All Outputs (113)

Stereoisomeric profiling of chiral pharmaceutically active compounds in wastewaters and the receiving environment: a catchment-scale and a laboratory study. (2019)
Journal Article
CAMACHO-MUÑOZ, D., PETRIE, B., LOPARDO, L., PROCTOR, K., RICE, J., YOUDAN, J., BARDEN, R. and KASPRZYK-HORDON, B. 2019. Stereoisomeric profiling of chiral pharmaceutically active compounds in wastewaters and the receiving environment: a catchment-scale and a laboratory study. Environment international [online], 127, pages 558-572. Available from: https://doi.org/10.1016/j.envint.2019.03.050

Chiral pharmaceutically active compounds (cPACs) are not currently governed by environmental regulation yet are expected to be in the future. As cPACs can exert stereospecific toxicity in the aquatic environment, it is essential to better understand... Read More about Stereoisomeric profiling of chiral pharmaceutically active compounds in wastewaters and the receiving environment: a catchment-scale and a laboratory study..

Characterisation of the effect of day length, and associated differences in dietary intake, on the gut microbiota of Soay sheep. (2019)
Journal Article
THOMAS, N.A., OLVERA-RAMIREZ, A.M., ABECIA, L., ADAM, C.L., EDWARDS, J.E., COX, G.F., FINDLAY, P.A., DESTABLES, E., WOOD, T.A. and MCEWAN, N.R. 2019. Characterisation of the effect of day length, and associated differences in dietary intake, on the gut microbiota of Soay sheep. Archives of microbiology [online], 201(7), pages 889-896. Available from: https://doi.org/10.1007/s00203-019-01652-w

Differences in the rumen bacterial community have been previously reported for Soay sheep housed under different day length conditions. This study extends this previous investigation to other organs of the digestive tract, as well as the analysis of... Read More about Characterisation of the effect of day length, and associated differences in dietary intake, on the gut microbiota of Soay sheep..

Clinical pharmacy practice in the care of chronic kidney disease patients: a systematic review. (2019)
Journal Article
AL RAIISI, F., STEWART, D., FERNANDEZ-LLIMOS, F., SALGADO, T., MOHAMED, M.F. and CUNNINGHAM, S. 2019. Clinical pharmacy practice in the care of chronic kidney disease patients: a systematic review. International journal of clinical pharmacy [online], 41(3), pages 630-666. Available from: https://doi.org/10.1007/s11096-019-00816-4

Background: Clinical pharmacy services have potential to contribute significantly to the multidisciplinary team providing safe, effective and economic care for patients. Given recent practice developments (e.g. polypharmacy reviews and pharmacist pre... Read More about Clinical pharmacy practice in the care of chronic kidney disease patients: a systematic review..

Synthesis of novel vanillin derivatives: novel multi-targeted scaffold ligands against Alzheimer's disease. (2019)
Journal Article
SCIPIONI, M., KAY, G., MEGSON, I.L. and KONG THOO LIN, P. 2019. Synthesis of novel vanillin derivatives: novel multi-targeted scaffold ligands against Alzheimer’s disease. MedChemComm [online], 10(5), pages 764-777. Available from: https://doi.org/10.1039/c9md00048h

Alzheimer’s Disease (AD) is the most common cause of dementia worldwide, normally affecting people aged over 65. Due to the multifactorial nature of this disease, a “multi-target-directed ligands” (MTDLs) approach for the treatment of this illness ha... Read More about Synthesis of novel vanillin derivatives: novel multi-targeted scaffold ligands against Alzheimer's disease..

An exploration of factors influencing health managers' acceptance of eHealth services in the Kingdom of Saudi Arabia. (2019)
Presentation / Conference
ALSHAHRANI, A., STEWART, D. and MACLURE, K. 2019. An exploration of factors influencing health managers' acceptance of eHealth services in the Kingdom of Saudi Arabia. Presented at the 2019 Health services research and pharmacy practice conference (HSRPP 2019), 8-9 April 2019, Birmingham, UK.

