Ahmed Hossam Eldin El-Bardissy
Evaluating the effectiveness of pneumococcal vaccines against hospitalization and intensive care unit admission in adults.
El-Bardissy, Ahmed Hossam Eldin; Al‐Adawi, Rana Moustafa; Shible, Ahmed Atef; Albu‐Mahmood, Zainab; Elgaily, Dina Eltayeb; Abdelaziz, Hani
Mrs RANA EZZAT AHMED AL-ADAWY email@example.com
Ahmed Atef Shible
Dina Eltayeb Elgaily
Objective: To evaluate the efficacy of pneumococcal vaccines concerning hospital or intensive care unit (ICU) admissions due to pneumonia after vaccination. Setting: Inpatient and ICUs at Hamad General Hospital. Methods: The retrospective study included adults who were vaccinated between June 2012 and June 2013. Patient records were reviewed for hospital or ICU admissions due to pneumonia 2 years before and after vaccination. Main outcomes measures: The primary outcome was to compare the rates of hospital and ICU admissions for pneumonia 2 years before and after vaccination. The secondary outcome was to evaluate the efficacy of pneumococcal vaccines against different comorbidities. Key findings: One hundred sixty-one patients were included with a dominant age group of 64–85 (52%) years old. Comorbidities reported were hypertension (HTN), diabetes mellitus (DM), chronic obstructive pulmonary disease (COPD) and asthma. The rate of hospital admission due to pneumonia was significantly reduced within 2 years after vaccination, 71–39% (P < 0.001). There was a trend towards reduced ICU admission (12.4–10.6%), but the results did not achieve statistical significance (P > 0.72). In diabetic, hypertensive and COPD/Asthma patients, there was a statistically significant reduction in hospitalization. Although there was a reduction in ICU admission for both commodities, the results did not achieve statistical significance. Conclusion: Adults who received pneumococcal vaccines experienced reduced rates of hospital versus ICU admissions due to pneumonia infection.
EL-BARDISSY, A.H.E., AL-ADAWI, R.M., SHIBLE, A.A., ALBU-MAHMOOD, Z., ELGAILY, D.E. and ABDELAZIZ, H. 2019. Evaluating the effectiveness of pneumococcal vaccines against hospitalization and intensive care unit admission in adults. Journal of pharmaceutical health services research [online], 10(4), pages 427-431. Available from: https://doi.org/10.1111/jphs.12321
|Journal Article Type||Article|
|Acceptance Date||Aug 28, 2019|
|Online Publication Date||Oct 7, 2019|
|Publication Date||Dec 31, 2019|
|Deposit Date||Jun 24, 2021|
|Publicly Available Date||Jun 24, 2021|
|Journal||Journal of Pharmaceutical Health Services Research|
|Publisher||Wiley Open Access|
|Peer Reviewed||Peer Reviewed|
|Keywords||Hospital admission and intensive care admission; Pneumococcal vaccine; Pneumonia|
EL-BARDISSY 2019 Evaluating the effectiveness (AAM)
This is the peer reviewed version of the following article: EL-BARDISSY, A.H.E., AL-ADAWI, R.M., SHIBLE, A.A., ALBU-MAHMOOD, Z., ELGAILY, D.E. and ABDELAZIZ, H. 2019. Evaluating the effectiveness of pneumococcal vaccines against hospitalization and intensive care unit admission in adults. Journal of pharmaceutical health services research, 10(4), pages 427-431, which has been published in final form at https://doi.org/10.1111/jphs.12321. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
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