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Misoprostol for miscarriage management in a woman with previous five cesarean deliveries: a case report and literature review.

AlSaad, Doua; Alobaidly, Sawsan; Abdulrouf, Palli; Thomas, Binny; Ahmed, Afif; AlHail, Moza

Authors

Doua AlSaad

Sawsan Alobaidly

Palli Abdulrouf

Binny Thomas

Afif Ahmed

Moza AlHail

Abstract

Background: Misoprostol is an effective medical method for the management of pregnancy loss. However, data on its efficacy and safety in women with previous cesarean deliveries are limited. Case presentation: We report a 36-year-old patient, gravida 11 para 6, with a diagnosis of missed miscarriage at 15 weeks of gestation. The patient had a significant obstetric history of previous five cesarean deliveries and uterine rupture. Following patient counseling about the medical and surgical options of managing her miscarriage, the patient opted for medical method. Low-dose misoprostol of 100 {aelig}g was inserted vaginally and repeated again after 6 hours. The patient had an uneventful complete miscarriage following the second dose of misoprostol. No uterine rupture, no extra vaginal bleeding, and no blood transfusion were observed. Conclusion: We conclude that adopting a low-dose misoprostol protocol could be potentially safe and effective in managing second trimester missed miscarriage in women with repeated cesarean deliveries and/or uterine rupture history. Further studies are needed to confirm these results.

Journal Article Type Article
Publication Date Dec 31, 2017
Journal Therapeutics and clinical risk management
Electronic ISSN 1178-203X
Publisher New Publisher Required
Peer Reviewed Peer Reviewed
Volume 13
Pages 625-627
Institution Citation ALSAAD, D., ALOBAIDLY, S., ABDULROUF, P., THOMAS, B., AHMED, A., ALHAIL, M. 2017. Misoprostol for miscarriage management in a woman with previous five cesarean deliveries: a case report and literature review. Therapeutics and clinical risk management [online], 13, pages 625-627. Available from: https://doi.org/10.2147/TCRM.S132294
DOI https://doi.org/10.2147/TCRM.S132294
Keywords Caesarean section; Uterine rupture; Prostaglandin E1; Misoprostol; Second trimester; Miscarriage; Abortion

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