Measuring DNA modifications with the comet assay: a compendium of protocols.
(2023)
Journal Article
COLLINS, A., MØLLER, P., GAJSKI, G., DUTHIE, S.J. et al. 2023. Measuring DNA modifications with the comet assay: a compendium of protocols. Nature protocols [online], 18, pages 929-989. Available from: https://doi.org/10.1038/s41596-022-00754-y
The comet assay is a versatile method to detect nuclear DNA damage in individual eukaryotic cells, from yeast to human. The types of damage detected encompass DNA strand breaks and alkali-labile sites (e.g., apurinic/apyrimidinic sites), alkylated an... Read More about Measuring DNA modifications with the comet assay: a compendium of protocols..