All Outputs (37)

Effects of exercise training response on quality of life and cardiovascular risk factor profiles in people with coronary artery disease: insights from the HIIT or MISS UK trial. (2024)
Journal Article
INGLE, L., POWELL, R., BEGG, B., BIRKETT, S.T., NICHOLS, S., ENNIS, S., BANERJEE, P., SHAVE, R. and MCGREGOR, G. 2024. Effects of exercise training response on quality of life and cardiovascular risk factor profiles in people with coronary artery disease: insights from the HIIT or MISS UK trial. Archives of physical medicine and rehabilitation [online], 105(8), pages 1464-1479. Available from: https://doi.org/10.1016/j.apmr.2024.03.002

The objective of this study was to compare the characteristics of responders and nonresponders to 8 weeks of exercise training, to determine differences in key cardiovascular disease outcomes in people with coronary artery disease (CAD). This was und... Read More about Effects of exercise training response on quality of life and cardiovascular risk factor profiles in people with coronary artery disease: insights from the HIIT or MISS UK trial..

Inter- and intra-observer reliability and agreement of O2Pulse inflection during cardiopulmonary exercise testing: a comparison of subjective and novel objective methodology. (2024)
Journal Article
NICKOLAY, T., MCGREGOR, G., POWELL, R., BEGG, B., BIRKETT, S., NICHOLS, S., ENNIS, S., BANERJEE, P., SHAVE, R., METCALFE, J., HOYE, A. and INGLE, L. 2024. Inter- and intra-observer reliability and agreement of O2Pulse inflection during cardiopulmonary exercise testing: a comparison of subjective and novel objective methodology. PLoS one [online], 19(3), article number e0299486. Available from: https://doi.org/10.1371/journal.pone.0299486

Cardiopulmonary exercise testing (CPET) is the 'gold standard' method for evaluating functional capacity, with oxygen pulse (O2Pulse) inflections serving as a potential indicator of myocardial ischaemia. However, the reliability and agreement of iden... Read More about Inter- and intra-observer reliability and agreement of O2Pulse inflection during cardiopulmonary exercise testing: a comparison of subjective and novel objective methodology..

Living with myocardial ischaemia and no obstructive coronary arteries: a qualitative study. (2024)
Journal Article
HUMPHREYS, H., PADDOCK, D., BROWN, S., BERRY, C., COWIE, A., DAWKES, S. and NICHOLS, S. 2024. Living with myocardial ischaemia and no obstructive coronary arteries: a qualitative study. Open heart [online], 11(1), article number e002569. Available from: https://doi.org/10.1136/openhrt-2023-002569

This study aims to explore the lived experience of people with myocardial ischaemia with no obstructive arteries. Qualitative study using semistructured interviews using telephone interviews with 17 participants living in the UK. 17 people (2 males,... Read More about Living with myocardial ischaemia and no obstructive coronary arteries: a qualitative study..

Provision of dietary education in UK-based cardiac rehabilitation: a cross-sectional survey conducted in conjunction with the British Association for Cardiovascular Prevention and Rehabilitation. (2023)
Journal Article
JAMES, E., BUTLER, T., NICHOLS, S., GOODALL, S. and O'DOHERTY, A.F. 2024. Provision of dietary education in UK-based cardiac rehabilitation: a cross-sectional survey conducted in conjunction with the British Association for Cardiovascular Prevention and Rehabilitation. British journal of nutrition [online], 131(5), pages 880–893. Available from: https://doi.org/10.1017/S0007114523002374

Dietary education is a core component of cardiac rehabilitation (CR). It is unknown how or what dietary education is delivered across the United Kingdom (UK). We aimed to characterise practitioners who deliver dietary education in UK CR and determine... Read More about Provision of dietary education in UK-based cardiac rehabilitation: a cross-sectional survey conducted in conjunction with the British Association for Cardiovascular Prevention and Rehabilitation..

