Skip to main content

Research Repository

Advanced Search

Outputs (71)

High structural diversity of aeruginosins in bloom-forming cyanobacteria of the genus Planktothrix as a consequence of multiple recombination events. (2023)
Journal Article
ENTFELLNER, E., BAUMANN, K.B.L., EDWARDS, C. and KURMAYER, R. 2023. High structural diversity of aeruginosins in bloom-forming cyanobacteria of the genus Planktothrix as a consequence of multiple recombination events. Marine drugs [online], 21(12), article number 638. Available from: https://doi.org/10.3390/md21120638

Many compounds produced by cyanobacteria act as serine protease inhibitors, such as the tetrapeptides aeruginosins (Aer), which are found widely distributed. The structural diversity of Aer is intriguingly high. However, the genetic basis of this rem... Read More about High structural diversity of aeruginosins in bloom-forming cyanobacteria of the genus Planktothrix as a consequence of multiple recombination events..

High structural diversity of aeruginosins in bloom-forming cyanobacteria of the genus Planktothrix as a consequence of multiple recombination events. [Dataset] (2023)
Dataset
ENTFELLNER, E., BAUMANN, K.B.L., EDWARDS, C. and KURMAYER, R. 2023. High structural diversity of aeruginosins in bloom-forming cyanobacteria of the genus Planktothrix as a consequence of multiple recombination events. [Dataset]. Marine drugs [online], 21(12), article number 638. Available from: https://www.mdpi.com/article/10.3390/md21120638/s1

Many compounds produced by cyanobacteria act as serine protease inhibitors, such as the tetrapeptides aeruginosins (Aer), which are found widely distributed. The structural diversity of Aer is intriguingly high. However, the genetic basis of this rem... Read More about High structural diversity of aeruginosins in bloom-forming cyanobacteria of the genus Planktothrix as a consequence of multiple recombination events. [Dataset].

Nature-based solution to eliminate cyanotoxins in water using biologically enhanced biochar. (2023)
Journal Article
MOORE, J., JAYAKUMAR, A., SOLDATOU, S., MAŠEK, O., LAWTON, L.A. and EDWARDS, C. 2023. Nature-based solution to eliminate cyanotoxins in water using biologically enhanced biochar. Environmental science and technology [online], 57(43), pages 16372-16385. Available from: https://doi.org/10.1021/acs.est.3c05298

Climate change and high eutrophication levels of freshwater sources are increasing the occurrence and intensity of toxic cyanobacterial blooms in drinking water supplies. Conventional water treatment struggles to eliminate cyanobacteria/cyanotoxins a... Read More about Nature-based solution to eliminate cyanotoxins in water using biologically enhanced biochar..

Transformation products of microcystin-RR with reactive species produced by radiolysis of water. (2023)
Conference Proceeding
ILIAKOPOULOUS, S., TRIANTIS, T., ANTONOPOULOU, M., EDWARDS, C., LINDA, L., KISKIA, A. and KALOUDIS, T. 2023. Transformation products of microcystin-RR with reactive species produced by radiolysis of water. In Proceedings of the 18th International conference on environmental science and technology 2023 (CEST2023), 30 August - 2 September 2023, Athens, Greece. Athens: COSMOS SA [online], paper ID cest2023_00012. Available from: https://doi.org/10.30955/gnc2023.00012

Microcystins (MCs) are potent cyclic-peptide toxins produced by cyanobacteria during freshwater bloom episodes. They can severely impact drinking water supplies and recreational waters. More than 300 MCs are known today, which are toxic, mainly by in... Read More about Transformation products of microcystin-RR with reactive species produced by radiolysis of water..

Bio-based sustainable polymers and materials: from processing to biodegradation. (2023)
Journal Article
OKOLIE, O., KUMAR, A., EDWARDS, C., LAWTON, L.A., OKE, A., MCDONALD, S., THAKUR, V.K. and NJUGUNA, J. 2023. Bio-based sustainable polymers and materials: from processing to biodegradation. Journal of composites science [online], 7(6), article 213. Available from: https://doi.org/10.3390/jcs7060213

In the life cycle of a material, there will be either chemical or physical change due to varying environmental factors such as biological activity, light, heat, moisture, and chemical conditions. This process leads to polymer property change as perta... Read More about Bio-based sustainable polymers and materials: from processing to biodegradation..

Systematic evaluation of pyrolysis processes and biochar quality in the operation of low-cost flame curtain pyrolysis kiln for sustainable biochar production. (2023)
Journal Article
JAYAKUMAR, A., MORRISSET, D., KOUTSOMARKOS, V., WURZER, C., HADDEN, R.M., LAWTON, L., EDWARDS, C. and MAŠEK, O. 2023. Systematic evaluation of pyrolysis processes and biochar quality in the operation of low-cost flame curtain pyrolysis kiln for sustainable biochar production. Current research in environmental sustainability [online], 5, article 100213. Available from: https://doi.org/10.1016/j.crsust.2023.100213

Low-cost pyrolysis units such as flame curtain pyrolysis kilns are gaining popularity for biochar production. However, the processes that govern the working of such units are not well understood. Here, emissions, temperatures and mass loss are monito... Read More about Systematic evaluation of pyrolysis processes and biochar quality in the operation of low-cost flame curtain pyrolysis kiln for sustainable biochar production..

A feasibility study into the production of a mussel matrix reference material for the cyanobacterial toxins microcystins and nodularins. (2022)
Journal Article
TURNER, A.D., BEACH, D.G., FOSS, A., SAMDAL, I.A., LØVBERG, K.L.E., WAACK, J., EDWARDS, C., LAWTON, L.A., DEAN, K.J., MASKREY, B.H. and LEWIS, A.M. 2023. A feasibility study into the production of a mussel matrix reference material for the cyanobacterial toxins microcystins and nodularins. Toxins [online], 15(1), article 27. Available from: https://doi.org/10.3390/toxins15010027

Microcystins and nodularins, produced naturally by certain species of cyanobacteria, have been found to accumulate in aquatic foodstuffs such as fish and shellfish, resulting in a risk to the health of the seafood consumer. Monitoring of toxins in su... Read More about A feasibility study into the production of a mussel matrix reference material for the cyanobacterial toxins microcystins and nodularins..

Suppressing cyanobacterial dominance by UV-LED TiO2-photocatalysis in a drinking water reservoir: a mesocosm study. (2022)
Journal Article
PESTANA, C.J., SANTOS, A.A., CAPELO-NETO, J. et al. 2022. Suppressing cyanobacterial dominance by UV-LED TiO2-photocatalysis in a drinking water reservoir: a mesocosm study. Water research [online], 226, article 119299. Available from: https://doi.org/10.1016/j.watres.2022.119299

Cyanobacteria and their toxic secondary metabolites present challenges for water treatment globally. In this study we have assessed TiO2 immobilized onto recycled foamed glass beads by a facile calcination method, combined in treatment units with 365... Read More about Suppressing cyanobacterial dominance by UV-LED TiO2-photocatalysis in a drinking water reservoir: a mesocosm study..

