All Outputs (2)

Differential regulation of CYP4Z1 mRNA in human breast cancer cell lines. (2008)
Presentation / Conference
WARASIHA, B., KNOTT, R. and MCFADYEN, M. 2008. Differential regulation of CYP4Z1 mRNA in human breast cancer cell lines. Presented at the 2008 National Cancer Research Institute cancer conference (NCRI 2008), 5-8 October 2008, Birmingham, UK.

CYP4Z1 is a novel cytochrome P450 enzyme that is preferentially expressed in normal breast and neoplastic breast tissue. This poster reported on the results of a study in which an in vitro cell model was used to define the mechanisms regulating CYP4Z... Read More about Differential regulation of CYP4Z1 mRNA in human breast cancer cell lines..

Cytochrome P450 mRNA profile in human breast cancer cell lines. (2008)
Thesis
WARASIHA, B. 2008. Cytochrome P450 mRNA profile in human breast cancer cell lines. Robert Gordon University, PhD thesis.

Cytochrome P450 enzymes (P450s) are involved in cancer development and treatment due to their roles in the oxidative metabolism of various compounds, both endogenous (e.g. oestrogen) and exogenous (e.g. tamoxifen). Intermediate P450 metabolites deriv... Read More about Cytochrome P450 mRNA profile in human breast cancer cell lines..