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Patient related factors affecting adherence to antimalarial medication in an urban estate in Ghana.

Amponsah, Alexandria O.; Vosper, Helen; Marfo, Afia F.A.


Alexandria O. Amponsah

Helen Vosper

Afia F.A. Marfo


Our aim was to measure the adherence to Artemisinin based Combination Therapy and to determine patient related factors that affect adherence. Three hundred (300) patients receiving ACT treatment dispensed from the community pharmacy were randomly selected and followed up on the fourth day after the start of their three-day therapy to assess adherence. Adherence was measured by pill count. Quantitative interviews using a semistructured questionnaire were used to assess patients' knowledge and beliefs on malaria and its treatment. Adherence levels to the ACTs were 57.3%. Patient related factors that affected adherence to ACTs were patients' knowledge on the dosage (P=0.007; v=0.457), efficacy (P=0.009; v=0.377), and side effects (P=0.000; v=0.403) of the ACTs used for the management of malaria, patients' awareness of the consequences of not completing the doses of antimalarial dispensed (P=0.001; v=0.309), and patients' belief that 'natural remedies are safer than medicines' and 'prescribers place too much trust in medicines.' There was no significant relationship between adherence and patients' knowledge on the causes, signs, and symptoms of malaria. There is the need for pharmacy staff to stress on these variables when counseling patients on antimalarials as these affect adherence levels.


AMPONSAH, A.O., VOSPER, H. and MARFO, A.F.A., 2015. Patient related factors affecting adherence to antimalarial medication in an urban estate in Ghana. Malaria research and treatment [online], 2015, Article ID 452539. Available from:

Journal Article Type Article
Acceptance Date Jan 28, 2015
Online Publication Date Feb 12, 2015
Publication Date Dec 31, 2015
Deposit Date Apr 22, 2015
Publicly Available Date Apr 22, 2015
Journal Malaria research and treatment
Print ISSN 2090-8075
Electronic ISSN 2044-4362
Publisher Hindawi
Peer Reviewed Peer Reviewed
Volume 2015
Article Number 452539
Public URL


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