All Outputs (2)

A serpin with a finger in many PAIs: PAI-1’s central function in thromboinflammation and cardiovascular disease. (2021)
Journal Article
MORROW, G.B., WHYTE, C.S. and MUTCH, N.J. 2021. A serpin with a finger in many PAIs: PAI-1’s central function in thromboinflammation and cardiovascular disease. Frontiers in cardiovascular medicine [online], 8, article 653655. Available from: https://doi.org/10.3389/fcvm.2021.653655

Plasminogen activator inhibitor 1 (PAI-1) is a member of the serine protease inhibitor (serpin) superfamily. PAI-1 is the principal inhibitor of the plasminogen activators, tissue plasminogen activator (tPA), and urokinase-type plasminogen activator... Read More about A serpin with a finger in many PAIs: PAI-1’s central function in thromboinflammation and cardiovascular disease..

Fibrinolytic abnormalities in acute respiratory distress syndrome (ARDS) and versatility of thrombolytic drugs to treat COVID-19. (2020)
Journal Article
WHYTE, C.S., MORROW, G.B., MITCHELL, J.L., CHOWDARY, P. and MUTCH, N.J. 2020. Fibrinolytic abnormalities in acute respiratory distress syndrome (ARDS) and versatility of thrombolytic drugs to treat COVID-19. Journal of thrombosis and haemostasis [online], 18(7), pages 1548-1555. Available from: https://doi.org/10.1111/jth.14872

The global pandemic of coronavirus disease 2019 (COVID‐19) is associated with the development of acute respiratory distress syndrome (ARDS), which requires ventilation in critically ill patients. The pathophysiology of ARDS results from acute inflamm... Read More about Fibrinolytic abnormalities in acute respiratory distress syndrome (ARDS) and versatility of thrombolytic drugs to treat COVID-19..