical governance and research ethics as barriers to UK low-risk population-based health research? BMC public health [online], 8, article 396. Available from: https://doi.org/10.1186/1471-2458-8-396

Background: Since the Helsinki Declaration was introduced in 1964 as a code of practice for clinical research, it has generally been agreed that research governance is also needed in the field of public health and health promotion research. Recently,... Read More about Clinical governance and research ethics as barriers to UK low-risk population-based health research?.