A novel method to quantify fibrin-fibrin and fibrin-α2AP cross-links in thrombi formed from human trauma patient plasma.

Morrow, Gael B.; Flannery, Sarah; Charles, Philip D.; Heilig, Raphael; Feller, Timea; McQuilten, Zoe; Wake, Elizabeth; Ariens, Robert A.S.; Winearls, James; Mutch, Nicola J.; Fischer, Roman; Laffan, Mike A.; Curry, Nicola

doi:10.1016/j.jtha.2024.03.001

All Outputs (2)

Are all fibrinogen concentrates the same? The effects of two fibrinogen therapies in an afibrinogenemic patient and in a fibrinogen deficient plasma model: a clinical and laboratory case report. (2024)
Journal Article
GOODARZI, S., ABU-HANNA, J., HARPER, S., KHAN, D., MORROW, G. and CURRY, N. 2024. Are all fibrinogen concentrates the same? The effects of two fibrinogen therapies in an afibrinogenemic patient and in a fibrinogen deficient plasma model: a clinical and laboratory case report. Frontiers in medicine [online], 11, article 1391422. Available from: https://doi.org/10.3389/fmed.2024.1391422

The choice of treatments for inherited, or acquired, fibrinogen deficient states is expanding and there are now several fibrinogen concentrate therapies commercially available. Patients with the rare inherited bleeding disorder, afibrinogenemia, comm... Read More about Are all fibrinogen concentrates the same? The effects of two fibrinogen therapies in an afibrinogenemic patient and in a fibrinogen deficient plasma model: a clinical and laboratory case report..

A novel method to quantify fibrin-fibrin and fibrin-α2AP cross-links in thrombi formed from human trauma patient plasma. (2024)
Journal Article
MORROW, G.B., FLANNERY, S., CHARLES, P.D., HEILIG, R., FELLER, T., MCQUILTEN, Z., WAKE, E., ARIENS, R.A.S., WINEARLS, J., MUTCH, N.J., FISCHER, R., LAFFAN, M.A. and CURRY, N. [2024]. A novel method to quantify fibrin-fibrin and fibrin-α2AP cross-links in thrombi formed from human trauma patient plasma. Journal of thrombosis and haemostasis [online], Articles in Press. Available from: https://doi.org/10.1016/j.jtha.2024.03.001

The widespread use of the anti-fibrinolytic agent, tranexamic acid (TXA), interferes with the quantification of fibrinolysis by dynamic laboratory assays such as clot lysis, making it difficult to measure fibrinolysis in many trauma patients. At the... Read More about A novel method to quantify fibrin-fibrin and fibrin-α2AP cross-links in thrombi formed from human trauma patient plasma..