All Outputs (2)

Overcoming CD spectroscopy sample preparation challenges in protein structural analysis for biosimilars. (2024)
Working Paper
AGBELUSI, T., PANCHOLI, K., KUMAR, H.S. and KUMAR, A. 2024. Overcoming CD spectroscopy sample preparation challenges in protein structural analysis for biosimilars. Preprints [online]. Available from: https://doi.org/10.20944/preprints202401.0441.v1

Circular dichroism (CD) spectroscopy is a valuable tool in the pharmaceutical industry for determining the secondary and tertiary structure, folding, stability, and interactions of proteins in biosimilars. However, protein aggregation due to its inte... Read More about Overcoming CD spectroscopy sample preparation challenges in protein structural analysis for biosimilars..

Manganese catalysed synthesis of polyketones using hydrogen borrowing approach. (2024)
Working Paper
KULYABIN, P., MAGDYSYUK, O., NADEN, A.B., DAWSON, D.M., PANCHOLI, K., WALKER, M., VASSALLI, M. and KUMAR, A. 2024. Manganese catalysed synthesis of polyketones using hydrogen borrowing approach. ChemRxiv [online]. Available from: https://doi.org/10.26434/chemrxiv-2023-8lv3v-v2

We report here a new method to make polyketones from the coupling of diketones and diols using a manganese pincer complex. The methodology allows us to access a new type of polyketone (polyarylalkylketone) containing aryl, alkyl, and ether functional... Read More about Manganese catalysed synthesis of polyketones using hydrogen borrowing approach..