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Evidence for functional drift of bacterial isolates in response to cyanobacterial microcystin-lr and multiple peptide degradation in paucibacter toxinivorans. (2016)
Thesis
KREITZ, J. 2016. Evidence for functional drift of bacterial isolates in response to cyanobacterial microcystin-lr and multiple peptide degradation in paucibacter toxinivorans. Robert Gordon University, MPhil thesis.

Bacterial bioremediation has been proposed as an efficient, low cost and ecologically safe method to clean vital water reservoirs from cyanobacterial peptide toxins microcystins (MCs). In previous work carried out in 2008 several bacteria were isolat... Read More about Evidence for functional drift of bacterial isolates in response to cyanobacterial microcystin-lr and multiple peptide degradation in paucibacter toxinivorans..

Characterisation of cysteamine prodrugs for the treatment of cystinosis and evaluation of liquid fill technology. (2016)
Thesis
MCCORMICK, J.J. 2016. Characterisation of cysteamine prodrugs for the treatment of cystinosis and evaluation of liquid fill technology. Robert Gordon University, MRes thesis.

Cystinosis is a rare, autosomal, recessive disease characterised by raised levels of the amino acid cystine in the cells of most organs in the body which can cause organ damage. The treatment involves the oral administration of the aminothiol, cystea... Read More about Characterisation of cysteamine prodrugs for the treatment of cystinosis and evaluation of liquid fill technology..

An investigation on the effects of cyanopeptides on the growth and secondary metabolite production of Microcystis aeruginosa PCC7806. (2016)
Thesis
ARIF ABDUL RAHMAN, T. 2016. An investigation on the effects of cyanopeptides on the growth and secondary metabolite production of Microcystis aeruginosa PCC7806. Robert Gordon University, PhD thesis.

Cyanobacteria are one of the oldest forms of photosynthetic life and may have contributed significantly to the evolution of oxygen into the then anoxic environment. Cyanobacteria are also one of the best sources of natural secondary metabolites (cyan... Read More about An investigation on the effects of cyanopeptides on the growth and secondary metabolite production of Microcystis aeruginosa PCC7806..

Role of nuclear factor kappa B (NFkB) in the vascular complications of diabetes. (2016)
Thesis
AL ALI, F.M. 2016. Role of nuclear factor kappa B (NFkB) in the vascular complications of diabetes. Robert Gordon University, MRes thesis.

Diabetes mellitus (DM) is the most common metabolic disease worldwide. This condition accounts for the majority of renal failure and blindness in adults aged between 20 to 74 years of age. After 20 years, some of type 1 diabetic patients and around 6... Read More about Role of nuclear factor kappa B (NFkB) in the vascular complications of diabetes..

Hospital electronic prescribing and medicines administration system implementation into a district general hospital: a mixed method evaluation of discharge communication. (2016)
Thesis
MILLS, P.R. 2016. Hospital electronic prescribing and medicines administration system implementation into a district general hospital: a mixed method evaluation of discharge communication. Robert Gordon University, DPP thesis.

Hospital electronic prescribing and medicines administration (HEPMA) system implementation is advocated by national e-health strategies to produce patient safety benefits. No previous study has evaluated the impact of HEPMA implementation on either d... Read More about Hospital electronic prescribing and medicines administration system implementation into a district general hospital: a mixed method evaluation of discharge communication..

Exploring structures and processes of medicines management in elderly hospitalised patients in the United Arab Emirates. (2015)
Thesis
AL SHEMEILI, S.K. 2015. Exploring structures and processes of medicines management in elderly hospitalised patients in the United Arab Emirates. Robert Gordon University, PhD thesis.

Given the complexity of medicines use in elderly patients, structures and processes of medicines management are key to deriving best outcomes. This research was conducted in hospitals in the United Arab Emirates (UAE) and focused on the patient journ... Read More about Exploring structures and processes of medicines management in elderly hospitalised patients in the United Arab Emirates..