Kingdom of Saudi Arabia (KSA) is a country with one of the largest land masses and difficult geographical terrain in the Middle East. The accessibility of advanced health services, especially for people in rural areas, has been considered one of the... Read More about An exploration of factors influencing health managers' acceptance of eHealth services in the Kingdom of Saudi Arabia..

General public awareness and views of community pharmacy in Scotland: the 'first port of call' study. (2019)
Presentation / Conference
MACLURE, K., CRAIG, G., BOYTER, A., MACLURE, A., POWER, A., OSPREY, A., MCGREGOR, A. and STEWART, D. 2019 General public awareness and views of community pharmacy services in Scotland: the 'first port of call' study. Presented at the 2019 Health services research and pharmacy practice conference (HSRPP 2019), 8-9 April 2019, Birmingham, UK.

The recently published ‘Achieving Excellence in Pharmaceutical Care: a Strategy for Scotland’ urges community pharmacy (CP) to make itself the ‘first port of call’ for healthcare advice. The aim of this research is to explore the Scottish general pub... Read More about General public awareness and views of community pharmacy in Scotland: the 'first port of call' study..

An exploration of community pharmacists' views on the need for, type and content of a tool to support engagement with patients who may be homeless. (2019)
Presentation / Conference
MACLURE, K., GIBSON SMITH, K., PAUDYAL, V. and STEWART, D. 2019. An exploration of community pharmacists' views on the need for, type and content of a tool to support engagement with patients who may be homeless. Presented at the 2019 Health services research and pharmacy practice conference (HSRPP 2019), 8-9 April 2019, Birmingham, UK.

Homelessness remains a global public health concern. A prior survey indicated the need for pharmacist training and coverage of the topic of homelessness around minimising impact of medicines use, referring for social support, confidence in broaching... Read More about An exploration of community pharmacists' views on the need for, type and content of a tool to support engagement with patients who may be homeless..

A chronological review of Scotland's policies and strategic priorities for implementation of pharmacy-related technologies. (2019)
Presentation / Conference
MCNELLIS, A., MACLURE, K., STEWART, D. and MCANAW, J. 2019. A chronological review of Scotland's policies and strategic priorities for implementation of pharmacy-related technologies. Presented at the 25th Health services research and pharmacy practice conference (HSRPP 2019): crossing cultural boundaries; optimising communications for future care, 8-9 April 2019, Birmingham, UK.

National strategies across the world have highlighted the need for improving technology in healthcare. This study aims to summarise the goals and intentions of the Scottish Government and evaluate implementation.

Theoretical approaches in the development and evaluation of behaviour change interversions that improve clinicians' antimicrobial prescribing: a systematic review. (2019)
Presentation / Conference
TALKHAN, H., CUNNINGHAM, S., STEWART, D., MCINTOSH, T., AL-HAIL, M., ROUF, P.V.A. and ZIGLAM, H. 2019. Theoretical approaches in the development and evaluation of behaviour change interventions that improve clinicians’ antimicrobial prescribing: a systematic review. Presented at the 2019 Health services research and pharmacy practice conference (HSRPP 2019), 8-9 April 2019, Birmingham, UK.

Antimicrobial resistance (AMR) and its threats have long been recognised. Many countries have developed antimicrobial stewardship programmes with strategies to optimise antimicrobial prescribing, minimise AMR and improve outcomes. There remains a nee... Read More about Theoretical approaches in the development and evaluation of behaviour change interversions that improve clinicians' antimicrobial prescribing: a systematic review..

Genome-guided screening of bacterial isolates to identify potential antibiotic producers. (2019)
Presentation / Conference
AWOLOPE, O.K., O'DRISCOLL, N.H. and LAMB, A. 2019. Genome-guided screening of bacterial isolates to identify potential antibiotic producers. Presented at the 2019 Microbiology Society annual conference, 8-11 April 2019, Belfast, UK.

The urgent need for new antibiotics cannot be overemphasized. Bacterial secondary metabolites remain a relatively untapped source of new therapies. The ability to produce these bioactive compounds is however not universal to all bacterial species. Tw... Read More about Genome-guided screening of bacterial isolates to identify potential antibiotic producers..