Remote ischaemic conditioning for fatigue after stroke (RICFAST): a pilot randomised controlled trial. (2023)
Journal Article
MOYLE, B., KUDIERSKY, N., TOTTON, N., SASSANI, M., NICHOLS, S., JENKINS, T., REDGRAVE, J., BAIG, S., NAIR, K.P.S., MAJID, A. and ALI, A.N. 2023. Remote ischaemic conditioning for fatigue after stroke (RICFAST): a pilot randomised controlled trial. Journal of stroke and cerebrovascular diseases [online], 32(12), article number 107420. Available from: https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107420

Post stroke fatigue (PSF) affects 50 % of stroke survivors and can be disabling. Remote ischaemic conditioning (RIC) can preserve mitochondrial function, improve tissue perfusion and may mitigate PSF. This pilot randomised controlled trial evaluates... Read More about Remote ischaemic conditioning for fatigue after stroke (RICFAST): a pilot randomised controlled trial..

Cost-effectiveness of high-intensity interval training (HIIT) vs moderate intensity steady-state (MISS) training in UK cardiac rehabilitation. (2023)
Journal Article
ALBUSTAMI, M., HARTFIEL, N., CHARLES, J.M., POWELL, R., BEGG, B., BIRKETT, S.T., NICHOLS, S., ENNIS, S., HEE, S.W., BANERJEE, P., INGLE, L., SHAVE, R., MCGREGOR, G. and EDWARDS, R.T. 2024. Cost-effectiveness of high-intensity interval training (HIIT) vs moderate intensity steady-state (MISS) training in UK cardiac rehabilitation. Archives of physical medicine and rehabilitation [online], 105(4), pages 639-646. Available from: https://doi.org/10.1016/j.apmr.2023.09.005

The objective of this study was to perform a cost-effectiveness analysis of high-intensity interval training (HIIT) compared with moderate intensity steady-state (MISS) training in people with coronary artery disease (CAD) attending cardiac rehabilit... Read More about Cost-effectiveness of high-intensity interval training (HIIT) vs moderate intensity steady-state (MISS) training in UK cardiac rehabilitation..

A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER). (2023)
Journal Article
NGAAGE, D.L., MITCHELL, N., DEAN, A., MITCHELL, A., HINDE, S., AKOWUAH, E., DOHERTY, P., NICHOLS, S., FAIRHURST, C., FLEMMING, K., HEWITT, C., INGLE, L. and WATSON, J. 2023. A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER). Pilot and feasibility studies [online], 9, article number 79. Available from: https://doi.org/10.1186/s40814-023-01304-3

The aim of this study was to determine the acceptability and feasibility of delivering early outpatient review following cardiac surgery and early cardiac rehabilitation (CR), compared to standard practice to establish if a future large-scale trial i... Read More about A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER)..

Research priorities relating to the delivery of cardiovascular prevention and rehabilitation programmes: results of a modified Delphi process. (2023)
Journal Article
MCHALE, S., COWIE, A., BROWN, S., BUTLER, T., CARVER, K., DALAL, H.M., DAWKES, S., DEIGHAN, C., DOHERTY, P., EVANS, J., HINTON, S., JONES, J., MILLS, J., NICHOLS, S. and TAYLOR, R.S. 2023. Research priorities relating to the delivery of cardiovascular prevention and rehabilitation programmes: results of a modified Delphi process. Open heart [online], 10(1), article e002248. Available from: https://doi.org/10.1136/openhrt-2022-002248

The purpose of this British Association for Cardiovascular Prevention and Rehabilitation (BACPR) research priority setting project (PSP) was to identify a top 10 list of priority research questions for cardiovascular prevention and rehabilitation (CV... Read More about Research priorities relating to the delivery of cardiovascular prevention and rehabilitation programmes: results of a modified Delphi process..

Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: further insights from the CARE-CR study. (2023)
Journal Article
JAMES, E., GOODALL, S., NICHOLS, S., WALKER, K., CARROLL, S., O'DOHERTY, A.F. and INGLE, L. 2023. Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: further insights from the CARE-CR study. Frontiers in medicine [online], 10, article number 1094733. Available from: https://doi.org/10.3389/fmed.2023.1094733

Low muscle mass disproportionately affects people with coronary heart disease compared to healthy controls but is under-researched and insufficiently treated. Inflammation, poor nutrition and neural decline might contribute to low muscle mass. This s... Read More about Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: further insights from the CARE-CR study..

