Rapid uptake and slow depuration: health risks following cyanotoxin accumulation in mussels? (2020)
Journal Article
CAMACHO-MUÑOZ, D., WAACK, J., TURNER, A.D., LEWIS, A.M., LAWTON, L.A. and EDWARDS, C. 2021. Rapid uptake and slow depuration: health risks following cyanotoxin accumulation in mussels? Environmental pollution [online], 271, article ID 116400. Available from: https://doi.org/10.1016/j.envpol.2020.116400

Freshwater cyanobacteria produce highly toxic secondary metabolites, which can be transported downstream by rivers and waterways into the sea. Estuarine and coastal aquaculture sites exposed to toxic cyanobacteria raise concerns that shellfish may ac... Read More about Rapid uptake and slow depuration: health risks following cyanotoxin accumulation in mussels?.

Anatoxin-a degradation by using titanium dioxide. (2020)
Journal Article
KAMINSKI, A., EDWARDS, C., CHRAPUSTA-SREBRNY, E. and LAWTON, L.A. 2021. Anatoxin-a degradation by using titanium dioxide. Science of the total environment [online], 756, article ID 143590. Available from: https://doi.org/10.1016/j.scitotenv.2020.143590

Advanced oxidation processes, such as using titanium dioxide (TiO2) photocatalysis, are being developed to reduce or eliminate the toxicity of treated water. In this study, the removal of purified anatoxin-a (ANTX-a), live Dolichospermum flos-aquae c... Read More about Anatoxin-a degradation by using titanium dioxide..

Oxidative stress in the cyanobacterium microcystis aeruginosa PCC 7813: comparison of different analytical cell stress detection assays. (2020)
Journal Article
MENEZES, I., MAXWELL-MCQUEEN, D., CAPELO-NETO, J., PESTANA, C.J., EDWARDS, C. and LAWTON, L.A. [2020]. Oxidative stress in the cyanobacterium Microcystis aeruginosa PCC 7813: comparison of different analytical cell stress detection assays. Chemosphere [online], In Press. Available from: https://doi.org/10.1016/j.chemosphere.2020.128766

Cyanobacterial blooms are observed when high cell densities occur and are often dangerous to human and animal health due to the presence of cyanotoxins. Conventional drinking water treatment technology struggles to efficiently remove cyanobacterial c... Read More about Oxidative stress in the cyanobacterium microcystis aeruginosa PCC 7813: comparison of different analytical cell stress detection assays..

Graphitic-C3N4 coated floating glass beads for photocatalytic destruction of synthetic and natural organic compounds in water under UV light. (2020)
Journal Article
HUI, J., PESTANA, C.J., CAUX, M., GUNARATNE, H.Q.N., EDWARDS, C., ROBERTSON, P.K.J., LAWTON, L.A. and IRVINE, J.T.S. 2020. Graphitic-C3N4 coated floating glass beads for photocatalytic destruction of synthetic and natural organic compounds in water under UV light. Journal of photochemistry and photobiology A: chemistry [online], 405, article ID 112935. Available from: https://doi.org/10.1016/j.jphotochem.2020.112935

Many drinking water reservoirs can contain organic pollutants such as artificial synthesized dye and drugs. On the other hand, some naturally occurring microorganisms such as cyanobacteria, are capable of producing toxic secondary metabolites (cyanot... Read More about Graphitic-C3N4 coated floating glass beads for photocatalytic destruction of synthetic and natural organic compounds in water under UV light..

Degradation of microcystin-LR and cylindrospermopsin by continuous flow UV-A photocatalysis over immobilised TiO2. (2020)
Journal Article
CAMACHO-MUÑOZ, D., FERVERS, A.-S., PESTANA, C.J., EDWARDS, C. and LAWTON, L.A. 2020. Degradation of microcystin-LR and cylindrospermopsin by continuous flow UV-A photocatalysis over immobilised TiO2. Journal of environmental management [online], 276, article ID 111368. Available from: https://doi.org/10.1016/j.jenvman.2020.111368

The increasing presence of freshwater toxins have brought new challenges to preserve water quality due to their potential impact on the environment and human health. Two commonly occurring cyanotoxins, microcystin-LR and cylindrospermopsin, with diff... Read More about Degradation of microcystin-LR and cylindrospermopsin by continuous flow UV-A photocatalysis over immobilised TiO2..