Herbal medicinal product use during pregnancy and the postnatal period: a systematic review. (2019)
Journal Article
MUÑOZ BALBONTIN, Y., STEWART, D., SHETTY, A., FITTON, C.A. and MCLAY, J.S. 2019. Herbal medicinal product use during pregnancy and the postnatal period: a systematic review. Obstetrics and gynecology [online], 133(5), pages 920-932. Available from: https://doi.org/10.1097/aog.0000000000003217

To report the incidence and nature of herbal medicinal products’ adverse events and herb–drug interactions used by some pregnant and postnatal women. The Allied and Complementary Medicine Database, the Cumulative Index to Nursing and Allied Health Li... Read More about Herbal medicinal product use during pregnancy and the postnatal period: a systematic review..

Using next generation sequencing to determine diversity of horse intestinal worms: identifying the equine 'nemabiome'. (2019)
Journal Article
MITCHELL, C.J., O'SULLIVAN, C.M., PINLOCHE, E., WILKINSON, T., MORPHEW, R.M. and MCEWAN, N.R. 2019. Using next generation sequencing to determine diversity of horse intestinal worms: identifying the equine 'nemabiome'. Journal of equine science [online], 30(1), pages 1-5. Available from: https://doi.org/10.1294/jes.30.1

Next generation sequencing of DNA from nematode eggs has been utilised to give the first account of the equine ‘nemabiome’. In all equine faecal samples investigated, multiple species of Strongylidae were detected; ranging from 7.5 (SEM 0.79) with 99... Read More about Using next generation sequencing to determine diversity of horse intestinal worms: identifying the equine 'nemabiome'..

Trends in crop reference evapotranspiration and climatological variables across Ceará state: Brazil. (2019)
Journal Article
PAULINO, V.E.N., STUDART, T.M.C., CAMPOS, J.N.B., PESTANA, C.J., LUNA, R.M., ALVES, J.M.B. 2019. Trends in crop reference evapotranspiration and climatological variables across Ceará state: Brazil. Revista Brasileira de meteorologia [online], 34(1), pages 79-88. Available from: https://doi.org/10.1590/0102-7786334017

Irrigation has a substantial share in total world water demand. At the global level, the withdrawal ratio for agriculture is 69 percent. Irrigation is necessary to compensate evapotranspiration (ET) deficit due to insufficient precipitation. Knowing... Read More about Trends in crop reference evapotranspiration and climatological variables across Ceará state: Brazil..

A theoretically based cross-sectional survey on the behaviours and experiences of clinical pharmacists caring for chronic kidney disease patients. (2019)
Presentation / Conference
AL RAIISI, F., STEWART, D., ASHLEY, C., FAHMY, M. and CUNNINGHAM, S. 2019. A theoretically based cross-sectional survey on the behaviours and experiences of clinical pharmacists caring for chronic kidney disease patients. European journal of hospital pharmacy [online], 26(Supplement 1): proceedings of the 24th European Association of Hospital Pharmacists (EAHP) congress 2019: personalised hospital pharmacy: meeting the needs of every patient, 27-29 March 2019, Barcelona, Spain, article number 4CPS-193. Available from: https://doi.org/10.1136/ejhpharm-2019-eahpconf.342

Chronic kidney disease (CKD) is a comorbid condition with high economic burden. Patients need multiple medications and pharmacists provide care that improves outcomes. Al Raiisi et al. recently completed a systematic review showing a paucity of infor... Read More about A theoretically based cross-sectional survey on the behaviours and experiences of clinical pharmacists caring for chronic kidney disease patients..

Acute dietary zinc deficiency in rats exacerbates myocardial ischaemia-reperfusion injury through depletion of glutathione. (2019)
Journal Article
SKENE, K., WALSH, S.K., OKAFOR, O., GODSMAN, N., BARROWS, C., MEIER, P., GORDON, M.J., BEATTIE, J.H. and WAINWRIGHT, C.L. 2019. Acute dietary zinc deficiency in rats exacerbates myocardial ischaemia-reperfusion injury through depletion of glutathione. British journal of nutrition [online], 121(9), pages 961-973. Available from: https://doi.org/10.1017/S0007114519000230

Zinc (Zn) plays an important role in maintaining the anti-oxidant status within the heart, and helps to counter the acute redox stress that occurs during myocardial ischaemia and reperfusion. Individuals with low zinc (Zn) levels are at greater risk... Read More about Acute dietary zinc deficiency in rats exacerbates myocardial ischaemia-reperfusion injury through depletion of glutathione..

