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The hyponatremia epidemic: a frontier too far?

Drake-Holland, Angela J.; Noble, Mark I.M.


Angela J. Drake-Holland

Mark I.M. Noble


Hyponatremia is the most common electrolyte abnormality and is often neglected, especially in elderly and seemingly terminal patients. Hyponatremia can be asymptomatic or can cause symptoms ranging from nausea and lethargy to convulsions and coma. This condition has become increasingly common over time with a similar time course to the increase in adoption of low salt diets. The popularization of low salt may not be justified in people with normal kidney function in whom the compatible statistically based evidence that salt causes hypertension has been challenged by experimental evidence to the contrary.


DRAKE-HOLLAND, A.J. and NOBLE, M.I.M. 2016. The hyponatremia epidemic: a frontier too far? Frontiers in cardiovascular medicine [online], 3, pages 1-4. Available from:

Journal Article Type Article
Acceptance Date Sep 27, 2016
Online Publication Date Oct 7, 2016
Publication Date Oct 31, 2016
Deposit Date Aug 28, 2017
Publicly Available Date Aug 28, 2017
Journal Frontiers in cardiovascular medicine
Electronic ISSN 2297-055X
Publisher Frontiers Media
Peer Reviewed Peer Reviewed
Volume 3
Pages 1-4
Keywords Sodium; Salt; Elderly; Kidney function; Hypertension
Public URL


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