Photocatalytic removal of the cyanobacterium Microcystis aeruginosa PCC7813 and four microcystins by TiO2 coated porous glass beads with UV-LED irradiation. (2020)
Journal Article
PESTANA, C.J., PORTELA NORONHA, J., HUI, J., EDWARDS, C., GUNARATNE, H.Q.N., IRVINE, J.T.S., ROBERTSON, P.K.J., CAPELO-NETO, J. and LAWTON, L.A. 2020. Photocatalytic removal of the cyanobacterium Microcystis aeruginosa PCC7813 and four microcystins by TiO2 coated porous glass beads with UV-LED irradiation. Science of the total environment [online], 745, article number 141154. Available from: https://doi.org/10.1016/j.scitotenv.2020.141154

Cyanobacteria and their toxic secondary metabolites are a challenge in water treatment due to increased biomass and dissolved metabolites in the raw water. Retrofitting existing water treatment infrastructure is prohibitively expensive or unfeasible,... Read More about Photocatalytic removal of the cyanobacterium Microcystis aeruginosa PCC7813 and four microcystins by TiO2 coated porous glass beads with UV-LED irradiation..

Exploitation of underused Streptomyces through a combined metabolomics-genomics workflow to enhance natural product diversity. (2020)
Thesis
BURNS, J. 2020. Exploitation of underused streptomyces through a combined metabolomics-genomics workflow to enhance natural product diversity. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

The genus Streptomyces is the source of approximately two-thirds of all clinically-used antibiotics. Despite being the source of so many specialised metabolites, genomic analysis indicates that most Streptomyces strains have the potential to produce... Read More about Exploitation of underused Streptomyces through a combined metabolomics-genomics workflow to enhance natural product diversity..

Degradation of okadaic acid in seawater by UV/TiO2 photocatalysis: proof of concept. (2020)
Journal Article
CAMACHO-MUÑOZ, D., LAWTON, L.A. and EDWARDS, C. 2020. Degradation of okadaic acid in seawater by UV/TiO2 photocatalysis: proof of concept. Science of the total environment [online], 733, article ID 139346. Available from: https://doi.org/10.1016/j.scitotenv.2020.139346

The consumption of contaminated shellfish with marine toxins causes adverse socioeconomical, environmental and health impacts. The marine toxin okadaic acid (OA) provokes diarrhetic shellfish poisoning (DSP) syndrome characterized by severe gastroint... Read More about Degradation of okadaic acid in seawater by UV/TiO2 photocatalysis: proof of concept..

Cross talk: two way allelopathic interactions between toxic Microcystis and Daphnia. (2020)
Journal Article
BOJADZIJA SAVIC, G., BORMANS, M., EDWARDS, C., LAWTON, L., BRIAND, E. and WIEGAND, C. 2020. Cross talk: two way allelopathic interactions between toxic Microcystis and Daphnia. Harmful algae [online], 94, article ID 101803. Available from: https://doi.org/10.1016/j.hal.2020.101803

Due to eutrophication, freshwater ecosystems frequently experience cyanobacterial blooms, many of which produce bioactive metabolites that can affect vertebrates and invertebrates life traits. Zooplankton are able to develop tolerance as a physiologi... Read More about Cross talk: two way allelopathic interactions between toxic Microcystis and Daphnia..

'All in one' photo-reactor pod containing TiO2 coated glass beads and LEDs for continuous photocatalytic destruction of cyanotoxins in water. (2020)
Journal Article
GUNARATNE, H.Q.N., PESTANA, C.J., SKILLEN, N., HUI, J., SARAVANAN, S., EDWARDS, C., IRVINE, J.T.S., ROBERTSON, P.K.J. and LAWTON, L.A. 2020. ‘All in one’ photo-reactor pod containing TiO2 coated glass beads and LEDs for continuous photocatalytic destruction of cyanotoxins in water. Environmental science: water research and technology [online], 6(4), pages 945-950. Available from: https://doi.org/10.1039/c9ew00711c

Blooms of blue-green algae (cyanobacteria) in water reservoirs frequently produce highly toxic secondary metabolites including microcystins which have resulted in both human and animal fatalities. To tackle this global problem, we present here a viab... Read More about 'All in one' photo-reactor pod containing TiO2 coated glass beads and LEDs for continuous photocatalytic destruction of cyanotoxins in water..

