All Outputs (4)

Assessment of a putative oncogene ZNF217 in colorectal cancer by multiplex quantitative real-time PCR. (2002)
Presentation / Conference Contribution
ROONEY, P.H., BOONSONG, A., MCFADYEN, M., MCLEOD, H.L., CASSIDY, J. and MURRAY, G.I. 2002. Assessment of a putative oncogene ZNF217 in colorectal cancer by multiplex quantitative real-time PCR. Presented at the 184th Meeting of the Pathological Society of Great Britain and Ireland, 2-5 July 2002, Dublin, Ireland.

Detection of gene amplification is a process that is recognised as a means of identifying oncogenes. This presentation discusses a study in which the gene copy number of a putative oncogene (ZNF217) was assessed in 80 colon carcinomas by multiplex qu... Read More about Assessment of a putative oncogene ZNF217 in colorectal cancer by multiplex quantitative real-time PCR..

Quantitative analysis of the Ah receptor signalling pathway. (2002)
Presentation / Conference Contribution
MCFADYEN, M.C.E., ROONEY, P.H. and MURRAY, G.I. 2002. Quantitative analysis of the Ah receptor signalling pathway. Presented at the 2002 British cancer research meeting (BCRM 2002), 30 June - 3 July 2002, Glasgow, UK.

The aryl hydrocarbon receptor (AhR) is a ligand activated receptor. On dimerisation with the aryl hydrocarbon nuclear translocator (ARNT), AhR binds to xenobiotic responsive elements (XREs) that promote the activation of a battery of genes, including... Read More about Quantitative analysis of the Ah receptor signalling pathway..

Assessment of a putative oncogene ZNF217 within amplicon 20q by multiplex quantitative real-time PCR. (2002)
Presentation / Conference Contribution
ROONEY, P., BOONSONG, A., MCFADYEN, M., MCLEOD, H.L., CASSIDY, J. and MURRAY, G.I. 2002. Assessment of a putative oncogene ZNF217 within amplicon 20q by multiplex quantitative real-time PCR. Presented at the 2002 British cancer research meeting (BCRM 2002), 30 June - 3 July 2002, Glasgow, UK.

Detection of gene amplification is a recognised process through which oncogenes can be identified. In this study, we have coupled two powerful techniques - laser capture-microdissection and multiplex quantitative real-time PCR - to quickly and accura... Read More about Assessment of a putative oncogene ZNF217 within amplicon 20q by multiplex quantitative real-time PCR..

Metabolically active cytochrome P450 CYP1B1 in solid tumours: a novel target for chemotherapeutic intervention. (2002)
Presentation / Conference Contribution
MCFADYEN, M.C.E., MELVIN, W.T. and MURRAY, G.I. 2002. Metabolically active cytochrome P450 CYP1B1 in solid tumours: a novel target for chemotherapeutic intervention. Presented at the 2002 British cancer research meeting (BCRM 2002), 30 June - 3 July 2002, Glasgow, UK.

Cytochrome P450 CYP1B1 is a member of a superfamily of haemoproteins that are central to the oxidative metabolism of a wide variety of endogenous and exogenous compounds. Several of these enzymes have an established role in the metabolic bio-transfor... Read More about Metabolically active cytochrome P450 CYP1B1 in solid tumours: a novel target for chemotherapeutic intervention..