Solar-driven semi-conductor photocatalytic water treatment (TiO2, g-C3N4, and TiO2+g-C3N4) of cyanotoxins: proof-of-concept study with microcystin-LR. (2022)
Journal Article
PESTANA, C.J., HUI, J., CAMACHO-MUÑOZ, D., EDWARDS, C., ROBERTSON, P.K.J., IRVINE, J.T.S. and LAWTON, L.A. 2022. Solar-driven semi-conductor photocatalytic water treatment (TiO2, g-C3N4, and TiO2+g-C3N4) of cyanotoxins: proof-of-concept study with microcystin-LR. Chemosphere [online], 310, article 136828. Available from: https://doi.org/10.1016/j.chemosphere.2022.136828

Cyanobacteria and their toxins are a threat to drinking water safety as increasingly cyanobacterial blooms (mass occurrences) occur in lakes and reservoirs all over the world. Photocatalytic removal of cyanotoxins by solar light active catalysts is a... Read More about Solar-driven semi-conductor photocatalytic water treatment (TiO2, g-C3N4, and TiO2+g-C3N4) of cyanotoxins: proof-of-concept study with microcystin-LR..

Water taste and odor (T&O): challenges, gaps and solutions from a perspective of the WaterTOP network. (2022)
Journal Article
AKCAALAN, R., DEVESA-GARRIGA, R., DIETRICH, A., et al. 2022. Water taste and odor (T&O): challenges, gaps and solutions from a perspective of the WaterTOP network. Chemical engineering journal advances [online], 12, article 100409. Available from: https://doi.org/10.1016/j.ceja.2022.100409

Aesthetic aspects of drinking water, such as Taste and Odor (T&O), have significant effects on consumer perceptions and acceptability. Solving unpleasant water T&O episodes in water supplies is challenging, since it requires experti... Read More about Water taste and odor (T&O): challenges, gaps and solutions from a perspective of the WaterTOP network..

A paradigm-shift in water treatment: in-reservoir UV-LED-driven TiO2 photocatalysis for the removal of cyanobacteria: a mesocosm study. (2022)
Presentation / Conference
PESTANA, C.J., CAPELO-NETO, J., HUI, J., ROBERTSON, P.K.J., OLIVEIRA, S., ROGERS, R., SANTOS, A., AZEVEDO, S.M.F.O., EDWARDS, C., IRVINE, J.T.S. and LAWTON, L.A. 2022. A paradigm-shift in water treatment: in-reservoir UV-LED-driven TiO2 photocatalysis for the removal of cyanobacteria: a mesocosm study. Presented at the 12th International conference on toxic cyanobacteria (ICTC 2022), 22-27 May 2022, Toledo, USA.

Potentially harmful cyanobacteria challenge potable water treatment globally, with high biomass events, and dissolved toxic and nuisance metabolites. Retrofitting existing water treatment infrastructure is often impractical (if not impossible) and of... Read More about A paradigm-shift in water treatment: in-reservoir UV-LED-driven TiO2 photocatalysis for the removal of cyanobacteria: a mesocosm study..

An evaluation of feedstocks for sustainable energy and circular economy practices in a small island community. (2022)
Journal Article
REYNOLDS, J., KENNEDY, R., ICHAPKA, M., AGARWAL, A., OKE, A., COX, E., EDWARDS, C. and NJUGUNA, J. 2022. An evaluation of feedstocks for sustainable energy and circular economy practices in a small island community. Renewable and sustainable energy reviews [online], 161, article 112360. Available from: https://doi.org/10.1016/j.rser.2022.112360

Maximising the use of anaerobic digestion to generate power from waste feedstocks is becoming a practical way to use waste contributing to the transition from a linear to a circular economy and reducing the carbon footprint. In addition to harnessing... Read More about An evaluation of feedstocks for sustainable energy and circular economy practices in a small island community..

Adsorption of cyanotoxins on polypropylene and polyethylene terephthalate: microplastics as vector of eight microcystin analogues. (2022)
Journal Article
MOURA, D.S., PESTANA, C.J., MOFFAT, C.F., HUI, J., IRVINE, J.T.S., EDWARDS, C. and LAWTON, L.A. 2022. Adsorption of cyanotoxins on polypropylene and polyethylene terephthalate: microplastics as vector of eight microcystin analogues. Environmental pollution [online], 303, article 119135. Available from: https://doi.org/10.1016/j.envpol.2022.119135

Plastics are utilised globally but are of environmental concern due to their persistence. The global presence of microplastics (particles

Biological activity and stability of aeruginosamides from cyanobacteria. (2022)
Journal Article
CEGLOWSKA, M., KWIECIEŃ, P., SZUBERT, K., BRZUZAN, P., FLORCZYK, M., EDWARDS, C., KOSAKOWSKA, A. and MAZUR-MARZEC, H. 2022. Biological activity and stability of aeruginosamides from cyanobacteria. Marine drugs [online], 20(2): pharmaceutical potential of marine microorganisms, article 93. Available from: https://doi.org/10.3390/md20020093

Aeruginosamides (AEGs) are classified as cyanobactins, ribosomally synthesized peptides with post-translational modifications. They have been identified in cyanobacteria of genera Microcystis, Oscillatoria, and Limnoraphis. In this work, the new data... Read More about Biological activity and stability of aeruginosamides from cyanobacteria..

Recoverable resources from pot ale and spent wash from Scotch whisky production. (2021)
Journal Article
EDWARDS, C., MCNERNEY, C.C., LAWTON, L.A., PALMER, J., MACGREGOR, K., JACK, F., COCKBURN, P., PLUMMER, A., LOVEGROVE, A. and WOOD, A. 2022. Recoverable resources from pot ale and spent wash from Scotch whisky production. Resources, conservation and recycling [online], 179, article number 106114. Available from: https://doi.org/10.1016/j.resconrec.2021.106114

Scotch Whisky is an important global commodity which generates extensive co-product known as pot ale or spent wash (> 10 L co-product per L whisky). Whilst this is often used as fertiliser or animal feed, a proportion requires disposal resulting in c... Read More about Recoverable resources from pot ale and spent wash from Scotch whisky production..

Potentially poisonous plastic particles: microplastics as a vector for cyanobacterial toxins microcystin-LR and microcystin-LF. (2021)
Journal Article
PESTANA, C.J., MOURA, D.S., CAPELO-NETO, J., EDWARDS, C., DREISBACH, D., SPENGLER, B. and LAWTON, L.A. 2021. Potentially poisonous plastic particles: microplastics as a vector for cyanobacterial toxins microcystin-LR and microcystin-LF. Environmental science and technology [online], 55(23), pages 15940-15949. Available from: https://doi.org/10.1021/acs.est.1c05796

The potential of microplastics to act as a vector for micropollutants of natural or anthropogenic origin is of rising concern. Cyanobacterial toxins, including microcystins, are harmful to humans and wildlife. In this study, we demonstrate for the fi... Read More about Potentially poisonous plastic particles: microplastics as a vector for cyanobacterial toxins microcystin-LR and microcystin-LF..

Stratification strength and light climate explain variation in chlorophyll α at the continental scale in a European multilake survey in a heatwave summer. (2021)
Journal Article
DONIS, D., MANTZOUKI, E., MCGINNIS, D.F. et al. 2021. Stratification strength and light climate explain variation in chlorophyll a at the continental scale in a European multilake survey in a heatwave summer. Limnology and oceanography [online], 66(12), pages 4314-4333. Available from: https://doi.org/10.1002/lno.11963

To determine the drivers of phytoplankton biomass, we collected standardized morphometric, physical, and biological data in 230 lakes across the Mediterranean, Continental, and Boreal climatic zones of the European continent. Multilinear regression m... Read More about Stratification strength and light climate explain variation in chlorophyll α at the continental scale in a European multilake survey in a heatwave summer..

