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Pathological response post neoadjuvant therapy for locally advanced rectal cancer is an independent predictor of survival. [Dataset]

Contributors

Jason On
Data Collector

Craig Mackay
Data Collector

Graeme Murray
Data Collector

Leslie Samuel
Data Collector

Craig Parnaby
Data Collector

George Ramsay
Data Collector

Abstract

Neoadjuvant treatment (NaT) for locally advanced rectal cancer prior to surgery has led to improved outcomes. However, the relationship between pathological response to NaT and survival is not entirely clear. The aim of this study was to assess the degree of pathological response to NaT on survival outcomes. The accompanying file contains supplementary material.

Citation

ON, J., SHIM, J., MACKAY, C., MURRAY, G., SAMUEL, L., PARNABY, C. and RAMSAY, G. 2021. Pathological response post neoadjuvant therapy for locally advanced rectal cancer is an independent predictor of survival. [Dataset]. Colorectal disease [online], 23(6), pages 1326-1333. Available from: https://onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1111%2Fcodi.15512&file=codi15512-sup-0001-Supinfo.docx

Acceptance Date Dec 22, 2020
Online Publication Date Jan 4, 2021
Publication Date Jun 30, 2021
Deposit Date Oct 19, 2021
Publicly Available Date Jan 5, 2022
Publisher Wiley-VCH Verlag
DOI https://doi.org/10.1111/codi.15512
Keywords Rectal cancer; Tumour regression grade; Pathological response
Public URL https://rgu-repository.worktribe.com/output/1499943
Related Public URLs https://rgu-repository.worktribe.com/output/1447175
Type of Data Supplementary figure and tables.
Collection Date Dec 31, 2017
Collection Method Clinical and pathological data were collected from a prospectively maintained pathology database between 2005 and 2017. The primary outcome was the overall survival based on pathological response categorized as complete, good partial, partial and minimal. Univariate and multivariate analyses were conducted to identify variables predictive of survival. Cox proportional hazard ratios were used for survival. A full description of methods can be found in the published full text article (https://doi.org/10.1111/codi.15512).

Files

ON 2021 Pathological response (SUPPLEMENTARY MATERIAL) (201 Kb)
PDF

Copyright Statement
This is the peer reviewed version of the following article: ON, J., SHIM, J., MACKAY, C., MURRAY, G., SAMUEL, L., PARNABY, C. and RAMSAY, G. 2021. Pathological response post neoadjuvant therapy for locally advanced rectal cancer is an independent predictor of survival. [Dataset]. Colorectal disease [online], 23(6), pages 1326-1333, which has been published in final form at https://onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1111%2Fcodi.15512&file=codi15512-sup-0001-Supinfo.docx. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.





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