Bioactivity of two Turkish endemic centaurea species, and their major constituents.

Shoeb, Mohammad; MacManus, Stephen M.; Jaspars, Marcel; Kong-Thoo-Lin, Paul; Nahar, Lutfun; Celik, Sezgin; Sarker, Satyajit D.

Abstract

The antioxidant activity, general toxicity and cytotoxicity of the methanol extracts of Centaurea urvillei subs, armata and C. mucronifera have been assessed, respectively, by the DPPH assay, the brine shrimp lethality and the MTT cytotoxicity assays. The reversed-phase HPLC analysis of the methanol extracts afforded two bioactive dibenzylbutyrolactone-type lignans, matairesinoside (1) and arctiin (2). The structures of these lignans were elucidated by comprehensive spectroscopic analyses as well as by the direct comparison of experimental data with respective literature data.

Citation

SHOEB, M., MACMANUS, S.M., JASPARS, M., KONG THOO LIN, P., NAHAR, L., CELIK, S. and SARKER, S.D. 2007. Bioactivity of two Turkish endemic centaurea species, and their major constituents. Revista Brasileira de Farmacognosia/Brazilian journal of pharmacognosy [online], 17(2), pages 155-159. Available from: https://doi.org/10.1590/S0102-695X2007000200003

• Journal Article Type: Article
• Acceptance Date: Apr 20, 2007
• Online Publication Date: Jul 20, 2007
• Publication Date: Jun 30, 2007
• Deposit Date: Aug 22, 2022
• Publicly Available Date: Aug 22, 2022
• Journal: Revista Brasileira de Farmacognosia
• Print ISSN: 0102-695X
• Publisher: Sociedade Brasileira de Farmacognosia
• Peer Reviewed: Peer Reviewed
• Volume: 17
• Issue: 2
• Pages: 155-159
• DOI: https://doi.org/10.1590/S0102-695X2007000200003
• Keywords: Centaurea urvillei subs. armata; Centaurea mucronifera; Asteraceae; Compositae; Lignan; Arctiin; Matairesinoside; DPPH; MTT; Brine shrimp lethality assay
• Public URL: https://rgu-repository.worktribe.com/output/1740206