Nostocyclopeptides as new inhibitors of 20s proteasome. (2021)
Journal Article
FIDOR, A., CEKAŁA, K., WIECZERZAK, E., CEGŁOWSKA, M., KASPRZYKOWSKI, F., EDWARDS, C. and MAZUR-MARZEC, H. 2021. Nostocyclopeptides as new inhibitors of 20S proteasome. Biomolecules [online], 11(10), article 1483. Available from: https://doi.org/10.3390/biom11101483

Nostocyclopeptides (Ncps) are a small class of bioactive nonribosomal peptides produced solely by cyanobacteria of the genus Nostoc. In the current work, six Ncps were isolated from Nostoc edaphicum strain CCNP1411. The bioactivity of these compounds... Read More about Nostocyclopeptides as new inhibitors of 20s proteasome..

Comparison of UV-A photolytic and UV/TiO2 photocatalytic effects on Microcystis aeruginosa PCC7813 and four microcystin analogues: a pilot scale study. [Dataset] (2021)
Dataset
MENEZES, I., CAPELO-NETO, J., PESTANA, C.J., CLEMENTE, A., HUI, J., IRVINE, J.T.S., GUNARATNE, H.Q.N., ROBERTSON, P.K.J., EDWARDS, C., GILLANDERS, R.N., TURNBULL, G.A. and LAWTON, L.A. 2021. Comparison of UV-A photolytic and UV/TiO2 photocatalytic effects on Microcystis aeruginosa PCC7813 and four microcystin analogues: a pilot scale study. [Dataset]. Journal of environmental management [online], 298, article 113519. Available from: https://www.sciencedirect.com/science/article/pii/S0301479721015814#appsec1

Cyanobacterial blooms in freshwater reservoirs represent a threat to human and animal health because of the potential release of a wide variety of harmful metabolites, known collectively as cyanotoxins. Microcystins (MCs) are one of the most commonly... Read More about Comparison of UV-A photolytic and UV/TiO2 photocatalytic effects on Microcystis aeruginosa PCC7813 and four microcystin analogues: a pilot scale study. [Dataset].

Comparison of UV-A photolytic and UV/TiO2 photocatalytic effects on Microcystis aeruginosa PCC7813 and four microcystin analogues: a pilot scale study. (2021)
Journal Article
MENEZES, I., CAPELO-NETO, J., PESTANA, C.J., CLEMENTE, A., HUI, J., IRVINE, J.T.S., GUNARATNE, H.Q.N., ROBERTSON, P.K.J., EDWARDS, C., GILLANDERS, R.N., TURNBULL, G.A. and LAWTON, L.A. 2021. Comparison of UV-A photolytic and UV/TiO2 photocatalytic effects on Microcystis aeruginosa PCC7813 and four microcystin analogues: a pilot scale study. Journal of environmental management [online], 298, article 113519. Available from: https://doi.org/10.1016/j.jenvman.2021.113519

To date, the high cost of supplying UV irradiation has prevented the widespread application of UV photolysis and titanium dioxide based photocatalysis in removing undesirable organics in the water treatment sector. To overcome this problem, the use o... Read More about Comparison of UV-A photolytic and UV/TiO2 photocatalytic effects on Microcystis aeruginosa PCC7813 and four microcystin analogues: a pilot scale study..

New directions and challenges in engineering biologically-enhanced biochar for biological water treatment. (2021)
Journal Article
JAYAKUMAR, A., WURZER, C., SOLDATOU, S., EDWARDS, C., LAWTON, L.A. and MAŠEK, O. 2021. New directions and challenges in engineering biologically-enhanced biochar for biological water treatment. Science of the total environment [online], 796, article number 148977. Available from: https://doi.org/10.1016/j.scitotenv.2021.148977

Cost-effective, efficient, and sustainable water treatment solutions utilising existing materials and technology will make it easier for low and middle-income countries to adopt them, improving public health. The ability of biochar to mediate and sup... Read More about New directions and challenges in engineering biologically-enhanced biochar for biological water treatment..

High value phycotoxins from the dinoflagellate Prorocentrum. (2021)
Journal Article
CAMACHO-MUÑOZ, D., PRAPTIWI, R.A., LAWTON, L.A. and EDWARDS, C. 2021. High value phycotoxins from the dinoflagellate Prorocentrum. Frontiers in marine science [online], 8, article number 638739. Available from: https://doi.org/10.3389/fmars.2021.638739

Marine dinoflagellates produce chemically diverse compounds, with a wide range of biological activity (antimicrobial, anticancer, treatment of neurodegenerative disease along with use as biomedical research tools). Chemical diversity is highlighted b... Read More about High value phycotoxins from the dinoflagellate Prorocentrum..

A new tool for faster construction of marine biotechnology collaborative networks. (2021)
Journal Article
ROTTER, A., GAUDÊNCIO, S.P., KLUN, K., MACHER, J.-N., THOMAS, O.P., DENIZ, I., EDWARDS, C., GRIGALIONYTE-BEMBIČ, E., LJUBEŠIĆ, Z., ROBBENS, J., VARESE, G.C. and VASQUEZ, M.I. 2021. A new tool for faster construction of marine biotechnology collaborative networks. Frontiers in marine science [online], 8, article 685164. Available from: https://doi.org/10.3389/fmars.2021.685164

The increasing and rapid development in technologies, infrastructures, computational power, data availability and information flow has enabled rapid scientific advances. These entail transdisciplinary collaborations that maximize sharing of data and... Read More about A new tool for faster construction of marine biotechnology collaborative networks..

Degradation of multiple peptides by microcystin-degrader Paucibacter toxinivorans (2C20). [Dataset] (2021)
Dataset
SANTOS, A.A., SOLDATOU, S., FREITAS DE MAGALHÃES, V., AZEVEDO, S.M.F.O., CAMACHO-MUÑOZ, D., LAWTON, L. A. and EDWARDS, C. 2021. Degradation of multiple peptides by microcystin-degrader Paucibacter toxinivorans (2C20). [Dataset]. Toxins [online], 13(4): cyanobacterial toxins: their occurrence, detection and removal, article 265. Available from: https://www.mdpi.com/2072-6651/13/4/265/s1

The presence of harmful algal bloom in many reservoirs around the world, alongside the lack of sanitation law/ordinance regarding cyanotoxin monitoring (particularly in developing countries), create a scenario in which the local population could pote... Read More about Degradation of multiple peptides by microcystin-degrader Paucibacter toxinivorans (2C20). [Dataset].

Degradation of multiple peptides by microcystin-degrader Paucibacter toxinivorans (2C20). (2021)
Journal Article
SANTOS, A.A., SOLDATOU, S., FREITAS DE MAGALHÃES, V., AZEVEDO, S.M.F.O., CAMACHO-MUÑOZ, D., LAWTON, L. A. and EDWARDS, C. 2021. Degradation of multiple peptides by microcystin-degrader Paucibacter toxinivorans (2C20). Toxins [online], 13(4): cyanobacterial toxins: their occurrence, detection and removal, article 265. Available from: https://doi.org/10.3390/toxins13040265

Since conventional drinking water treatments applied in different countries are inefficient at eliminating potentially toxic cyanobacterial peptides, a number of bacteria have been studied as an alternative to biological filters for the removal of mi... Read More about Degradation of multiple peptides by microcystin-degrader Paucibacter toxinivorans (2C20)..

