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Misoprostol for miscarriage management in a woman with previous five cesarean deliveries: a case report and literature review.

AlSaad, Doua; Alobaidly, Sawsan; Abdulrouf, Palli; Thomas, Binny; Ahmed, Afif; AlHail, Moza

Authors

Doua AlSaad

Sawsan Alobaidly

Palli Abdulrouf

Binny Thomas

Afif Ahmed

Moza AlHail



Abstract

Background: Misoprostol is an effective medical method for the management of pregnancy loss. However, data on its efficacy and safety in women with previous cesarean deliveries are limited. Case presentation: We report a 36-year-old patient, gravida 11 para 6, with a diagnosis of missed miscarriage at 15 weeks of gestation. The patient had a significant obstetric history of previous five cesarean deliveries and uterine rupture. Following patient counseling about the medical and surgical options of managing her miscarriage, the patient opted for medical method. Low-dose misoprostol of 100 μg was inserted vaginally and repeated again after 6 hours. The patient had an uneventful complete miscarriage following the second dose of misoprostol. No uterine rupture, no extra vaginal bleeding, and no blood transfusion were observed. Conclusion: We conclude that adopting a low-dose misoprostol protocol could be potentially safe and effective in managing second trimester missed miscarriage in women with repeated cesarean deliveries and/or uterine rupture history. Further studies are needed to confirm these results.

Citation

ALSAAD, D., ALOBAIDLY, S., ABDULROUF, P., THOMAS, B., AHMED, A., ALHAIL, M. 2017. Misoprostol for miscarriage management in a woman with previous five cesarean deliveries: a case report and literature review. Therapeutics and clinical risk management [online], 13, pages 625-627. Available from: https://doi.org/10.2147/TCRM.S132294

Journal Article Type Article
Acceptance Date Feb 27, 2017
Online Publication Date May 9, 2017
Publication Date Dec 31, 2017
Deposit Date May 26, 2017
Publicly Available Date May 26, 2017
Journal Therapeutics and clinical risk management
Print ISSN 1176-6336
Electronic ISSN 1178-203X
Publisher Dove Medical Press
Peer Reviewed Peer Reviewed
Volume 13
Pages 625-627
DOI https://doi.org/10.2147/TCRM.S132294
Keywords Caesarean section; Uterine rupture; Prostaglandin E1; Misoprostol; Second trimester; Miscarriage; Abortion
Public URL http://hdl.handle.net/10059/2335

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