Physiological and psychological outcomes of high intensity interval training in patients with heart failure compared to moderate continuous training and usual care: a systematic review with meta analysis.

Callum, Kara; Swinton, Paul; Gorely, Trish; Crabtree, Daniel; Leslie, Stephen

Abstract

An important component of secondary prevention of CVD (including HF) is comprehensive cardiac rehab, including exercise. Novel, individualised approaches are needed to increase uptake and adherence to exercise programmes. One area offering potential is HIIT. HIIT has been shown to be both safe and effective for improving cardiovascular fitness in both coronary artery disease and HF patients. The objective of this study was to provide a current and up-to-date evaluation of the physiological and psychological outcomes of HIIT in patients with HF, compared to MCT and UC. A secondary objective was to perform sub-group analyses comparing short and long HIIT protocols. A systematic review and meta-analysis of randomised controlled trials was undertaken. Medline, Embase, Scopus, CINAHL and SportDISCUS were searched up to July 2022. Trials were included if they carried out a HIIT intervention (defined at intensity ≥ 80% peak HR or ≥ 80% VO2peak) in HF patients (HFpEF or HFrEF) for at least 6 weeks. Comparator group was UC or MCT. HIIT was shown to be superior to MCT and UC for improving VO2peak (HIIT mean improvement 3.1mL.kg-1min-1). HITT was superior to MCT and UC for improving LVEF (HIIT mean improvement 5.7%). HIIT was superior to MCT and UC for improving HRQoL, using the MLHFQ (HIIT mean point change of -12.8). Subgroup analysis showed no difference between long and short HIIT. The study therefore concluded that HIIT improves VO2peak, LVEF and HRQoL in patients with HF, with the improvements seen in VO2peak and LVEF being superior in HIIT compared to MCT and UC.

Citation

CALLUM, K., SWINTON, P., GORELY, T., CRABTREE, D. and LESLIE, S. 2024. Physiological and psychological outcomes of high intensity interval training in patients with heart failure compared to moderate continuous training and usual care: a systematic review with meta analysis. Heart and lung [online], 64, pages 117-127. Available from: https://doi.org/10.1016/j.hrtlng.2023.12.002

• Journal Article Type: Article
• Acceptance Date: Dec 3, 2023
• Online Publication Date: Dec 29, 2023
• Publication Date: Apr 30, 2024
• Deposit Date: Dec 12, 2023
• Publicly Available Date: Dec 12, 2023
• Journal: Heart and lung
• Print ISSN: 0147-9563
• Electronic ISSN: 1527-3288
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 64
• Pages: 117-127
• DOI: https://doi.org/10.1016/j.hrtlng.2023.12.002
• Keywords: High intensity interval training (HIIT); Moderate continuous training; Heart failure; Exercise therapy; VO2peak; LVEF; HRQoL
• Public URL: https://rgu-repository.worktribe.com/output/2173838
• Additional Information: This article has been published with separate supporting information. This supporting information has been incorporated into a single file on this repository and can be found at the end of the file associated with this output.