Current trends and challenges for rapid SMART diagnostics at point-of-site testing for marine toxins. (2021)
Journal Article
DILLON, M., ZACZEK-MOCZYDLOWSKA, M.A., EDWARDS, C., TURNER, A.D., MILLER, P.I., MOORE, H., MCKINNEY, A., LAWTON, L. and CAMPBELL, K. 2021. Current trends and challenges for rapid SMART diagnostics at point-of-site testing for marine toxins. Sensors [online], 21(7), article 2499. Available from: https://doi.org/10.3390/s21072499

In the past twenty years marine biotoxin analysis in routine regulatory monitoring has advanced significantly in Europe (EU) and other regions from the use of the mouse bioassay (MBA) towards the high-end analytical techniques such as high-performanc... Read More about Current trends and challenges for rapid SMART diagnostics at point-of-site testing for marine toxins..

Effect of hydrogen peroxide on natural phytoplankton and bacterioplankton in a drinking water reservoir: mesocosm-scale study. (2021)
Journal Article
SANTOS, A.A., GUEDES, D.O., BARROS, M.U.G., OLIVEIRA, S., PACHECO, A.B.F., AZEVEDO, S.M.F.O., MAGALHÃES, V.F., PESTANA, C.J., EDWARDS, C., LAWTON, L.A. and CAPELO-NETO, J. 2021. Effect of hydrogen peroxide on natural phytoplankton and bacterioplankton in a drinking water reservoir: mesocosm-scale study. Water research [online], 197, article 117069. Available from: https://doi.org/10.1016/j.watres.2021.117069

Cyanobacterial blooms are increasingly reported worldwide, presenting a challenge to water treatment plants and concerning risks to human health and aquatic ecosystems. Advanced oxidative processes comprise efficient and safe methods for water treatm... Read More about Effect of hydrogen peroxide on natural phytoplankton and bacterioplankton in a drinking water reservoir: mesocosm-scale study..

The essentials of marine biotechnology. (2021)
Journal Article
ROTTER, A., BARBIER, M., BERTONI, F. et al. 2021. The essentials of marine biotechnology. Frontiers in marine science [online], 8, article 629629. Available from: https://doi.org/10.3389/fmars.2021.629629

Coastal countries have traditionally relied on the existing marine resources (e.g., fishing, food, transport, recreation, and tourism) as well as tried to support new economic endeavors (ocean energy, desalination for water supply, and seabed mining)... Read More about The essentials of marine biotechnology..

Cell free Microcystis aeruginosa spent medium affects Daphnia magna survival and stress response. (2021)
Journal Article
BOJADZIJA SAVIC, G., COLINET, H., BORMANS, M., EDWARDS, C., LAWTON, L.A., BRIAND, E. and WIEGAND, C. 2021. Cell free Microcystis aeruginosa spent medium affects Daphnia magna survival and stress response. Toxicon [online], 195, pages 37-47. Available from: https://doi.org/10.1016/j.toxicon.2021.03.009

Primary consumers in freshwater ecosystems, such as the zooplankton organism Daphnia magna, are highly affected by cyanobacteria, both as they may use it as a food source but also by cyanobacterial metabolites present in the water. Here, we investiga... Read More about Cell free Microcystis aeruginosa spent medium affects Daphnia magna survival and stress response..

Rapid analytical methods for the microalgal and cyanobacterial biorefinery: application on strains of industrial importance. (2021)
Journal Article
PALMER, J.S., LAWTON, L.A., KINDT, R. and EDWARDS, C. 2021. Rapid analytical methods for the microalgal and cyanobacterial biorefinery: application on strains of industrial importance. MicrobiologyOpen [online], 10(1), article number e1156. Available from: https://doi.org/10.1002/mbo3.1156

To realise the potential of microalgae in the biorefinery context, exploitation of multiple products is necessary for profitability and for bioproduct valorisation. Appropriate analytical tools are required for growth optimisation, culture monitoring... Read More about Rapid analytical methods for the microalgal and cyanobacterial biorefinery: application on strains of industrial importance..

Rapid uptake and slow depuration: health risks following cyanotoxin accumulation in mussels? (2020)
Journal Article
CAMACHO-MUÑOZ, D., WAACK, J., TURNER, A.D., LEWIS, A.M., LAWTON, L.A. and EDWARDS, C. 2021. Rapid uptake and slow depuration: health risks following cyanotoxin accumulation in mussels? Environmental pollution [online], 271, article ID 116400. Available from: https://doi.org/10.1016/j.envpol.2020.116400

Freshwater cyanobacteria produce highly toxic secondary metabolites, which can be transported downstream by rivers and waterways into the sea. Estuarine and coastal aquaculture sites exposed to toxic cyanobacteria raise concerns that shellfish may ac... Read More about Rapid uptake and slow depuration: health risks following cyanotoxin accumulation in mussels?.

Anatoxin-a degradation by using titanium dioxide. (2020)
Journal Article
KAMINSKI, A., EDWARDS, C., CHRAPUSTA-SREBRNY, E. and LAWTON, L.A. 2021. Anatoxin-a degradation by using titanium dioxide. Science of the total environment [online], 756, article ID 143590. Available from: https://doi.org/10.1016/j.scitotenv.2020.143590

Advanced oxidation processes, such as using titanium dioxide (TiO2) photocatalysis, are being developed to reduce or eliminate the toxicity of treated water. In this study, the removal of purified anatoxin-a (ANTX-a), live Dolichospermum flos-aquae c... Read More about Anatoxin-a degradation by using titanium dioxide..

Oxidative stress in the cyanobacterium microcystis aeruginosa PCC 7813: comparison of different analytical cell stress detection assays. (2020)
Journal Article
MENEZES, I., MAXWELL-MCQUEENEY, D., CAPELO-NETO, J., PESTANA, C.J., EDWARDS, C. and LAWTON, L.A. 2021. Oxidative stress in the cyanobacterium Microcystis aeruginosa PCC 7813: comparison of different analytical cell stress detection assays. Chemosphere [online], 269, article ID 128766. Available from: https://doi.org/10.1016/j.chemosphere.2020.128766

Cyanobacterial blooms are observed when high cell densities occur and are often dangerous to human and animal health due to the presence of cyanotoxins. Conventional drinking water treatment technology struggles to efficiently remove cyanobacterial c... Read More about Oxidative stress in the cyanobacterium microcystis aeruginosa PCC 7813: comparison of different analytical cell stress detection assays..

Graphitic-C3N4 coated floating glass beads for photocatalytic destruction of synthetic and natural organic compounds in water under UV light. (2020)
Journal Article
HUI, J., PESTANA, C.J., CAUX, M., GUNARATNE, H.Q.N., EDWARDS, C., ROBERTSON, P.K.J., LAWTON, L.A. and IRVINE, J.T.S. 2020. Graphitic-C3N4 coated floating glass beads for photocatalytic destruction of synthetic and natural organic compounds in water under UV light. Journal of photochemistry and photobiology A: chemistry [online], 405, article ID 112935. Available from: https://doi.org/10.1016/j.jphotochem.2020.112935

Many drinking water reservoirs can contain organic pollutants such as artificial synthesized dye and drugs. On the other hand, some naturally occurring microorganisms such as cyanobacteria, are capable of producing toxic secondary metabolites (cyanot... Read More about Graphitic-C3N4 coated floating glass beads for photocatalytic destruction of synthetic and natural organic compounds in water under UV light..

