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All Outputs (134)

Studies on the role of zinc in maintaining antioxidant status in the heart. (2020)
Thesis
OKAFOR, O.A.G. 2020. Studies on the role of zinc in maintaining antioxidant status in the heart. Robert Gordon University, MRes thesis. Hosted on OpenAIR [online]. Available from: https://openair.rgu.ac.uk

Zinc (Zn2+) is an essential micronutrient which plays a pivotal role as a signalling, catalytic and structural component in cells and functions in several physiological processes such as immune function, wound healing, cognition, reproduction and as... Read More about Studies on the role of zinc in maintaining antioxidant status in the heart..

Exploring medication error causality and reporting in the Middle East. (2019)
Thesis
THOMAS, B. 2019. Exploring medication error causality and reporting in the Middle East. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

The "Medication Without Harm, WHO Global Patient Safety Challenge", published by the World Health Organization in 2017, calls for action to reduce patient harm as a result of unsafe medication practices and medication errors. Medication error-related... Read More about Exploring medication error causality and reporting in the Middle East..

The development of an electrochemical sensing device for controlled drugs. (2019)
Thesis
WADDELL, S.A. 2019. The development of an electrochemical sensing device for controlled drugs. Robert Gordon University, PhD thesis. Hosted on OpenAIR [online]. Available from: https://doi.org/10.48526/rgu-wt-1677791

Forensic chemists can be faced with a wide array of substances to test when attending clandestine drug manufacture crime scenes. Whilst many techniques exist at their disposal - such as chemical colour test reagents and immunoassays - these methods a... Read More about The development of an electrochemical sensing device for controlled drugs..

Effectiveness and acceptability of two dietary interventions in African women in diaspora. (2019)
Thesis
ADEBOYE, B.O. 2019. Effectiveness and acceptability of two dietary interventions in African women in diaspora. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

Obesity disproportionally affects women of ethnic minorities, especially those of African descent, living in the United Kingdom (UK). The Organisation for Economic Co-operation and Development (OECD) has estimated that obesity rates are 13% higher am... Read More about Effectiveness and acceptability of two dietary interventions in African women in diaspora..

Synthesis of novel vanillin derivatives: study of their antioxidant and potential neuroprotective properties. (2019)
Thesis
SCIPIONI, M. 2019. Synthesis of novel vanillin derivatives: study of their antioxidant and potential neuroprotective properties. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

Vanillin (4-hydroxy-3-methoxybenzaldehyde) is a naturally-occurring phenolic compound, forming the main component of the bean and pod of vanilla orchids. It is widely used as a flavouring agent in food and drinks, and as a preservative in the cosmeti... Read More about Synthesis of novel vanillin derivatives: study of their antioxidant and potential neuroprotective properties..

Exploring the obesogenic environment: understanding the health impact of contemporary living. (2019)
Thesis
SIBSON, R.H. 2019. Exploring the obesogenic environment: understanding the health impact of contemporary living. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

Obesity exists in the complexity of everyday life and arises from individuals' interactions with the obesogenic environment, different behaviours/dispositions and biological factors. In order to develop better intervention strategies to attenuate obe... Read More about Exploring the obesogenic environment: understanding the health impact of contemporary living..

Exploring the potential resource recovery from pot ale utilising microalgae and novel LED photobioreactors. (2019)
Thesis
MCNERNEY, C.C. 2019. Exploring the potential resource recovery from pot ale utilising microalgae and novel LED photobioreactors. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

Pot ale is a protein-rich, high-carbon and acidic (pH 3.5) by-product of the whisky industry. With 4.9 million tonnes of pot ale being produced per annum in Scotland alone, it presents a difficult disposal challenge for the industry. Pot ale has high... Read More about Exploring the potential resource recovery from pot ale utilising microalgae and novel LED photobioreactors..

A study of the development of frameworks of pharmacist prescribing in Qatar. (2019)
Thesis
JEBARA, T. 2019. A study of the development of frameworks of pharmacist prescribing in Qatar. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

Several countries across the world have developed and implemented frameworks of non-medical prescribing. In the United Kingdom, pharmacist prescribing was introduced in 2003 as supplementary prescribing, with this extended to include independent pres... Read More about A study of the development of frameworks of pharmacist prescribing in Qatar..

An investigation into the molecular mechanisms of hyperbaric oxygen using a human dermal microvascular endothelial cell line and a porcine retinal explant model. (2019)
Thesis
IWUAGWU, B.U. 2019. An investigation into the molecular mechanisms of hyperbaric oxygen using a human dermal microvascular endothelial cell line and a porcine retinal explant model. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

Diabetes is a debilitating metabolic condition with associated vascular complications that are a major cause of morbidity and mortality. Endothelial dysfunction is central to microvascular complications such as diabetic retinopathy (DR) and impaired... Read More about An investigation into the molecular mechanisms of hyperbaric oxygen using a human dermal microvascular endothelial cell line and a porcine retinal explant model..

An exploration of the medication related experiences of community dwelling adults with learning disabilities. (2019)
Thesis
MACLEOD, J. 2019. An exploration of the medication related experiences of community dwelling adults with learning disabilities. Robert Gordon University [online], DPP thesis. Available from: https://openair.rgu.ac.uk

The purpose of this study was to explore the medication related experiences of community dwelling adults with learning disabilities (LD). A narrative review was undertaken and found that current literature focused on measuring the prevalence of parti... Read More about An exploration of the medication related experiences of community dwelling adults with learning disabilities..

The potential application of rapeseed pomace extracts in the prevention and treatment of neurodegenerative diseases. (2019)
Thesis
POHL, F. 2019. The potential application of rapeseed pomace extracts in the prevention and treatment of neurodegenerative diseases. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

Rapeseed pomace (RSP) is the waste/by-product obtained after edible oil production from Brassica napus and is currently used as animal feed. In an attempt to revalorize this by-product as a potential nutraceutical for the treatment or prevention of n... Read More about The potential application of rapeseed pomace extracts in the prevention and treatment of neurodegenerative diseases..

