Misoprostol for miscarriage management in a woman with previous five cesarean deliveries: a case report and literature review.

AlSaad, Doua; Alobaidly, Sawsan; Abdulrouf, Palli; Thomas, Binny; Ahmed, Afif; AlHail, Moza

Abstract

Background: Misoprostol is an effective medical method for the management of pregnancy loss. However, data on its efficacy and safety in women with previous cesarean deliveries are limited. Case presentation: We report a 36-year-old patient, gravida 11 para 6, with a diagnosis of missed miscarriage at 15 weeks of gestation. The patient had a significant obstetric history of previous five cesarean deliveries and uterine rupture. Following patient counseling about the medical and surgical options of managing her miscarriage, the patient opted for medical method. Low-dose misoprostol of 100 μg was inserted vaginally and repeated again after 6 hours. The patient had an uneventful complete miscarriage following the second dose of misoprostol. No uterine rupture, no extra vaginal bleeding, and no blood transfusion were observed. Conclusion: We conclude that adopting a low-dose misoprostol protocol could be potentially safe and effective in managing second trimester missed miscarriage in women with repeated cesarean deliveries and/or uterine rupture history. Further studies are needed to confirm these results.

Citation

ALSAAD, D., ALOBAIDLY, S., ABDULROUF, P., THOMAS, B., AHMED, A., ALHAIL, M. 2017. Misoprostol for miscarriage management in a woman with previous five cesarean deliveries: a case report and literature review. Therapeutics and clinical risk management [online], 13, pages 625-627. Available from: https://doi.org/10.2147/TCRM.S132294

• Journal Article Type: Article
• Acceptance Date: Feb 27, 2017
• Online Publication Date: May 9, 2017
• Publication Date: Dec 31, 2017
• Deposit Date: May 26, 2017
• Publicly Available Date: May 26, 2017
• Journal: Therapeutics and clinical risk management
• Print ISSN: 1176-6336
• Electronic ISSN: 1178-203X
• Publisher: Dove Medical Press
• Peer Reviewed: Peer Reviewed
• Volume: 13
• Pages: 625-627
• DOI: https://doi.org/10.2147/TCRM.S132294
• Keywords: Caesarean section; Uterine rupture; Prostaglandin E1; Misoprostol; Second trimester; Miscarriage; Abortion
• Public URL: http://hdl.handle.net/10059/2335