Phosphate and nitrate supplementations to evaluate the effect on cell biomass, intra and extracellular nodularin and nodulopeptin 901 produced by the cyanobacterium Nodularia spumigena KAC 66. (2019)
Journal Article
HAMEED, S., LAWTON, L.A. and EDWARDS, C. 2020. Phosphate and nitrate supplementations to evaluate the effect on cell biomass, intra and extracellular nodularin and nodulopeptin 901 produced by the cyanobacterium Nodularia spumigena KAC 66. Journal of applied phycology [online], 32(2), pages 937-950. Available from: https://doi.org/10.1007/s10811-019-02008-z

Blooms of the cyanobacterium Nodularia spumigena occur regularly in the Baltic Sea typically producing a wide range of bioactive peptides including the hepatotoxin nodularin (NOD), spumigins, anabaenopeptins and nodulopeptins (molecular weights: 917,... Read More about Phosphate and nitrate supplementations to evaluate the effect on cell biomass, intra and extracellular nodularin and nodulopeptin 901 produced by the cyanobacterium Nodularia spumigena KAC 66..

Daphnia magna exudates impact physiological and metabolic changes in microcystis aeruginosa. (2019)
Journal Article
SAVIC, G.B., EDWARDS, C., BRIAND, E., LAWTON, L., WIEGAND, C. and BORMANS, M. 2019. Daphnia magna exudates impact physiological and metabolic changes in microcystis aeruginosa. Toxins [online], 11(7), article number 421. Available from: https://doi.org/10.3390/toxins11070421

While the intracellular function of many toxic and bioactive cyanobacterial metabolites is not yet known, microcystins have been suggested to have a protective role in the cyanobacterial metabolism, giving advantage to toxic over nontoxic strains und... Read More about Daphnia magna exudates impact physiological and metabolic changes in microcystis aeruginosa..

Exploring the potential resource recovery from pot ale utilising microalgae and novel LED photobioreactors. (2019)
Thesis
MCNERNEY, C.C. 2019. Exploring the potential resource recovery from pot ale utilising microalgae and novel LED photobioreactors. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

Pot ale is a protein-rich, high-carbon and acidic (pH 3.5) by-product of the whisky industry. With 4.9 million tonnes of pot ale being produced per annum in Scotland alone, it presents a difficult disposal challenge for the industry. Pot ale has high... Read More about Exploring the potential resource recovery from pot ale utilising microalgae and novel LED photobioreactors..

A European multi lake survey dataset of environmental variables, phytoplankton pigments and cyanotoxins. (2018)
Journal Article
MANTZOUKI, E., CAMPBELL, J., VAN LOON, E.E., VISSER, P. and IBELINGS, B. 2018. A European multi lake survey dataset of environmental variables, phytoplankton pigments and cyanotoxins. Scientific data [online], 5, article ID 180226. Available from: https://doi.org/10.1038/sdata.2018.226

Under ongoing climate change and increasing anthropogenic activity, which continuously challenge ecosystem resilience, an in-depth understanding of ecological processes is urgently needed. Lakes, as providers of numerous ecosystem services, face mult... Read More about A European multi lake survey dataset of environmental variables, phytoplankton pigments and cyanotoxins..

Enhancing photocatalytic degradation of the cyanotoxin microcystin-LR with the addition of sulfate-radical generating oxidants. (2018)
Journal Article
ANTONIOU, M.G., BORAEI, I., SOLAKIDOU, M., DELIGIANNAKIS, Y., ABHISHEK, M., LAWTON, L.A. and EDWARDS, C. 2018. Enhancing photocatalytic degradation of the cyanotoxin microcystin-LR with the addition of sulfate-radical generating oxidants. Journal of hazardous materials [online], 360, pages 461-470. Available from: https://doi.org/10.1016/j.jhazmat.2018.07.111

This study investigated the coupling of sulfate radical generating oxidants, (persulfate, PS and peroxymonosulfate, PMS) with TiO2 photocatalysis for the degradation of microcystin-LR (MC-LR). Treatment efficiency was evaluated by estimating the elec... Read More about Enhancing photocatalytic degradation of the cyanotoxin microcystin-LR with the addition of sulfate-radical generating oxidants..

