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Age at onset of walking in infancy is associated with hip shape in early old age. (2019)
Journal Article
IRELAND, A., SAUNDERS, F.R., MUTHURI, S.G., PAVLOVA, A.V., HARDY, R.J., MARTIN, K.R., BARR, R.J., ADAMS, J.E., KUH, D., ASPDEN, R.M. GREGORY, J.S. and COOPER, R. 2019. Age at onset of walking in infancy is associated with hip shape in early old age. Journal of bone and mineral research [online], 34(3), pages 455-463. Available from: https://doi.org/10.1002/jbmr.3627

Bones' shapes and structures adapt to the muscle and reaction forces they experience during everyday movements. Onset of independent walking, at approximately 12 months, represents the first postnatal exposure of the lower limbs to the large forces a... Read More about Age at onset of walking in infancy is associated with hip shape in early old age..

Associations between back pain across adulthood and spine shape in early old age in a British birth cohort. (2018)
Journal Article
MUTHURI, S.G., PAVLOVA, A.V., SAUNDERS, F.R., HARDY, R.J., GREGORY, J.S., BARR, R.J., MARTIN, K.R., ADAMS, J.E., KUH, D., ASPDEN, R.M. and COOPER, R. 2018. Associations between back pain across adulthood and spine shape in early old age in a British birth cohort. Scientific reports [online], 8, article ID 16309. Available from: https://doi.org/10.1038/s41598-018-34628-9

We aimed to examine whether back pain across adulthood was associated with spine shape at age 60–64 years. Data were from 1405 participants in the MRC National Survey of Health and Development, a nationally representative British birth cohort. Back p... Read More about Associations between back pain across adulthood and spine shape in early old age in a British birth cohort..

Variation in lifting kinematics related to individual intrinsic lumbar curvature: an investigation in healthy adults. (2018)
Journal Article
PAVLOVA, A.V., MEAKIN, J.R., COOPER, K., BARR, R.J. and ASPDEN, R.M. 2018. Variation in lifting kinematics related to individual intrinsic lumbar curvature: an investigation in healthy adults. BMJ open sport and exercise medicine [online], 4(1), article number 000374. Available from: https://doi.org/10.1136/bmjsem-2018-000374

Objective: Lifting postures are frequently implicated in back pain. We previously related responses to a static load with intrinsic spine shape, and here we investigate the role of lumbar spine shape in lifting kinematics. Methods: Thirty healthy adu... Read More about Variation in lifting kinematics related to individual intrinsic lumbar curvature: an investigation in healthy adults..

Body mass index and waist circumference in early adulthood are associated with thoracolumbar spine shape at age 60-64: The Medical Research Council National Survey of Health and Development. (2018)
Journal Article
PAVLOVA, A.V., MUTHURI, S.G., COOPER, R., SAUNDERS, F.R., GREGORY, J.S., BARR, R.J., MARTIN, K.R., ADAMS, J.E., KUH, D., HARDY, R.J. and ASPDEN, R.M. 2018. Body mass index and waist circumference in early adulthood are associated with thoracolumbar spine shape at age 60-64: The Medical Research Council National Survey of Health and Development. PLoS ONE [online], 13(6), article ID e0197570. Available from: https://doi.org/10.1371/journal.pone.0197570

This study investigated associations between measures of adiposity from age 36 and spine shape at 60-64 years. Thoracolumbar spine shape was characterised using statistical shape modelling on lateral dual-energy x-ray absorptiometry images of the spi... Read More about Body mass index and waist circumference in early adulthood are associated with thoracolumbar spine shape at age 60-64: The Medical Research Council National Survey of Health and Development..

Associations between body mass index across adult life and hip shapes at age 60 to 64: evidence from the 1946 British birth cohort. (2017)
Journal Article
MUTHURI, S., SAUNDERS, F.R., HARDY, R.J., PAVLOVA, A.V., MARTIN, K.R., GREGORY, J.S., BARR, R.J, ADAMS, J.E., KUH, D., ASPDEN, R.M. and COOPER, R. 2017. Associations between body mass index across adult life and hip shapes at age 60 to 64: evidence from the 1946 British birth cohort. Bone [online], 105, pages 115-121. Available from: https://doi.org/10.1016/j.bone.2017.08.017

Objective: To examine the associations of body mass index (BMI) across adulthood with hip shapes at age 60-64years. Methods: Up to 1633 men and women from the MRC National Survey of Health and Development with repeat measures of BMI across adulthood... Read More about Associations between body mass index across adult life and hip shapes at age 60 to 64: evidence from the 1946 British birth cohort..

Statistical shape modelling of hip and lumbar spine morphology and their relationship in the MRC National Survey of Health and Development. (2017)
Journal Article
PAVLOVA, A.V., SAUNDERS, F.R., MUTHURI, S.G., GREGORY, J.S., BARR, R.J., MARTIN, K.R., HARDY, R.J., COOPER, R., ADAMS, J.E., KUH, D. and ASPDEN, R.M. 2017. Statistical shape modelling of hip and lumbar spine morphology and their relationship in the MRC National Survey of Health and Development. Journal of anatomy [online], 231(2), pages 248-259. Available from: https://doi.org/10.1111/joa.12631

The anatomical shape of bones and joints is important for their proper function, but quantifying this and detecting pathological variations is difficult to do. Numerical descriptions would also enable correlations between joint shapes to be explored.... Read More about Statistical shape modelling of hip and lumbar spine morphology and their relationship in the MRC National Survey of Health and Development..

The lumbar spine has an intrinsic shape specific to each individual that remains a characteristic throughout flexion and extension. (2014)
Journal Article
PAVLOVA, A.V., MEAKIN, J.R., COOPER, K., BARR, R.J. and ASPDEN, R.M. 2014. The lumbar spine has an intrinsic shape specific to each individual that remains a characteristic throughout flexion and extension. European spine journal [online], 23(Suppl 1), pages S26-S32. Available from: https://doi.org/10.1007/s00586-013-3162-1

We have previously shown that the lumbar spine has an intrinsic shape specific to the individual and characteristic of sitting, standing and supine postures. The purpose of this study was to test the hypothesis that this intrinsic shape is detectab... Read More about The lumbar spine has an intrinsic shape specific to each individual that remains a characteristic throughout flexion and extension..