A novel polyelectrolyte complex between amphiphilic poly (allyl amine) and sodium alginate. (2015)
Thesis
SARTAWI, Z. 2015. A novel polyelectrolyte complex between amphiphilic poly (allyl amine) and sodium alginate. Robert Gordon University, MRes Thesis.

Polyelectrolytes are charge-carrying polymers. When two oppositely-charged polyelectrolytes are combined in a solution favouring charge expression, a polyelectrolyte complex can result. These complexes have been shown to be useful in the field of dru... Read More about A novel polyelectrolyte complex between amphiphilic poly (allyl amine) and sodium alginate..

User-perceived effectiveness and safety of paediatric complementary and alternative medicines: perspectives from international, British and local Scottish outcomes studies. (2015)
Thesis
NDU, O.O. 2015. User-perceived effectiveness and safety of paediatric complementary and alternative medicines: perspectives from international, British and local Scottish outcomes studies. Robert Gordon University, PhD thesis.

In the light of the current patient-centred approach to healthcare delivery, this research investigated the effectiveness and safety of paediatric complementary and alternative medicines (CAMs) from the users' perspective in order to generate suitabl... Read More about User-perceived effectiveness and safety of paediatric complementary and alternative medicines: perspectives from international, British and local Scottish outcomes studies..

The design and synthesis of novel pro-drugs for the treatment of nephropathic cystinosis. (2015)
Thesis
BAHMED, A. 2015. The design and synthesis of novel pro-drugs for the treatment of nephropathic cystinosis. Robert Gordon University, PhD thesis.

Cystinosis is a metabolic disorder characterised by the abnormal accumulation of the amino acid cystine in cells leading to a slow destruction of all major organs. If patients diagnosed with cystinosis are untreated, death due to kidney failure ensue... Read More about The design and synthesis of novel pro-drugs for the treatment of nephropathic cystinosis..

A mixed methods investigation into aspects of medication wastage in Malta. (2015)
Thesis
WEST, L.M. 2015. A mixed methods investigation into aspects of medication wastage in Malta. Robert Gordon University, PhD thesis.

Reducing medication wastage is a paramount objective in promoting appropriate utilisation of finite resources and preventing negative consequences. The aim of this research was to investigate aspects of medication wastage in Malta by applying mixed m... Read More about A mixed methods investigation into aspects of medication wastage in Malta..

Overcoming the seasonal variations in fitness of the amphipod Corophium Volutator as an environmental toxicology test species using laboratory cultured specimens. (2014)
Thesis
MCGEE, D. 2014. Overcoming the seasonal variations in fitness of the amphipod Corophium Volutator as an environmental toxicology test species using laboratory cultured specimens. Robert Gordon University, MRes thesis.

The marine amphipod Corophium volutator is an important source of food for many fish and wading birds, making it an important species in an estuarine environment and a relevant toxicological test species. Historical data has indicated that seasonal v... Read More about Overcoming the seasonal variations in fitness of the amphipod Corophium Volutator as an environmental toxicology test species using laboratory cultured specimens..

Studies investigating the mechanisms of the cardioprotective effects of Cannabidiol. (2014)
Thesis
HEPBURN, C.Y. 2014. Studies investigating the mechanisms of the cardioprotective effects of Cannabidiol. Robert Gordon University, PhD thesis.

The phytocannabinoid cannabidiol (CBD) has a complex pharmacology which is thought to include, but is not limited to, an ability to act as an inverse agonist at the CB1 and CB2 receptors and an antagonist of GPR55. Moreover, is has been shown to redu... Read More about Studies investigating the mechanisms of the cardioprotective effects of Cannabidiol..

Optimisation of high value metabolite production from benthic marine dinoflagellate Prorocentrum lima. (2014)
Thesis
PRAPTIWI, R.A. 2014. Optimisation of high value metabolite production from benthic marine dinoflagellate Prorocentrum lima. Robert Gordon University, PhD thesis.