An investigation of genetic polymorphism in association with Type 2 diabetes and metabolic syndrome. (2018)
Thesis
BHATTA, P. 2018. An investigation of genetic polymorphism in association with Type 2 diabetes and metabolic syndrome. Robert Gordon University, PhD thesis.

Type 2 diabetes and metabolic syndrome are the metabolic disorders which constitute a major public health problem in both developed and developing countries. Various studies have suggested the genetic susceptibility to the disorders. The main aim of... Read More about An investigation of genetic polymorphism in association with Type 2 diabetes and metabolic syndrome..

Determining the role of the LPI/GPR55 system in the development of obesity and associated cardiovascular consequences. (2018)
Thesis
HAIR, S.C. 2018. Determining the role of the LPI/GPR55 system in the development of obesity and associated cardiovascular consequences. Robert Gordon University, PhD thesis.

Obesity has reached worldwide epidemic proportions and with this increased incidence of obesity, comes an increase in incidence of the comorbidities associated with obesity such as diabetes and cardiovascular disease (CVD). The underlying mechanisms... Read More about Determining the role of the LPI/GPR55 system in the development of obesity and associated cardiovascular consequences..

Targeting histone deacetylase (HDACs) enzymes with novel bisnaphthalimidopropyl derivatives (BNIPs) as alternative breast cancer therapies. (2018)
Thesis
KOPSIDA, M. 2018. Targeting histone deacetylase (HDACs) enzymes with novel bisnaphthalimidopropyl derivatives (BNIPs) as alternative breast cancer therapies. Robert Gordon University, PhD thesis.

Breast cancer is the most commonly occurring cancer in women, with incidence rates approaching 1.38 million cases per year worldwide. Over the last few decades, there have been numerous attempts to develop, synthesise and advance into the clinic nove... Read More about Targeting histone deacetylase (HDACs) enzymes with novel bisnaphthalimidopropyl derivatives (BNIPs) as alternative breast cancer therapies..

An investigation and examination of the levels and types of bacterial contamination on the surface of clean room operators' garments. (2018)
Thesis
SMITH, L.M. 2018. An investigation and examination of the levels and types of bacterial contamination on the surface of clean room operators' garments. Robert Gordon University, PhD thesis.

The contamination of sterile pharmaceutical products is a serious event which has in the worst case scenario led to patient death. Operators are the primary source of clean room contamination, with the majority of their detritus being identified as s... Read More about An investigation and examination of the levels and types of bacterial contamination on the surface of clean room operators' garments..

Studies on the role of GPR55 in cardiovascular physiology and pathophysiology. (2017)
Thesis
ROBERTSON-GRAY, O.J. 2017. Studies on the role of GPR55 in cardiovascular physiology and pathophysiology. Robert Gordon University, PhD thesis.

Atherosclerosis is a multifactorial, chronic inflammatory condition characterised by endothelial dysfunction, hyperlipidaemia and the accumulation of fatty deposits within the tunica intima of medium-to-large sized muscular arteries. This disease can... Read More about Studies on the role of GPR55 in cardiovascular physiology and pathophysiology..

Exploring the facilitators and barriers towards implementation of electronic prescribing, dispensing, and administration of medicines in hospitals in Ireland. (2017)
Thesis
HOGAN-MURPHY, D. 2017. Exploring the facilitators and barriers towards implementation of electronic prescribing, dispensing, and administration of medicines in hospitals in Ireland. Robert Gordon University, PhD thesis.

Limited data exist on the facilitators and barriers to implementing electronic systems for medicines management in hospitals. Whilst numerous studies advocate system use in improved patient safety and efficiency within the health service, their rate... Read More about Exploring the facilitators and barriers towards implementation of electronic prescribing, dispensing, and administration of medicines in hospitals in Ireland..

The effect of single nucleotide polymorphisms and metabolic substrates on the cellular distribution of mammalian BK channels. (2017)
Thesis
ADEYILEKA-TRACZ, B.A. 2017. The effect of single nucleotide polymorphisms and metabolic substrates on the cellular distribution of mammalian BK channels. Robert Gordon University, PhD thesis.

Humans are approximately 99% similar with inter-individual differences caused in part by single-nucleotide polymorphisms (SNPs), which poses a challenge for the effective treatment of disease. Bioinformatics resources can help to store and analyse ge... Read More about The effect of single nucleotide polymorphisms and metabolic substrates on the cellular distribution of mammalian BK channels..

Social and cognitive influences on prescribing decisions among non-medical prescribers. (2017)
Thesis
MCINTOSH, T. 2017. Social and cognitive influences on prescribing decisions among non-medical prescribers. Robert Gordon University, PhD thesis.

Non-medical prescribers make an increasing contribution to healthcare across the UK yet little is known about influences on their prescribing decision-making. The aim of this programme of research was to explore and describe prescribing decision-maki... Read More about Social and cognitive influences on prescribing decisions among non-medical prescribers..

The design, synthesis and evaluation of selective, non invasive imaging agents for atherosclerotic plaque. (2017)
Thesis
JESUDOSS, J.R. 2017. The design, synthesis and evaluation of selective, non invasive imaging agents for atherosclerotic plaque. Robert Gordon University, MPhil thesis.

The aim of this research study was the synthesis of an imaging agent, which could be used to non-invasively image atherosclerotic plaques via MRI. In order to achieve this, a library of peptide substrates designed to be substrate specific for either... Read More about The design, synthesis and evaluation of selective, non invasive imaging agents for atherosclerotic plaque..