Degradation of microcystin-LR and cylindrospermopsin by continuous flow UV-A photocatalysis over immobilised TiO2. (2020)
Journal Article
CAMACHO-MUÑOZ, D., FERVERS, A.-S., PESTANA, C.J., EDWARDS, C. and LAWTON, L.A. 2020. Degradation of microcystin-LR and cylindrospermopsin by continuous flow UV-A photocatalysis over immobilised TiO2. Journal of environmental management [online], 276, article ID 111368. Available from: https://doi.org/10.1016/j.jenvman.2020.111368

The increasing presence of freshwater toxins have brought new challenges to preserve water quality due to their potential impact on the environment and human health. Two commonly occurring cyanotoxins, microcystin-LR and cylindrospermopsin, with diff... Read More about Degradation of microcystin-LR and cylindrospermopsin by continuous flow UV-A photocatalysis over immobilised TiO2..

Photocatalytic removal of the cyanobacterium Microcystis aeruginosa PCC7813 and four microcystins by TiO2 coated porous glass beads with UV-LED irradiation. (2020)
Journal Article
PESTANA, C.J., PORTELA NORONHA, J., HUI, J., EDWARDS, C., GUNARATNE, H.Q.N., IRVINE, J.T.S., ROBERTSON, P.K.J., CAPELO-NETO, J. and LAWTON, L.A. 2020. Photocatalytic removal of the cyanobacterium Microcystis aeruginosa PCC7813 and four microcystins by TiO2 coated porous glass beads with UV-LED irradiation. Science of the total environment [online], 745, article number 141154. Available from: https://doi.org/10.1016/j.scitotenv.2020.141154

Cyanobacteria and their toxic secondary metabolites are a challenge in water treatment due to increased biomass and dissolved metabolites in the raw water. Retrofitting existing water treatment infrastructure is prohibitively expensive or unfeasible,... Read More about Photocatalytic removal of the cyanobacterium Microcystis aeruginosa PCC7813 and four microcystins by TiO2 coated porous glass beads with UV-LED irradiation..

Exploitation of underused Streptomyces through a combined metabolomics-genomics workflow to enhance natural product diversity. (2020)
Thesis
BURNS, J. 2020. Exploitation of underused streptomyces through a combined metabolomics-genomics workflow to enhance natural product diversity. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

The genus Streptomyces is the source of approximately two-thirds of all clinically-used antibiotics. Despite being the source of so many specialised metabolites, genomic analysis indicates that most Streptomyces strains have the potential to produce... Read More about Exploitation of underused Streptomyces through a combined metabolomics-genomics workflow to enhance natural product diversity..

Degradation of okadaic acid in seawater by UV/TiO2 photocatalysis: proof of concept. (2020)
Journal Article
CAMACHO-MUÑOZ, D., LAWTON, L.A. and EDWARDS, C. 2020. Degradation of okadaic acid in seawater by UV/TiO2 photocatalysis: proof of concept. Science of the total environment [online], 733, article ID 139346. Available from: https://doi.org/10.1016/j.scitotenv.2020.139346

The consumption of contaminated shellfish with marine toxins causes adverse socioeconomical, environmental and health impacts. The marine toxin okadaic acid (OA) provokes diarrhetic shellfish poisoning (DSP) syndrome characterized by severe gastroint... Read More about Degradation of okadaic acid in seawater by UV/TiO2 photocatalysis: proof of concept..

Cross talk: two way allelopathic interactions between toxic Microcystis and Daphnia. (2020)
Journal Article
BOJADZIJA SAVIC, G., BORMANS, M., EDWARDS, C., LAWTON, L., BRIAND, E. and WIEGAND, C. 2020. Cross talk: two way allelopathic interactions between toxic Microcystis and Daphnia. Harmful algae [online], 94, article ID 101803. Available from: https://doi.org/10.1016/j.hal.2020.101803

Due to eutrophication, freshwater ecosystems frequently experience cyanobacterial blooms, many of which produce bioactive metabolites that can affect vertebrates and invertebrates life traits. Zooplankton are able to develop tolerance as a physiologi... Read More about Cross talk: two way allelopathic interactions between toxic Microcystis and Daphnia..

'All in one' photo-reactor pod containing TiO2 coated glass beads and LEDs for continuous photocatalytic destruction of cyanotoxins in water. (2020)
Journal Article
GUNARATNE, H.Q.N., PESTANA, C.J., SKILLEN, N., HUI, J., SARAVANAN, S., EDWARDS, C., IRVINE, J.T.S., ROBERTSON, P.K.J. and LAWTON, L.A. 2020. ‘All in one’ photo-reactor pod containing TiO2 coated glass beads and LEDs for continuous photocatalytic destruction of cyanotoxins in water. Environmental science: water research and technology [online], 6(4), pages 945-950. Available from: https://doi.org/10.1039/c9ew00711c

Blooms of blue-green algae (cyanobacteria) in water reservoirs frequently produce highly toxic secondary metabolites including microcystins which have resulted in both human and animal fatalities. To tackle this global problem, we present here a viab... Read More about 'All in one' photo-reactor pod containing TiO2 coated glass beads and LEDs for continuous photocatalytic destruction of cyanotoxins in water..

Phosphate and nitrate supplementations to evaluate the effect on cell biomass, intra and extracellular nodularin and nodulopeptin 901 produced by the cyanobacterium Nodularia spumigena KAC 66. (2019)
Journal Article
HAMEED, S., LAWTON, L.A. and EDWARDS, C. 2020. Phosphate and nitrate supplementations to evaluate the effect on cell biomass, intra and extracellular nodularin and nodulopeptin 901 produced by the cyanobacterium Nodularia spumigena KAC 66. Journal of applied phycology [online], 32(2), pages 937-950. Available from: https://doi.org/10.1007/s10811-019-02008-z

Blooms of the cyanobacterium Nodularia spumigena occur regularly in the Baltic Sea typically producing a wide range of bioactive peptides including the hepatotoxin nodularin (NOD), spumigins, anabaenopeptins and nodulopeptins (molecular weights: 917,... Read More about Phosphate and nitrate supplementations to evaluate the effect on cell biomass, intra and extracellular nodularin and nodulopeptin 901 produced by the cyanobacterium Nodularia spumigena KAC 66..

Daphnia magna exudates impact physiological and metabolic changes in microcystis aeruginosa. (2019)
Journal Article
SAVIC, G.B., EDWARDS, C., BRIAND, E., LAWTON, L., WIEGAND, C. and BORMANS, M. 2019. Daphnia magna exudates impact physiological and metabolic changes in microcystis aeruginosa. Toxins [online], 11(7), article number 421. Available from: https://doi.org/10.3390/toxins11070421

While the intracellular function of many toxic and bioactive cyanobacterial metabolites is not yet known, microcystins have been suggested to have a protective role in the cyanobacterial metabolism, giving advantage to toxic over nontoxic strains und... Read More about Daphnia magna exudates impact physiological and metabolic changes in microcystis aeruginosa..

