All Outputs (3)

Folate, genomic stability and colon cancer: the use of single cell gel electrophoresis in assessing the impact of folate in vitro, in vivo and in human biomonitoring. (2018)
Journal Article
CATALA, G.N., BESTWICK, C.S., RUSSELL, W.R., TORTORA, K., GIOVANNELLI, L., MOYER, M.P., LENDOIRO, E. and DUTHIE, S.J. 2019. Folate, genomic stability and colon cancer: the use of single cell gel electrophoresis in assessing the impact of folate in vitro, in vivo and in human biomonitoring. Mutation research: genetic toxicology and environmental mutagenesis [online], 843, pages 73-80. Available from: https://doi.org/10.1016/j.mrgentox.2018.08.012

Intake of folate (vitamin B9) is strongly inversely linked with human cancer risk, particularly colon cancer. In general, people with the highest dietary intake of folate or with high blood folate levels are at a reduced risk (approx. 25%) of develop... Read More about Folate, genomic stability and colon cancer: the use of single cell gel electrophoresis in assessing the impact of folate in vitro, in vivo and in human biomonitoring..

Oral human papillomavirus infection in England and associated risk factors: a case control study. (2018)
Journal Article
HEARNDEN, V., MURDOCH, C., D'APICE, K., DUTHIE, S., HAYWARD, N.J. and POWERS, H.J. 2018. Oral human papillomavirus infection in England and associated risk factors: a case control study. BMJ open [online], 8(8), article number 022497. Available from: https://doi.org/10.1136/bmjopen-2018-022497

Objectives - This study was conducted to determine the prevalence of and associated risk factors for infection with oral high-risk human papillomavirus (HR-HPV) in adult participants within England, and to explore any association with oral mucosal bu... Read More about Oral human papillomavirus infection in England and associated risk factors: a case control study..

Caspase-independence and characterization of bisnaphthalimidopropyl spermidine induced cytotoxicity in HL60 cells. (2018)
Journal Article
BESTWICK, C., MILNE, L., DANCE, A.-M., COCHENNEC, G., CRUICKSHANK, G., ALLAIN, E., CONSTABLE, L., DUTHIE, S.J. and KONG THOO LIN, P. 2018. Caspase-independence and characterization of bisnaphthalimidopropyl spermidine induced cytotoxicity in HL60 cells. Toxicology in vitro [online], 52, pages 342-350. Available from: https://doi.org/10.1016/j.tiv.2018.06.023

Bisnaphthalimides are DNA intercalators of potential use as chemotherapeutics but for which the range of mechanism of action is only gradually being elucidated. Using human promyelocytic HL-60 cells, we extend characterization of the cytotoxicity of... Read More about Caspase-independence and characterization of bisnaphthalimidopropyl spermidine induced cytotoxicity in HL60 cells..