All Outputs (2)

Cytochrome P450 mRNA profile in human breast cancer cell lines. (2008)
Thesis
WARASIHA, B. 2008. Cytochrome P450 mRNA profile in human breast cancer cell lines. Robert Gordon University, PhD thesis.

Cytochrome P450 enzymes (P450s) are involved in cancer development and treatment due to their roles in the oxidative metabolism of various compounds, both endogenous (e.g. oestrogen) and exogenous (e.g. tamoxifen). Intermediate P450 metabolites deriv... Read More about Cytochrome P450 mRNA profile in human breast cancer cell lines..

Investigation of hypoxia and hyperglycaemia mediated DNA damage in human endothelial cells. (2008)
Thesis
WEIDMANN, A.E. 2008. Investigation of hypoxia and hyperglycaemia mediated DNA damage in human endothelial cells. Robert Gordon University, PhD thesis.

Chronic complications of diabetes mellitus are a pathological consequence of unregulated levels of blood glucose leading to disorders of the vascular system. When investigating the vascular complications the changes in the endothelium are of particul... Read More about Investigation of hypoxia and hyperglycaemia mediated DNA damage in human endothelial cells..