A genome-wide association study provides evidence of sex-specific involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) with diabetic neuropathic pain.

Meng, Weihua; Deshmukh, Harshal A.; Donnelly, Louise A.; Wellcome Trust Case Control Consortium 2 (WTCCC2); Surrogate Markers For Micro- And Macro-Vascular Hard Endpoints For Innovative Diabetes Tools (SUMMIT) Study Group; Torrance, Nicola; Colhoun, Helen M.; Palmer, Colin N.A.; Smith, Blair H.

doi:10.1016/j.ebiom.2015.08.001

All Outputs (2)

An epidemiological study of neuropathic pain symptoms in Canadian adults. (2015)
Journal Article
VANDENKERKHOF, E.G., MANN, E.G., TORRANCE, N., SMITH, B.H., JOHNSON, A. and GILRON, I. 2016. An epidemiological study of neuropathic pain symptoms in Canadian adults. Pain research and management [online], 2016, article ID 9815750. Available from: https://doi.org/10.1155/2016/9815750

The reported prevalence of neuropathic pain ranges from 6.9% to 10%; however the only Canadian study reported 17.9%. The objective of this study was to describe the epidemiology of neuropathic pain in Canada. A cross-sectional survey was conducted in... Read More about An epidemiological study of neuropathic pain symptoms in Canadian adults..

A genome-wide association study provides evidence of sex-specific involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) with diabetic neuropathic pain. (2015)
Journal Article
MENG, W., DESHMUKH, H.A., DONNELLY, L.A., WELLCOME TRUST CASE CONTROL CONSORTIUM 2 (WTCCC2), SURROGATE MARKERS FOR MICRO- AND MACRO-VASCULAR HARD ENDPOINTS FOR INNOVATIVE DIABETES TOOLS (SUMMIT) STUDY GROUP, TORRANCE, N., COLHOUN, H.M., PALMER, C.N.A. and SMITH, B.H. 2015. A genome-wide association study provides evidence of sex-specific involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) with diabetic neuropathic pain. EBioMedicine [online], 2(10), pages 1386-1393. Available from: https://doi.org/10.1016/j.ebiom.2015.08.001

Neuropathic pain is defined as pain arising as a direct consequence of a lesion or a disease affecting the somatosensory system and it affects around 1 in 4 diabetic patients in the UK. The purpose of this genome-wide association study (GWAS) was to... Read More about A genome-wide association study provides evidence of sex-specific involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) with diabetic neuropathic pain..