DNA repair as a human biomonitoring tool: comet assay approaches. (2019)
Journal Article
AZQUETA, A., LANGIE, S.A.S., BOUTET-ROBINET, E., DUTHIE, S., LADEIRA, C, MØLLER, P., COLLINS, A.R. and GODSCHALK, R.W.L. 2019. DNA repair as a human biomonitoring tool: comet assay approaches. Mutation research/reviews in mutation research [online], 781, pages 71-87. Available from: https://doi.org/10.1016/j.mrrev.2019.03.002

The comet assay offers the opportunity to measure both DNA damage and repair. Various comet assay based methods are available to measure DNA repair activity, but some requirements should be met for their effective use in human biomonitoring studies.... Read More about DNA repair as a human biomonitoring tool: comet assay approaches..

An improved packing equivalent circuit modeling method with the cell-to-cell consistency state evaluation of the internal connected lithium-ion batteries. (2019)
Journal Article
WANG, S.-L., SHI, J.-Y., FERNANDEZ, C., ZOU, C.-Y., BAI, D.-K. and LI, J.-C. 2019. An improved packing equivalent circuit modeling method with the cell-to-cell consistency state evaluation of the internal connected lithium-ion batteries. Energy science and engineering [online], 7(2), pages 546-556. Available from: https://doi.org/10.1002/ese3.294

The existing equivalent modeling methods reported in literature focuses mainly on the battery cells and do not take the packing consistency state into consideration, which exists on the internal connected cells of the lithium-ion battery pack. An imp... Read More about An improved packing equivalent circuit modeling method with the cell-to-cell consistency state evaluation of the internal connected lithium-ion batteries..

Comprehensive medication reviews by ward-based pharmacists in Swedish hospitals: what does the patient have to say? (2019)
Journal Article
KEMPEN, T.G.H., KÄLVEMARK, A., GILLESPIE, U. and STEWART, D. 2020. Comprehensive medication reviews by ward-based pharmacists in Swedish hospitals: what does the patient have to say? Journal of evaluation in clinical practice [online], 26(1), pages 149-157. Available from: https://doi.org/10.1111/jep.13121

Rationale, aims, and objectives: Inappropriate medication prescribing and use amongst older patients is a major patient safety and health care problem. To promote appropriate medication prescribing and use, comprehensive medication reviews (CMRs) by... Read More about Comprehensive medication reviews by ward-based pharmacists in Swedish hospitals: what does the patient have to say?.

An investigation into the molecular mechanisms of hyperbaric oxygen using a human dermal microvascular endothelial cell line and a porcine retinal explant model. (2019)
Thesis
IWUAGWU, B.U. 2019. An investigation into the molecular mechanisms of hyperbaric oxygen using a human dermal microvascular endothelial cell line and a porcine retinal explant model. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

Diabetes is a debilitating metabolic condition with associated vascular complications that are a major cause of morbidity and mortality. Endothelial dysfunction is central to microvascular complications such as diabetic retinopathy (DR) and impaired... Read More about An investigation into the molecular mechanisms of hyperbaric oxygen using a human dermal microvascular endothelial cell line and a porcine retinal explant model..

An exploration of the medication related experiences of community dwelling adults with learning disabilities. (2019)
Thesis
MACLEOD, J. 2019. An exploration of the medication related experiences of community dwelling adults with learning disabilities. Robert Gordon University [online], DPP thesis. Available from: https://openair.rgu.ac.uk

The purpose of this study was to explore the medication related experiences of community dwelling adults with learning disabilities (LD). A narrative review was undertaken and found that current literature focused on measuring the prevalence of parti... Read More about An exploration of the medication related experiences of community dwelling adults with learning disabilities..