Infographic. A systematic review and meta-analysis of the effect of ?-alanine supplementation on exercise capacity and performance.

Saunders, Bryan; Virgile, Adam; Elliott-Sale, Kirsty Jayne; Artioli, Guilherme Giannini; Swinton, Paul A.; Dolan, Eimear; Roschel, Hamilton; Sale, Craig; Gualano, Bruno

Abstract

Carnosine (?-alanyl-L-histidine) is an abundant compound in skeletal muscle, suggesting it plays an important role during exercise, with a key physiological role considered to be intracellular pH regulation. Chronic ?-alanine supplementation can increase muscle carnosine content when taken for several weeks, and studies have shown that supplementation between 4 and 24 weeks can improve high-intensity exercise capacity, with the gains in exercise associated with the increase in muscle carnosine content. Although several studies have demonstrated the efficacy of ?-alanine supplementation as an ergogenic aid, there are a number of confounding factors that may modify its effect, including exercise type, duration and mode, training status and cosupplementation, which may influence the effects of ?-alanine supplementation. The aim of our systematic review and meta-analysis was to determine the effects of ?-alanine supplementation accounting for these potential modifying factors.

Citation

SAUNDERS, B., VIRGILE, A., ELLIOTT-SALE, K. J., ARTIOLI, G.G., SWINTON, P.A., DOLAN, E., ROSCHEL, H., SALE, C. and GUALANO, B. 2020. Infographic. A systematic review and meta-analysis of the effect of ?-alanine supplementation on exercise capacity and performance. British journal of sports medicine [online], 54(15), pages 925-926. Available from: http://dx.doi.org/10.1136/bjsports-2019-101129

• Journal Article Type: Article
• Acceptance Date: Jul 18, 2019
• Online Publication Date: Aug 2, 2019
• Publication Date: Aug 31, 2020
• Deposit Date: Sep 6, 2019
• Publicly Available Date: Sep 6, 2019
• Journal: British Journal of Sports Medicine
• Print ISSN: 0306-3674
• Electronic ISSN: 1473-0480
• Publisher: BMJ Publishing Group
• Peer Reviewed: Peer Reviewed
• Volume: 54
• Issue: 15
• Pages: 925-926
• DOI: https://doi.org/10.1136/bjsports-2019-101129
• Keywords: Elite performance; Exercise; Nutrition; Supplements
• Public URL: https://rgu-repository.worktribe.com/output/356412