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Impact of the MTHFR C677T polymorphism on one-carbon metabolites: evidence from a randomised trial of riboflavin supplementation. (2020)
Journal Article
ROONEY, M., BOTTIGLIERI, T., WASEK-PATTERSON, B., MCMAHON, A., HUGHES, C.F., MCCANN, A., HORIGAN, G., STRAIN, J.J., MCNULTY, H. and WARD, M. 2020. Impact of the MTHFR C677T polymorphism on one-carbon metabolites: evidence from a randomised trial of riboflavin supplementation. Biochimie [online], 173, pages 91-99. Available from: https://doi.org/10.1016/j.biochi.2020.04.004

Homozygosity for the C677T polymorphism in MTHFR (TT genotype) is associated with a 24–87% increased risk of hypertension. Blood pressure (BP) lowering was previously reported in adults with the TT genotype, in response to supplementation with the MT... Read More about Impact of the MTHFR C677T polymorphism on one-carbon metabolites: evidence from a randomised trial of riboflavin supplementation..