All Outputs (2)

A serpin with a finger in many PAIs: PAI-1’s central function in thromboinflammation and cardiovascular disease. (2021)
Journal Article
MORROW, G.B., WHYTE, C.S. and MUTCH, N.J. 2021. A serpin with a finger in many PAIs: PAI-1’s central function in thromboinflammation and cardiovascular disease. Frontiers in cardiovascular medicine [online], 8, article 653655. Available from: https://doi.org/10.3389/fcvm.2021.653655

Plasminogen activator inhibitor 1 (PAI-1) is a member of the serine protease inhibitor (serpin) superfamily. PAI-1 is the principal inhibitor of the plasminogen activators, tissue plasminogen activator (tPA), and urokinase-type plasminogen activator... Read More about A serpin with a finger in many PAIs: PAI-1’s central function in thromboinflammation and cardiovascular disease..

Fibrinogen replacement therapy for traumatic coagulopathy: does the fibrinogen source matter? (2021)
Journal Article
MORROW, G.B., CARLIER, M.S.A., DASGUPTA, S., CRAIGEN, F.B., MUTCH, M.J. and CURRY, N. 2021. Fibrinogen replacement therapy for traumatic coagulopathy: does the fibrinogen source matter? International journal of molecular sciences [online], 22(4), article 2185. Available from: https://doi.org/10.3390/ijms22042185

Fibrinogen is the first coagulation protein to reach critically low levels during traumatic haemorrhage. There have been no differential effects on clinical outcomes between the two main sources of fibrinogen replacement: cryoprecipitate and fibrinog... Read More about Fibrinogen replacement therapy for traumatic coagulopathy: does the fibrinogen source matter?.