High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial. (2023)
Journal Article
MCGREGOR, G., POWELL, R., BEGG, B. et al. 2023. High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial. European journal of preventive cardiology [online], 30(9), pages 745-755. Available from: https://doi.org/10.1093/eurjpc/zwad039

There is a lack of international consensus regarding the prescription of high-intensity interval training (HIIT) for people with coronary artery disease (CAD) attending cardiac rehabilitation (CR). The aim of this study was therefore to assess the cl... Read More about High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial..

The effectiveness of the Healthworks Staying Steady community-based falls prevention exercise programme to improve physical function in older adults: a 6-year service evaluation. (2022)
Journal Article
JAMES, E., OMAN, P., ALI, M., COURT, P., GOODALL, S., NICHOLS, S.J. and O'DOHERTY, A.F. 2022. The effectiveness of the Healthworks Staying Steady community-based falls prevention exercise programme to improve physical function in older adults: a 6-year service evaluation. BMC public health [online], 22, article number 1457. Available from: https://doi.org/10.1186/s12889-022-13832-3

Falls prevention exercise programmes are evidence-based and recommended for improving physical function in older adults. However, few service evaluations exist to assess the effectiveness of community-delivered interventions in practice. We conducted... Read More about The effectiveness of the Healthworks Staying Steady community-based falls prevention exercise programme to improve physical function in older adults: a 6-year service evaluation..

Changes in patient activation following cardiac rehabilitation using the Active+me digital healthcare platform during the COVID-19 pandemic: a cohort evaluation. (2021)
Journal Article
FRITH, G., CARVER, K., CURRY, S., DARBY, A., SYDES, A., SYMONDS, S., WILSON, K., MCGREGOR, G., AUTON, K. and NICHOLS, S. 2021. Changes in patient activation following cardiac rehabilitation using the Active+me digital healthcare platform during the COVID-19 pandemic: a cohort evaluation. BMC health services research [online], 21, article number 1363. Available from: https://doi.org/10.1186/s12913-021-07363-7

Restrictions on face-to-face contact, due to COVID-19, led to a rapid adoption of technology to remotely deliver cardiac rehabilitation (CR). Some technologies, including Active+me, were used without knowing their benefits. We assessed changes in pat... Read More about Changes in patient activation following cardiac rehabilitation using the Active+me digital healthcare platform during the COVID-19 pandemic: a cohort evaluation..

Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: a CARE CR study. (2021)
Journal Article
NICHOLS, S., ENGIN, B., CARROLL, S., BUCKLEY, J. and INGLE, L. 2021. Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: a CARE CR study. Annals of physical and rehabilitation medicine [online], 64(6), article number 101462. Available from: https://doi.org/10.1016/j.rehab.2020.101462

Exercise prescription guidelines for individuals undergoing cardiovascular rehabilitation (CR) are often based on heart rate training zones and rating of perceived exertion (RPE). United Kingdom guidelines indicate that patients should exercise at an... Read More about Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: a CARE CR study..

Effect of exercise interventions on health-related quality of life after stroke and transient ischemic attack: a systematic review and meta-analysis. (2021)
Journal Article
ALI, A., TABASSUM, D., BAIG, S.S., MOYLE, B., REDGRAVE, J., NICHOLS, S., MCGREGOR, G., EVANS, K., TOTTON, N., COOPER, C. and MAJID, A. 2021. Effect of exercise interventions on health-related quality of life after stroke and transient ischemic attack: a systematic review and meta-analysis. Stroke [online], 52(7), pages 2445-2455. Available from: https://doi.org/10.1161/STROKEAHA.120.032979

Exercise interventions have been shown to help physical fitness, walking, and balance after stroke, but data are lacking on whether such interventions lead to improvements in health-related quality of life (HRQoL). In this systematic review and meta-... Read More about Effect of exercise interventions on health-related quality of life after stroke and transient ischemic attack: a systematic review and meta-analysis..