Toxins produced by harmful algal blooms (HABs) are known to pose contamination risks to seafood products (e.g. fish and shellfish) consumed by human. In order to control contamination risks, monitoring regimes have to be performed rigorously. The eff... Read More about Optimisation of high value metabolite production from benthic marine dinoflagellate Prorocentrum lima..

An exploration of ehealth and digital literacy in pharmacy practice. (2014)
Thesis
MACLURE, K. 2014. An exploration of ehealth and digital literacy in pharmacy practice. Robert Gordon University, PhD thesis.

The aim of this research programme was to explore ehealth technology in pharmacy practice in Scotland and, by doing so, contribute original knowledge to this area. Strategists worldwide believe technology has the potential to promote quality, safety... Read More about An exploration of ehealth and digital literacy in pharmacy practice..

Novel polyelectrolyte complexes for oral insulin delivery. (2013)
Thesis
IBIE, C.O. 2013. Novel polyelectrolyte complexes for oral insulin delivery. Robert Gordon University, PhD thesis.

Oral delivery of insulin used for the management of Type 1 diabetes could be referred to as one of the major long-term goals of diabetes research. However, the bioavailability of orally-administrered insulin is significantly compromised by enzymatic... Read More about Novel polyelectrolyte complexes for oral insulin delivery..

Examination of the antibacterial activities of some semi-synthetic chalcone-derivatives alone and in combination with polymyxin B. (2013)
Thesis
MEDU, E.O. 2013. Examination of the antibacterial activities of some semi-synthetic chalcone-derivatives alone and in combination with polymyxin B. Robert Gordon University, PhD thesis.

Bacterial resistance is an increasing challenge across the world, which means that there is an urgent need for the rational development of antibacterial compounds that have either novel or multiple mechanisms of action. This study demonstrated that t... Read More about Examination of the antibacterial activities of some semi-synthetic chalcone-derivatives alone and in combination with polymyxin B..

Combined effects of bioavailable organic contaminants in the aquatic environment. (2013)
Thesis
EMELOGU, E.S. 2013. Combined effects of bioavailable organic contaminants in the aquatic environment. Robert Gordon University, PhD thesis.

In contrast to conventional spot or bottle water sampling techniques, passive sampling has been shown to be a reliable and efficient method for monitoring the toxicologically-relevant, freely-dissolved (e.g. bioavaialable) concentrations of a wide ra... Read More about Combined effects of bioavailable organic contaminants in the aquatic environment..

Investigation of the production and isolation of bioactive compounds from cyanobacteria. (2013)
Thesis
HAMEED, S. 2013. Investigation of the production and isolation of bioactive compounds from cyanobacteria. Robert Gordon University, PhD thesis.

Due to heavy nutrient load and adverse climate change the occurrence of toxic cyanobacterial blooms have significantly increased during the last decades. Nodularia spumigena is one of the dominant toxic cyanobacteria which produces massive and inhere... Read More about Investigation of the production and isolation of bioactive compounds from cyanobacteria..

Freshwater bacterial diversity, functions and stability. (2013)
Thesis
GIARAMIDA, L. 2013. Freshwater bacterial diversity, functions and stability. Robert Gordon University, PhD thesis.

Biodiversity is declining worldwide with detrimental effects on ecosystems functions and services that it sustains. The relationship between biodiversity and freshwater purification remains unclear. Freshwater purification is of paramount importance... Read More about Freshwater bacterial diversity, functions and stability..

Investigation of novel methods to remove the cyanotoxin, Cylindrospermopsin, from drinking water. (2013)
Thesis
CHANDU, V.C.P 2013. Investigation of novel methods to remove the cyanotoxin, Cylindrospermopsin, from drinking water. Robert Gordon University, PhD thesis.

The widespread distribution of cyanobacteria and their toxic effects on humans has become a major concern for researchers. Cyanobacteria are a group of oxygenic phototrophic bacteria that exhibit an enormous diversity in shapes and arrangements and o... Read More about Investigation of novel methods to remove the cyanotoxin, Cylindrospermopsin, from drinking water..