Pathological response post neoadjuvant therapy for locally advanced rectal cancer is an independent predictor of survival. [Dataset]

Abstract

Neoadjuvant treatment (NaT) for locally advanced rectal cancer prior to surgery has led to improved outcomes. However, the relationship between pathological response to NaT and survival is not entirely clear. The aim of this study was to assess the degree of pathological response to NaT on survival outcomes. The accompanying file contains supplementary material.

Citation

ON, J., SHIM, J., MACKAY, C., MURRAY, G., SAMUEL, L., PARNABY, C. and RAMSAY, G. 2021. Pathological response post neoadjuvant therapy for locally advanced rectal cancer is an independent predictor of survival. [Dataset]. Colorectal disease [online], 23(6), pages 1326-1333. Available from: https://onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1111%2Fcodi.15512&file=codi15512-sup-0001-Supinfo.docx

• Acceptance Date: Dec 22, 2020
• Online Publication Date: Jan 4, 2021
• Publication Date: Jun 30, 2021
• Deposit Date: Oct 19, 2021
• Publicly Available Date: Jan 5, 2022
• Publisher: Wiley-VCH Verlag
• DOI: https://doi.org/10.1111/codi.15512
• Keywords: Rectal cancer; Tumour regression grade; Pathological response
• Public URL: https://rgu-repository.worktribe.com/output/1499943
• Related Public URLs: https://rgu-repository.worktribe.com/output/1447175
• Type of Data: Supplementary figure and tables.
• Collection Date: Dec 31, 2017
• Collection Method: Clinical and pathological data were collected from a prospectively maintained pathology database between 2005 and 2017. The primary outcome was the overall survival based on pathological response categorized as complete, good partial, partial and minimal. Univariate and multivariate analyses were conducted to identify variables predictive of survival. Cox proportional hazard ratios were used for survival. A full description of methods can be found in the published full text article (https://doi.org/10.1111/codi.15512).