Cyanopeptolins with trypsin and chymotrypsin inhibitory activity from the cyanobacterium nostoc edaphicum CCNP1411. (2018)
Journal Article
MAZUR-MARZEC, H., FIDOR, A., CEGLOWSKA, M., WIECZERZAK, E., KROPIDLOWSKA, M., GOUA, M., MACASKILL, J. and EDWARDS, C. 2018. Cyanopeptolins with trypsin and chymotrypsin inhibitory activity from the cyanobacterium nostoc edaphicum CCNP1411. Marine drugs [online], 16(7), article number 220. Available from: https://doi.org/10.3390/md16070220

Cyanopeptolins (CPs) are one of the most frequently occurring cyanobacterial peptides, many of which are inhibitors of serine proteases. Some CP variants are also acutely toxic to aquatic organisms, especially small crustaceans. In this study, thirte... Read More about Cyanopeptolins with trypsin and chymotrypsin inhibitory activity from the cyanobacterium nostoc edaphicum CCNP1411..

Temperature effects explain continental scale distribution of cyanobacterial toxins. (2018)
Journal Article
MANTZOUKI, E., IBELINGS, B.W., FASTNER, J., LÜRLING, M., DE SENERPONT DOMIS, L., TEURLINCX, S. and CHMURA, D. 2018. Temperature effects explain continental scale distribution of cyanobacterial toxins. Toxins [online], 10(4), article number 156. Available from: https://doi.org/10.3390/toxins10040156

Insight into how environmental change determines the production and distribution of cyanobacterial toxins is necessary for risk assessment. Management guidelines currently focus on hepatotoxins (microcystins). Increasing attention is given to other c... Read More about Temperature effects explain continental scale distribution of cyanobacterial toxins..

Cell lysis and detoxification of cyanotoxins using a novel combination of microbubble generation and plasma microreactor technology for ozonation. (2018)
Journal Article
PANDHAL, J., SISWANTO, A., KUVSHINOV, D., ZIMMERMAN, W.B., LAWTON, L. and EDWARDS, C. 2018. Cell lysis and detoxification of cyanotoxins using a novel combination of microbubble generation and plasma microreactor technology for ozonation. Frontiers in microbiology [online], 9, article number 678. Available from: https://doi.org/10.3389/fmicb.2018.00678

There has been a steady rise in the global incidences of algal blooms and, worryingly, there is increasing evidence that changes in the global climate are leading to a shift toward cyanobacterial blooms. Many cyanobacterial genera are harmful, produc... Read More about Cell lysis and detoxification of cyanotoxins using a novel combination of microbubble generation and plasma microreactor technology for ozonation..

Development and single-laboratory validation of a UHPLC-MS/MS method for quantitation of microcystins and nodularin in natural water, cyanobacteria, shellfish and algal supplement tablet powders. (2017)
Journal Article
TURNER, A.D., WAACK, J., LEWIS, A., EDWARDS, C. and LAWTON, L. 2018. Development and single-laboratory validation of a UHPLC-MS/MS method for quantitation of microcystins and nodularin in natural water, cyanobacteria, shellfish and algal supplement tablet powders. Journal of chromatography B [online], 1074-1075, pages 111-123. Available from: https://doi.org/10.1016/j.jchromb.2017.12.032

A simple, rapid UHPLC-MS/MS method has been developed and optimised for the quantitation of microcystins and nodularin in wide variety of sample matrices. Microcystin analogues targeted were MC-LR, MC-RR, MC-LA, MC-LY, MC-LF, LC-LW, MC-YR, MC-WR, [As... Read More about Development and single-laboratory validation of a UHPLC-MS/MS method for quantitation of microcystins and nodularin in natural water, cyanobacteria, shellfish and algal supplement tablet powders..

Uptake and depuration of cyanotoxins in the common blue mussel Mytilus edulis. (2017)
Thesis
WAACK, J. 2017. Uptake and depuration of cyanotoxins in the common blue mussel Mytilus edulis. Robert Gordon University, PhD thesis.

Cyanobacteria produce a variety of secondary metabolites that possess - amongst other things - antifungal, antibacterial and antiviral properties. Being primary producers, they are also a vital component within the food web. However, certain strains... Read More about Uptake and depuration of cyanotoxins in the common blue mussel Mytilus edulis..