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Infographic: a systematic review and meta-analysis of the effect of β-alanine supplementation on exercise capacity and performance.

Saunders, Bryan; Virgile, Adam; Elliott-Sale, Kirsty Jayne; Artioli, Guilherme Giannini; Swinton, Paul A; Dolan, Eimear; Roschel, Hamilton; Sale, Craig; Gualano, Bruno

Authors

Bryan Saunders

Adam Virgile

Kirsty Jayne Elliott-Sale

Guilherme Giannini Artioli

Paul A Swinton

Eimear Dolan

Hamilton Roschel

Craig Sale

Bruno Gualano



Abstract

Carnosine (β-alanyl-L-histidine) is an abundant compound in skeletal muscle, suggesting it plays an important role during exercise, with a key physiological role considered to be intracellular pH regulation. Chronic β-alanine supplementation can increase muscle carnosine content when taken for several weeks, and studies have shown that supplementation between 4 and 24 weeks can improve high-intensity exercise capacity, with the gains in exercise associated with the increase in muscle carnosine content. Although several studies have demonstrated the efficacy of β-alanine supplementation as an ergogenic aid, there are a number of confounding factors that may modify its effect, including exercise type, duration and mode, training status and cosupplementation, which may influence the effects of β-alanine supplementation. The aim of our systematic review and meta-analysis was to determine the effects of β-alanine supplementation accounting for these potential modifying factors.

Journal Article Type Article
Journal British Journal of Sports Medicine
Print ISSN 0306-3674
Electronic ISSN 1473-0480
Publisher BMJ Publishing Group
Peer Reviewed Peer Reviewed
Institution Citation SAUNDERS, B., VIRGILE, A., ELLIOTT-SALE, K. J., ARTIOLI, G.G., SWINTON, P.A., DOLAN, E., ROSCHEL, H., SALE, C. and GUALANO, B. 2019. Infographic: a systematic review and meta-analysis of the effect of β-alanine supplementation on exercise capacity and performance. British journal of sports medicine [online], Online First. Available from: http://dx.doi.org/10.1136/bjsports-2019-101129
DOI https://doi.org/10.1136/bjsports-2019-101129
Keywords Elite performance; Exercise; Nutrition; Supplements

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