Exploring the potential resource recovery from pot ale utilising microalgae and novel LED photobioreactors. (2019)
Thesis
MCNERNEY, C.C. 2019. Exploring the potential resource recovery from pot ale utilising microalgae and novel LED photobioreactors. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

Pot ale is a protein-rich, high-carbon and acidic (pH 3.5) by-product of the whisky industry. With 4.9 million tonnes of pot ale being produced per annum in Scotland alone, it presents a difficult disposal challenge for the industry. Pot ale has high... Read More about Exploring the potential resource recovery from pot ale utilising microalgae and novel LED photobioreactors..

A European multi lake survey dataset of environmental variables, phytoplankton pigments and cyanotoxins. (2018)
Journal Article
MANTZOUKI, E., CAMPBELL, J., VAN LOON, E.E., VISSER, P. and IBELINGS, B. 2018. A European multi lake survey dataset of environmental variables, phytoplankton pigments and cyanotoxins. Scientific data [online], 5, article ID 180226. Available from: https://doi.org/10.1038/sdata.2018.226

Under ongoing climate change and increasing anthropogenic activity, which continuously challenge ecosystem resilience, an in-depth understanding of ecological processes is urgently needed. Lakes, as providers of numerous ecosystem services, face mult... Read More about A European multi lake survey dataset of environmental variables, phytoplankton pigments and cyanotoxins..

Enhancing photocatalytic degradation of the cyanotoxin microcystin-LR with the addition of sulfate-radical generating oxidants. (2018)
Journal Article
ANTONIOU, M.G., BORAEI, I., SOLAKIDOU, M., DELIGIANNAKIS, Y., ABHISHEK, M., LAWTON, L.A. and EDWARDS, C. 2018. Enhancing photocatalytic degradation of the cyanotoxin microcystin-LR with the addition of sulfate-radical generating oxidants. Journal of hazardous materials [online], 360, pages 461-470. Available from: https://doi.org/10.1016/j.jhazmat.2018.07.111

This study investigated the coupling of sulfate radical generating oxidants, (persulfate, PS and peroxymonosulfate, PMS) with TiO2 photocatalysis for the degradation of microcystin-LR (MC-LR). Treatment efficiency was evaluated by estimating the elec... Read More about Enhancing photocatalytic degradation of the cyanotoxin microcystin-LR with the addition of sulfate-radical generating oxidants..

Cyanopeptolins with trypsin and chymotrypsin inhibitory activity from the cyanobacterium nostoc edaphicum CCNP1411. (2018)
Journal Article
MAZUR-MARZEC, H., FIDOR, A., CEGLOWSKA, M., WIECZERZAK, E., KROPIDLOWSKA, M., GOUA, M., MACASKILL, J. and EDWARDS, C. 2018. Cyanopeptolins with trypsin and chymotrypsin inhibitory activity from the cyanobacterium nostoc edaphicum CCNP1411. Marine drugs [online], 16(7), article number 220. Available from: https://doi.org/10.3390/md16070220

Cyanopeptolins (CPs) are one of the most frequently occurring cyanobacterial peptides, many of which are inhibitors of serine proteases. Some CP variants are also acutely toxic to aquatic organisms, especially small crustaceans. In this study, thirte... Read More about Cyanopeptolins with trypsin and chymotrypsin inhibitory activity from the cyanobacterium nostoc edaphicum CCNP1411..

Temperature effects explain continental scale distribution of cyanobacterial toxins. (2018)
Journal Article
MANTZOUKI, E., LÜRLING, M., FASTNER, J., DE SENERPONT DOMIS, L., IBELINGS, B.W., TEURLINCX, S. and CHMURA, D. 2018. Temperature effects explain continental scale distribution of cyanobacterial toxins. Toxins [online], 10(4), article number 156. Available from: https://doi.org/10.3390/toxins10040156

Insight into how environmental change determines the production and distribution of cyanobacterial toxins is necessary for risk assessment. Management guidelines currently focus on hepatotoxins (microcystins). Increasing attention is given to other c... Read More about Temperature effects explain continental scale distribution of cyanobacterial toxins..

Cell lysis and detoxification of cyanotoxins using a novel combination of microbubble generation and plasma microreactor technology for ozonation. (2018)
Journal Article
PANDHAL, J., SISWANTO, A., KUVSHINOV, D., ZIMMERMAN, W.B., LAWTON, L. and EDWARDS, C. 2018. Cell lysis and detoxification of cyanotoxins using a novel combination of microbubble generation and plasma microreactor technology for ozonation. Frontiers in microbiology [online], 9, article number 678. Available from: https://doi.org/10.3389/fmicb.2018.00678

There has been a steady rise in the global incidences of algal blooms and, worryingly, there is increasing evidence that changes in the global climate are leading to a shift toward cyanobacterial blooms. Many cyanobacterial genera are harmful, produc... Read More about Cell lysis and detoxification of cyanotoxins using a novel combination of microbubble generation and plasma microreactor technology for ozonation..

Development and single-laboratory validation of a UHPLC-MS/MS method for quantitation of microcystins and nodularin in natural water, cyanobacteria, shellfish and algal supplement tablet powders. (2017)
Journal Article
TURNER, A.D., WAACK, J., LEWIS, A., EDWARDS, C. and LAWTON, L. 2018. Development and single-laboratory validation of a UHPLC-MS/MS method for quantitation of microcystins and nodularin in natural water, cyanobacteria, shellfish and algal supplement tablet powders. Journal of chromatography B [online], 1074-1075, pages 111-123. Available from: https://doi.org/10.1016/j.jchromb.2017.12.032

A simple, rapid UHPLC-MS/MS method has been developed and optimised for the quantitation of microcystins and nodularin in wide variety of sample matrices. Microcystin analogues targeted were MC-LR, MC-RR, MC-LA, MC-LY, MC-LF, LC-LW, MC-YR, MC-WR, [As... Read More about Development and single-laboratory validation of a UHPLC-MS/MS method for quantitation of microcystins and nodularin in natural water, cyanobacteria, shellfish and algal supplement tablet powders..

Uptake and depuration of cyanotoxins in the common blue mussel Mytilus edulis. (2017)
Thesis
WAACK, J. 2017. Uptake and depuration of cyanotoxins in the common blue mussel Mytilus edulis. Robert Gordon University, PhD thesis.

Cyanobacteria produce a variety of secondary metabolites that possess - amongst other things - antifungal, antibacterial and antiviral properties. Being primary producers, they are also a vital component within the food web. However, certain strains... Read More about Uptake and depuration of cyanotoxins in the common blue mussel Mytilus edulis..

Effects of temperature and salinity on the production of cell biomass, chlorophyll-a and intra- and extracellular nodularins (NOD) and nodulopeptin 901 produced by Nodularia spumigena KAC 66. (2017)
Journal Article
HAMEED, S., LAWTON, L.A., EDWARDS, C., KHAN, A., FAROOQ, U. and KHAN, F.A. 2017. Effects of temperature and salinity on the production of cell biomass, chlorophyll-a and intra- and extracellular nodularins (NOD) and nodulopeptin 901 produced by Nodularia spumigena KAC 66. Journal of applied phycology [online], 29(4), pages 1801-1810. Available from: https://doi.org/10.1007/s10811-017-1115-5

Nodularia spumigena is one of the dominant toxic cyanobacteria which produce blooms in the Baltic Sea, a brackish water body, particularly in late summer. Nodularia spp. are known to produce hepatotoxic nodularins (NODs) and other bioactive peptides... Read More about Effects of temperature and salinity on the production of cell biomass, chlorophyll-a and intra- and extracellular nodularins (NOD) and nodulopeptin 901 produced by Nodularia spumigena KAC 66..

