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Environmental risk management of contamination of marine biota by hydrocarbons specifically those arising following an oil spill. (2009)
Thesis
ENWERE, R. 2009. Environmental risk management of contamination of marine biota by hydrocarbons specifically those arising following an oil spill. Robert Gordon University, PhD thesis.

Marine pollution resulting from oil spillage has received much attention mostly due to the damaging effects it has on fisheries and aquacultures. One component of oil that is widely studied due to its toxic and carcinogenic properties is the polycycl... Read More about Environmental risk management of contamination of marine biota by hydrocarbons specifically those arising following an oil spill..

Cellular mechanisms of acute hypoxic pulmonary vasoconstriction in intrapulmonary veins. (2009)
Thesis
DOSPINESCU, C. 2009. Cellular mechanisms of acute hypoxic pulmonary vasoconstriction in intrapulmonary veins. Robert Gordon University, PhD thesis.

In the pulmonary circulation, alveolar hypoxia contributes to blood flow regulation. Hypoxic pulmonary vasoconstriction (HPV) involves both pulmonary arteries and veins, but little is known of the contractile mechanisms specific to the veins. The aim... Read More about Cellular mechanisms of acute hypoxic pulmonary vasoconstriction in intrapulmonary veins..

Investigation of exopolysaccharide production by lactic acid bacteria. (2008)
Thesis
JONES, R.A. 2008. Investigation of exopolysaccharide production by lactic acid bacteria. Robert Gordon University, PhD thesis.

This thesis is an investigation into the production of exopolysaccharides (EPS) produced by strains of Lactobacillus delbrueckii ssp. bulgaricus and Lactococcus lactis ssp. cremoris. These are used in the dairy industry for the production of yoghurt... Read More about Investigation of exopolysaccharide production by lactic acid bacteria..

The effect of CLAs on the expression of PKC isoforms and cell viability in breast cancer cell lines. (2008)
Thesis
CRABB-WYKE, R. 2008. The effect of CLAs on the expression of PKC isoforms and cell viability in breast cancer cell lines. Robert Gordon University, MPhil thesis.

Breast tumours make up 15% of the total cancer burden in the UK and around 8% of the total number of cancer related deaths. Protein kinase C (PKC) isoforms have been shown to be strongly modulated in many androgen sensitive tumour cell lines. Increas... Read More about The effect of CLAs on the expression of PKC isoforms and cell viability in breast cancer cell lines..

Cytochrome P450 mRNA profile in human breast cancer cell lines. (2008)
Thesis
WARASIHA, B. 2008. Cytochrome P450 mRNA profile in human breast cancer cell lines. Robert Gordon University, PhD thesis.

Cytochrome P450 enzymes (P450s) are involved in cancer development and treatment due to their roles in the oxidative metabolism of various compounds, both endogenous (e.g. oestrogen) and exogenous (e.g. tamoxifen). Intermediate P450 metabolites deriv... Read More about Cytochrome P450 mRNA profile in human breast cancer cell lines..

Investigation of hypoxia and hyperglycaemia mediated DNA damage in human endothelial cells. (2008)
Thesis
WEIDMANN, A.E. 2008. Investigation of hypoxia and hyperglycaemia mediated DNA damage in human endothelial cells. Robert Gordon University, PhD thesis.

Chronic complications of diabetes mellitus are a pathological consequence of unregulated levels of blood glucose leading to disorders of the vascular system. When investigating the vascular complications the changes in the endothelium are of particul... Read More about Investigation of hypoxia and hyperglycaemia mediated DNA damage in human endothelial cells..

Bioavailability of organic contaminants in sediments. (2008)
Thesis
YATES, K. 2008. Bioavailability of organic contaminants in sediments. Robert Gordon University, PhD thesis.

The bioavailability of polycyclic aromatic hydrocarbons (PAHs) and chlorobiphenyls (CBs) in sediments is largely dependent on the freely dissolved concentration of these pollutants. However, measuring these is challenging, due to the low concentratio... Read More about Bioavailability of organic contaminants in sediments..

Biomarkers of oxidative stress in models of schizophrenia. (2007)
Thesis
YOUNG, J., 2007. Biomarkers of oxidative stress in models of schizophrenia. Robert Gordon University, PhD thesis.

Increasing evidence indicates that oxidative injury exists in schizophrenia. Although it may not be the main cause, oxidative damage has been suggested to contribute to the pathophysiology and may account for deteriorating course and poor outcome in... Read More about Biomarkers of oxidative stress in models of schizophrenia..

Evaluation of the quality of individual quick frozen fish products. (2007)
Thesis
SEREMETI, M.M. 2007. Evaluation of the quality of individual quick frozen fish products. Robert Gordon University, PhD thesis.

In the present study the effects of characteristic freezing times and storage time at -22°C on the quality of the adductor muscle of post-rigor scallops (Pecten maximus)and gilthead seabream fillets (Sparusa urata) were studied in regard to the integ... Read More about Evaluation of the quality of individual quick frozen fish products..

Degradation of microcystin-LR by aquatic bacteria. (2007)
Thesis
GHIMIRE, B.S. 2007. Degradation of microcystin-LR by aquatic bacteria. Robert Gordon University, PhD thesis.

Microcystins are cyclic heptapeptide toxins produced by cyanobacteria. They are potentially a threat to human and domestic animals so are of worldwide interest. Microcystin-LR is stable in various environmental conditions. It is important to know the... Read More about Degradation of microcystin-LR by aquatic bacteria..