How has technology been used to deliver cardiac rehabilitation during the COVID-19 pandemic? An international cross-sectional survey of healthcare professionals conducted by the BACPR. (2021)
Journal Article
O'DOHERTY, A.F., HUMPHREYS, H., DAWKES, S., COWIE, A., HINTON, S., BRUBAKER, P.H., BUTLER, T. and NICHOLS, S. 2021. How has technology been used to deliver cardiac rehabilitation during the COVID-19 pandemic? An international cross-sectional survey of healthcare professionals conducted by the BACPR. BMJ open [online], 11(4), article e046051. Available from: https://doi.org/10.1136/bmjopen-2020-046051

Objective: To investigate whether exercise-based cardiac rehabilitation services continued during the COVID-19 pandemic and how technology has been used to deliver home-based cardiac rehabilitation. Design: A mixed methods survey including questions... Read More about How has technology been used to deliver cardiac rehabilitation during the COVID-19 pandemic? An international cross-sectional survey of healthcare professionals conducted by the BACPR..

The influence of resistance training on neuromuscular function in middle-aged and older adults: a systematic review and meta-analysis of randomised controlled trials. (2021)
Journal Article
JAMES, E., NICHOLS, S., GOODALL, S., HICKS, K.M. and O'DOHERTY, A.F. 2021. The influence of resistance training on neuromuscular function in middle-aged and older adults: a systematic review and meta-analysis of randomised controlled trials. Experimental gerontology [online], 149, article number 111320. Available from: https://doi.org/10.1016/j.exger.2021.111320

Deterioration of neuromuscular function is a major mechanism of age-related strength loss. Resistance training (RT) improves muscle strength and mass. However, the effects of RT on neuromuscular adaptations in middle-aged and older adults are unclear... Read More about The influence of resistance training on neuromuscular function in middle-aged and older adults: a systematic review and meta-analysis of randomised controlled trials..

Corrigendum to: Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: a CARE CR study. (2020)
Journal Article
NICHOLS, S., TAYLOR, C., GOODMAN, T., PAGE, R., KALLVIKBACKA-BENNETT, A., NATION, F., CLARK, A.L., BIRKETT, S.T., CARROLL, S. and INGLE, L. 2021. Corrigendum to Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: a CARE CR study. International journal of cardiology [online], 322, page 294. Available from: https://doi.org/10.1016/j.ijcard.2020.08.078

This corrigendum addresses an incorrect reference in the original article.

Characterising the application of the "progressive overload" principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme. (2020)
Journal Article
KHUSHHAL, A., NICHOLS, S., CARROLL, S., ABT, G. and INGLE, L. 2020. Characterising the application of the "progressive overload" principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme. PLoS ONE (online), 15(8), article number e0237197. Available from: https://doi.org/10.1371/journal.pone.0237197

Recent concerns have cast doubt over the effectiveness of cardiac rehabilitation (CR) programmes for improving cardiorespiratory fitness (CRF) in patients with a history of cardiac disease in the United Kingdom (UK). Through an observational study, w... Read More about Characterising the application of the "progressive overload" principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme..

Current insights into exercise-based cardiac rehabilitation in patients with coronary heart disease and chronic heart failure. (2020)
Journal Article
NICHOLS, S., MCGREGOR, G., BRECKON, J. and INGLE, L. 2021. Current insights into exercise-based cardiac rehabilitation in patients with coronary heart disease and chronic heart failure. International journal of sports medicine [online], 42(01), pages 19-26. Available from: https://doi.org/10.1055/a-1198-5573

Cardiac rehabilitation is a package of lifestyle secondary prevention strategies designed for patients with coronary heart disease and chronic heart failure. A community-based cardiac rehabilitation programme provides patients with a structured exerc... Read More about Current insights into exercise-based cardiac rehabilitation in patients with coronary heart disease and chronic heart failure..

COVID-19 and cardiac rehabilitation. (2020)
Journal Article
DAWKES, S., HUGHES, S., RAY, S., NICHOLS, S., HINTON, S., ROBERTS, C., BUTLER, T., DELAL, H. and DOCHERTY, P. 2020. COVID-19 and cardiac rehabilitation. British journal of cardiology [online], 27(2), page 50. Available from: https://doi.org/10.5837/bjc.2020.019

The British Association for Cardiovascular Prevention and Rehabilitation (BACPR), the British Cardiovascular Society (BCS) and the British Heart Foundation (BHF) have issued a joint position statement "Retention of cardiac rehabilitation services dur... Read More about COVID-19 and cardiac rehabilitation..