Hepatotoxic-microcystins in two drinking water reservoirs in the central region of Ghana. (2017)
Journal Article
ADDICO, G.N.D., LAWTON, L. and EDWARDS, C. 2017. Hepatotoxic-microcystins in two drinking water reservoirs in the central region of Ghana. Toxicology and forensic medicine [online], 2(1), pages 1-11. Available from: https://doi.org/10.17140/TFMOJ-2-111

Background: Microcystins are cyclic peptides containing seven amino acids with the condensation of two terminal amino acids of the linear peptide to form a cyclic compound. The cyclic nature of microcystins suggests that they are highly stable in wat... Read More about Hepatotoxic-microcystins in two drinking water reservoirs in the central region of Ghana..

Archaeological medicinal earths as antibacterial agents: the case of the Basel Lemnian sphragides. (2017)
Journal Article
PHOTOS-JONES, E., EDWARDS, C., HANER, F., LAWTON, L., KEAN, C., LEANORD, A. and PERDIKATSIS, V. 2017. Archaeological medicinal earths as antibacterial agents: the case of the Basel Lemnian sphragides. Geological society: special publications. Geology and medicine: historical connections [online], 452, pages 141-153. Available from: https://doi.org/10.1144/SP452.6

This paper presents the scientific investigation of three Lemnian sphragides (terra sigillata), a famed medicinal clay (earth) of antiquity, dated to the 16th-17th century, and presently in the collection of the Museum for the History of Pharmacy of... Read More about Archaeological medicinal earths as antibacterial agents: the case of the Basel Lemnian sphragides..

Evidence for functional drift of bacterial isolates in response to cyanobacterial microcystin-lr and multiple peptide degradation in paucibacter toxinivorans. (2016)
Thesis
KREITZ, J. 2016. Evidence for functional drift of bacterial isolates in response to cyanobacterial microcystin-lr and multiple peptide degradation in paucibacter toxinivorans. Robert Gordon University, MPhil thesis.

Bacterial bioremediation has been proposed as an efficient, low cost and ecologically safe method to clean vital water reservoirs from cyanobacterial peptide toxins microcystins (MCs). In previous work carried out in 2008 several bacteria were isolat... Read More about Evidence for functional drift of bacterial isolates in response to cyanobacterial microcystin-lr and multiple peptide degradation in paucibacter toxinivorans..

Accumulation and detoxication responses of the gastropod Lymnaea stagnalis to single and combined exposures to natural (cyanobacteria) and anthropogenic (the herbicide RoundUp® Flash) stressors. (2016)
Journal Article
LANCE, E., DESPRAT, J., HOLBECH, B.F., GERARD, C., BORMANS, M., LAWTON, L.A., EDWARDS, C. and WIEGAND, C. 2016. Accumulation and detoxication responses of the gastropod Lymnaea stagnalis to single and combined exposures to natural (cyanobacteria) and anthropogenic (the herbicide RoundUp® Flash) stressors. Aquatic toxicology [online], 177, pages 116-124. Available from: https://doi.org/10.1016/j.aquatox.2016.05.024

Freshwater gastropods are increasingly exposed to multiple stressors in the field such as the herbicide glyphosate in Roundup formulations and cyanobacterial blooms either producing or not producing microcystins (MCs), potentially leading to interact... Read More about Accumulation and detoxication responses of the gastropod Lymnaea stagnalis to single and combined exposures to natural (cyanobacteria) and anthropogenic (the herbicide RoundUp® Flash) stressors..

Lack of functional redundancy in the relationship between microbial diversity and ecosystem functioning. (2016)
Journal Article
DELGADO-BAQUERIZO, M., GIARAMIDA, L., REICH, P.B., KHACHANE, A.N., HAMONTS, K., EDWARDS, C., LAWTON, L.A. and SINGH, B.K. 2016. Lack of functional redundancy in the relationship between microbial diversity and ecosystem functioning. Journal of ecology [online], 104(4), pages 936-946. Available from: https://doi.org/10.1111/1365-2745.12585

1. Biodiversity is declining worldwide with detrimental effects on ecosystems. However, we lack a quantitative understanding of the shape of the relationship between microbial biodiversity and ecosystem function (BEF). This limits our understanding o... Read More about Lack of functional redundancy in the relationship between microbial diversity and ecosystem functioning..

An investigation on the effects of cyanopeptides on the growth and secondary metabolite production of Microcystis aeruginosa PCC7806. (2016)
Thesis
ARIF ABDUL RAHMAN, T. 2016. An investigation on the effects of cyanopeptides on the growth and secondary metabolite production of Microcystis aeruginosa PCC7806. Robert Gordon University, PhD thesis.

Cyanobacteria are one of the oldest forms of photosynthetic life and may have contributed significantly to the evolution of oxygen into the then anoxic environment. Cyanobacteria are also one of the best sources of natural secondary metabolites (cyan... Read More about An investigation on the effects of cyanopeptides on the growth and secondary metabolite production of Microcystis aeruginosa PCC7806..

A collaborative evaluation of LC-MS/MS based methods for BMAA analysis: soluble bound BMAA found to be an important fraction. (2016)
Journal Article
FAASSEN, E.J., ANTONIOU, M.G., BEEKMAN-LUKASSEN, W., BLAHOVA, L., CHERNOVA, E., CHRISTOPHORIDIS, C., COMBES, A., EDWARDS, C., FASTNER, J., HARMSEN, J., HISKIA, A., ILAG, L.L., KALOUDIS, T., LOPICIC, S., LURLING, M., MAZUR-MARZEC, H., MERILUOTO, J., POROJAN, C., VINER-MOZZINI, Y. and ZGUNA, N. 2016. A collaborative evaluation of LC-MS/MS based methods for BMAA analysis: soluble bound BMAA found to be an important fraction. Marine drugs [online], 14(3), article 45. Available from: https://doi.org/10.3390/md14030045

Exposure to β-Ν-methylamino-l-alanine (BMAA) might be linked to the incidence of amyotrophic lateral sclerosis, Alzheimer's disease and Parkinson's disease. Analytical chemistry plays a crucial role in determining human BMAA exposure and the associat... Read More about A collaborative evaluation of LC-MS/MS based methods for BMAA analysis: soluble bound BMAA found to be an important fraction..

Rapid bioassay-guided isolation of antibacterial clerodane type diterpenoid from Dodonaea viscosa (L.) Jaeq. (2015)
Journal Article
KHURRAM, M., LAWTON, L.A., EDWARDS, C., IRITI, M., HAMEED, A., KHAN, M.A., KHAN, F.A. and RAHMAN, S.U. 2015. Rapid bioassay-guided isolation of antibacterial clerodane type diterpenoid from Dodonaea viscosa (L.) Jaeq. International journal of molecular science [online], 16(9), pages 20290-20307. Available from: https://doi.org/10.3390/ijms160920290

Plant extracts are complex matrices and, although crude extracts are widely in use, purified compounds are pivotal in drug discovery. This study describes the application of automated preparative-HPLC combined with a rapid off-line bacterial bioassay... Read More about Rapid bioassay-guided isolation of antibacterial clerodane type diterpenoid from Dodonaea viscosa (L.) Jaeq..