An investigation into factors influencing the production and degradation of microcystins. (2007)
Thesis
GRAHAM, D.J.L. 2007. An investigation into factors influencing the production and degradation of microcystins. Robert Gordon University, PhD thesis.

Microcystins (MCYST) potently inhibit protein phosphatases and these cyclic heptapeptides are powerful hepatotoxins. They are known to be secondary metabolites produced by several species of cyanobacteria. The release of these peptides into water sup... Read More about An investigation into factors influencing the production and degradation of microcystins..

Detection, analysis, and photocatalytic destruction of the freshwater taint compound geosmin. (2007)
Thesis
BELLU, E. 2007. Detection, analysis, and photocatalytic destruction of the freshwater taint compound geosmin. Robert Gordon University, PhD thesis.

A significant issue affecting the aquaculture and water industries is the presence of off-flavour compounds in water, which cause problems by imparting an undesirable earthy/musty flavour and smell to water and fish. Two predominant off-flavour compo... Read More about Detection, analysis, and photocatalytic destruction of the freshwater taint compound geosmin..

Molecular mechanisms of nutrient mediated regulation of hypoxia inducible factor -1a(HIF-1a) in endothelial cells. (2007)
Thesis
HECTOR, E.E. 2007. Molecular mechanisms of nutrient mediated regulation of hypoxia inducible factor -1a(HIF-1a) in endothelial cells. Robert Gordon University, PhD thesis.

Poorly-controlled diabetes mellitus is associated with the development of chronic vascular complications, which cause morbidity and premature mortality. Many studies have highlighted that maintenance of normal blood glucose levels in all people with... Read More about Molecular mechanisms of nutrient mediated regulation of hypoxia inducible factor -1a(HIF-1a) in endothelial cells..

Cytotoxic compounds from the genus Centaurea. (2005)
Thesis
SHOEB, M. 2005. Cytotoxic compounds from the genus Centaurea. Robert Gordon University, PhD thesis.

This thesis, which is divided into four chapters, represents an account on the isolation, identification and the assessment of bioactivity of cytotoxic compounds from the genus Centaurea (Family: Asteraceae alto Compositae), a large genus of about 50... Read More about Cytotoxic compounds from the genus Centaurea..

The development and application of statistical sampling regime to map out hydrocarbons in sediments. (2005)
Thesis
AHMED, A.S. 2005. The development and application of statistical sampling regime to map out hydrocarbons in sediments. Robert Gordon University, PhD thesis.

This thesis investigates and develops a stratified random sampling design for sediments in an offshore oil field environment. The sampling area was partitioned equally into sixteen zones. Stratification was based on the near-field and far-field areas... Read More about The development and application of statistical sampling regime to map out hydrocarbons in sediments..

Alternative strategies for security labelling/encoding of paper and plastic products. (2005)
Thesis
OFFICER, S.J. 2005. Alternative strategies for security labelling/encoding of paper and plastic products. Robert Gordon University, PhD thesis.

A literature and patent review of current optical security techniques has been carried out and identified a need in the market for an improved optical security label to rival molecular fluorescent dyes. The label proposed was a rare earth (RE) doped... Read More about Alternative strategies for security labelling/encoding of paper and plastic products..

School-based drug education in Northeast Scotland: policy, planning and practice. (2003)
Thesis
FITZGERALD, N. 2003. School-based drug education in Northeast Scotland: policy, planning and practice. Robert Gordon University, PhD thesis.

This research utilised qualitative methods to gain a deeper insight into the policy, planning and practice of school-based drug education than had previously been achieved in Scotland. Semi-structured interviews were carried out with staff in nine Gr... Read More about School-based drug education in Northeast Scotland: policy, planning and practice..

The managed entry of new drugs into a National Health Service: a case study for Malta. (2003)
Thesis
BONANNO, P.V. 2003. The managed entry of new drugs into a National Health Service: a case study for Malta. Robert Gordon University, PhD thesis.

The research question was to determine if it is possible to develop a systematic approach to the managed entry of new drugs into a National Health Service( NHS), using Malta as a case study. In early 1999, Malta had major problems with the managed en... Read More about The managed entry of new drugs into a National Health Service: a case study for Malta..

Purification and characterisation of the lipid macroamphiphiles of propionibacterium acnes. (2002)
Thesis
WHALE, G.A. 2002. Purification and characterisation of the lipid macroamphiphiles of propionibacterium acnes. Robert Gordon University, PhD thesis. Hosted on OpenAIR [online]. Available from: https://doi.org/10.48526/rgu-wt-1905093

Lipid macroamphiphiles (LMAPs) are cell envelope components of bacteria that have been extensively associated with the pathogenesis of disease. It has been reported that these components can also influence the in vivo metabolism of lipids in mammals.... Read More about Purification and characterisation of the lipid macroamphiphiles of propionibacterium acnes..

Assessing pharmacist's intervention in supporting the management of Type 2 diabetes in a primary care setting. (2002)
Thesis
SOORAPAN, S. 2002. Assessing pharmacist's intervention in supporting the management of Type 2 diabetes in a primary care setting. Robert Gordon University, PhD thesis.

Type 2 diabetes mellitus is a chronic disease that is associated with substantial morbidity, mortality, and health care cost. All patients with diabetes require a high level of clinical care to prevent the development of diabetic complications. The a... Read More about Assessing pharmacist's intervention in supporting the management of Type 2 diabetes in a primary care setting..