Photocatalytic degradation of eleven microcystin variants and nodularin by TiO2 coated glass microspheres. (2015)
Journal Article
PESTANA, C.J., EDWARDS, C., PRABHU, R., ROBERTSON, P.K.J. and LAWTON, L.A. 2015. Photocatalytic degradation of eleven microcystin variants and nodularin by TiO2 coated glass microspheres. Journal of hazardous materials [online], 300, pages 347-353. Available from: https://doi.org/10.1016/j.jhazmat.2015.07.016

Microcystins and nodularin are toxic cyanobacterial secondary metabolites produced by cyanobacteria that pose a threat to human health in drinking water. Conventional water treatment methods often fail to remove these toxins. Advanced oxidation proce... Read More about Photocatalytic degradation of eleven microcystin variants and nodularin by TiO2 coated glass microspheres..

Overcoming the seasonal variations in fitness of the amphipod Corophium Volutator as an environmental toxicology test species using laboratory cultured specimens. (2014)
Thesis
MCGEE, D. 2014. Overcoming the seasonal variations in fitness of the amphipod Corophium Volutator as an environmental toxicology test species using laboratory cultured specimens. Robert Gordon University, MRes thesis.

The marine amphipod Corophium volutator is an important source of food for many fish and wading birds, making it an important species in an estuarine environment and a relevant toxicological test species. Historical data has indicated that seasonal v... Read More about Overcoming the seasonal variations in fitness of the amphipod Corophium Volutator as an environmental toxicology test species using laboratory cultured specimens..

Optimisation of high value metabolite production from benthic marine dinoflagellate Prorocentrum lima. (2014)
Thesis
PRAPTIWI, R.A. 2014. Optimisation of high value metabolite production from benthic marine dinoflagellate Prorocentrum lima. Robert Gordon University, PhD thesis.

Toxins produced by harmful algal blooms (HABs) are known to pose contamination risks to seafood products (e.g. fish and shellfish) consumed by human. In order to control contamination risks, monitoring regimes have to be performed rigorously. The eff... Read More about Optimisation of high value metabolite production from benthic marine dinoflagellate Prorocentrum lima..

A continuous flow packed bed photocatalytic reactor for the destruction of 2-methylisoborneol and geosmin utilising pelletised TiO2. (2013)
Journal Article
PESTANA, C.J., ROBERTSON, P.K.J., EDWARDS, C., WILHELM, W., MCKENZIE, C. and LAWTON, L.A. 2014. A continuous flow packed bed photocatalytic reactor for the destruction of 2-methylisoborneol and geosmin utilising pelletised TiO2. Chemical engineering journal [online], 235, pages 293-298. Available from: https://doi.org/10.1016/j.cej.2013.09.041

Taste and odour compounds, especially geosmin (GSM) and 2-methylisoborneol (2-MIB), cause major problems in both drinking water and aquaculture industries world-wide. Aquaculture in particular has experienced significant financial losses due to the a... Read More about A continuous flow packed bed photocatalytic reactor for the destruction of 2-methylisoborneol and geosmin utilising pelletised TiO2..

Freshwater bacterial diversity, functions and stability. (2013)
Thesis
GIARAMIDA, L. 2013. Freshwater bacterial diversity, functions and stability. Robert Gordon University, PhD thesis.

Biodiversity is declining worldwide with detrimental effects on ecosystems functions and services that it sustains. The relationship between biodiversity and freshwater purification remains unclear. Freshwater purification is of paramount importance... Read More about Freshwater bacterial diversity, functions and stability..

Investigation of the production and isolation of bioactive compounds from cyanobacteria. (2013)
Thesis
HAMEED, S. 2013. Investigation of the production and isolation of bioactive compounds from cyanobacteria. Robert Gordon University, PhD thesis.

Due to heavy nutrient load and adverse climate change the occurrence of toxic cyanobacterial blooms have significantly increased during the last decades. Nodularia spumigena is one of the dominant toxic cyanobacteria which produces massive and inhere... Read More about Investigation of the production and isolation of bioactive compounds from cyanobacteria..

Investigation of novel methods to remove the cyanotoxin, Cylindrospermopsin, from drinking water. (2013)
Thesis
CHANDU, V.C.P 2013. Investigation of novel methods to remove the cyanotoxin, Cylindrospermopsin, from drinking water. Robert Gordon University, PhD thesis.

The widespread distribution of cyanobacteria and their toxic effects on humans has become a major concern for researchers. Cyanobacteria are a group of oxygenic phototrophic bacteria that exhibit an enormous diversity in shapes and arrangements and o... Read More about Investigation of novel methods to remove the cyanotoxin, Cylindrospermopsin, from drinking water..

Monitoring and regulating cyanobacterial metabolites (microcystins and geosmin) in aquatic systems. (2012)
Thesis
PESTANA, C.J. 2012. Monitoring and regulating cyanobacterial metabolites (microcystins and geosmin) in aquatic systems. Robert Gordon University, PhD thesis.

Cyanobacterial secondary metabolites can cause serious harm to animals and humans (cyanotoxins) and can have a major financial impact on the potable water and aquaculture industries (taste and odour compounds). Understanding the factors that affect c... Read More about Monitoring and regulating cyanobacterial metabolites (microcystins and geosmin) in aquatic systems..

An investigation into the biodegradation of peptide cyanotoxins (microcystins and nodularin) by novel gram-positive bacteria. (2012)
Thesis
WELGAMAGE DON, A.C.D. 2012. An investigation into the biodegradation of peptide cyanotoxins (microcystins and nodularin) by novel gram-positive bacteria. Robert Gordon University, PhD thesis.

Cyanobacterial secondary metabolites, microcystins (MC) and nodularin (NOD) have become common contaminants in most aquatic ecosystems over recent years presenting a hazard to animal and human health. Unfortunately, these chemically diverse peptide h... Read More about An investigation into the biodegradation of peptide cyanotoxins (microcystins and nodularin) by novel gram-positive bacteria..

Purification, detection and biological effects of cyanobacterial toxins. (1999)
Thesis
MCELHINEY, J. 1999. Purification, detection and biological effects of cyanobacterial toxins. Robert Gordon University, PhD thesis.

Dense growths of cyanobacteria (blue-green algae), known as blooms, commonly occur in fresh and brackish waters throughout the world. Cyanobacterial blooms present a considerable threat to water quality as many species produce toxins. These toxins ha... Read More about Purification, detection and biological effects of cyanobacterial toxins..

Clean water, green future: the story of bio-based treatment. [Video recording]
Digital Artefact
EDWARDS, C., MOORE, J., LAWTON, L. and MONTGOMERY, L. 2023. Clean water, green future: the story of bio-based treatment. [Video recording]. Research revealed, S01E01. Hosted on YouTube [online]. Available from: https://www.youtube.com/watch?v=OeLw7c9VMR8

This video was created as the first of a new series by RGU, "Research Revealed", which seeks to highlight the breadth of high impact research being undertaken across the University. This video focuses on a project within the School of Pharmacy and Li... Read More about Clean water, green future: the story of bio-based treatment. [Video recording].